Qua Re qui possum non esse popularis: The representation of Populares in the Late Roman Republic.

The terms popularis and optimate have been employed in both ancient and modern literature to interpret late Roman Republican politics. The purpose of this work is to express the diversity and change of the popularis label from 133 to 88 B.C. as a consequence of developing political practices. A chronological assessment of five key popularis tribunes in this period; Ti. Sempronius Gracchus, G. Sempronius Gracchus, L. Appuleius Saturninus, M. Livius Drusus and P. Sulpicius Rufus determines the variation in political methodologies exploited by these men in response to an optimate opposition. An assessment of Cicero’s works then considers how the discrepancies exhibited by these politicians could be manipulated for oratorical advantage. This subsequently reveals the perception of pre-Sullan populares in the time of Cicero, a generation later. This work ultimately aims to demonstrate the individualistic nature of late Republican politicians, the evolution of political practice in the period and the diverse employment of political labels in contemporary sources

Improved pH buffering agent for sodium hypochlorite

Sodium citrate/citric acid was found to be an effective buffer for pH control when used with sodium hypochlorite. The mixture does not corrode aluminum. The buffer appears to form a type of conversion coating that may provide corrosion-resistant properties to aluminum in other applications

Segmentation of the Travel Market in London: Estimates of Elasticities and Values of Travel Time.

This paper reports background research carried out for an ESRC funded research project entitled "Assessing the Benefits and Incidence of Road Pricing in London". The first two stages of this work are reported here. The first stage was to segment the market for car use in Central and Inner London according to the salient characteristics of users. The second stage was to make estimates of the range of probable values of time and elasticities for each segment of the market using secondary data. A thorough literature search was undertaken and we have liaised with other relevant work in progress. The results of our distillation of what we have found/borrowed are given in section 3. Own price elasticities of demand are presented disaggregated by mode and journey purpose. In the case of car, latest evidence emerging from the DoT study of road pricing in London has been included, showing how elasticities might be expected to rise as the toll is increased radically such as to have severe `income effects'. Values of Time are presented disaggregated by mode, journey purpose and household income group. There is a difficulty, however, in using these values in mode choice transport models and this is discussed in Section 4. Section 5 presents conclusions and discusses application of the results of this paper in the ESRC project. Section 6 lists references and Section 7 is an Appendix containing brief highlights from many of the source articles consulted in our literature review

Priming in interpersonal contexts: Implications for affect and behavior

Priming stereotypes can lead to a variety of behavioral outcomes, including assimilation, contrast, and response behaviors. However, the conditions that give rise to each of these outcomes are unspecified. Furthermore, theoretical accounts posit that prime-to-behavior effects are either direct (i.e., unmediated) or mediated by cognitive processes, whereas the role of affective processes has been largely unexplored. The present research directly investigated both of these issues. Three experiments demonstrated that priming a threatening social group ("hoodies") influences both affect and behavior in an interpersonal context. Hoodie priming produced both behavioral avoidance and several affective changes (including social apprehension, threat sensitivity, and self-reported anxiety and hostility). Importantly, avoidance following hoodie priming was mediated by anxiety and occurred only under conditions of other-(but not self-) focus. These results highlight multiple routes through which primes influence affect and behavior, and suggest that attention to self or others determine the nature of priming effects

Gait Extraction and Description by Evidence-Gathering

Using gait as a biometric is of increasing interest, yet there are few model-based, parametric, approaches to extract and describe moving articulated objects. One new approach can detect moving parametric objects by evidence gathering, hence accruing known performance advantages in terms of performance and occlusion. Here we show how that the new technique can be extended not only to extract a moving person, but also to extract and concurrently provide a gait signature for use as a biometric. We show the natural relationship between the bases of these approaches, and the results they can provide. As such, these techniques allow for gait extraction and description for recognition purposes, and with known performance advantages of a well-established vision technique

Anchoring effects in the development of false childhood memories

When people receive descriptions or doctored photos of events that never happened, they often come to remember those events. But if people receive both a description and a doctored photo, does the order in which they receive the information matter? We asked people to consider a description and a doctored photograph of a childhood hot air balloon ride, and we varied which medium they saw first. People who saw a description first reported more false images and memories than people who saw a photo first, a result that fits with an anchoring account of false childhood memories

Hydrographic Study of Peirce Island Wastewater Treatment Plant Effluent in the Piscataqua River of Portsmouth, New Hampshire: Report of Findings from the December 10 – 14, 2012 Study Period

In order to assist the New Hampshire Department of Environmental Services (NHDES) evaluate the impact of treated wastewater effluent from Peirce Island Wastewater Treatment Plant (WWTP) to the Lower Piscataqua River and Portsmouth Harbor a hydrographic dye study was conducted in December 2012 in Portsmouth, NH. Eight (8) shellfish cages with American oysters (Crassostrea virginica) and blue mussels (Mytilus edulis) were deployed both upstream and downstream of the Peirce Island WWTP in the Piscataqua River, Little Harbor, and the entrance of Little Bay. Eight (8) mini CTDs that monitor conductivity/salinity, temperature, and depth, and six (6) moored fluorometers, which measure dye tagged effluent from the Peirce Island WWTP were attached to the subsurface cages. A fifty (50) gallon mixture of Rhodamine WT dye and distilled water was injected into WWTP on December 11, 2012 for a half tidal cycle (approximately 12.4 hours). Additionally, boat tracking fluorometers connected with a mobile geographic information system (GIS) were used to measure dye levels on the surface in situ and in real time. Microbiological analyses of fecal coliform (FC), male-specific coliphage (MSC), Norovirus (NoV) genogroup I (GI) and genogroup II (GII), and Adenovirus (AdV) were conducted on WWTP influent and effluent composite samples collected with automated samplers to determine the WWTP efficiency in reducing indicator bacteria and viruses. Microbiological sampling and testing of oysters and mussels from the eight (8) sentinel cages was conducted to assess the impact of WWTP effluent on shellfish growing areas and growing area classifications. Prior to conducting the study, the assumption was that the FDA’s recommended minimum dilution of 1000:1was not applicable in this situation because the recommended dilution is based on a WWTP having at least secondary treatment. The microbiological findings in shellfish samples, wastewater samples from the Peirce Island WWTP, and the results of the dye study, confirm that a minimum of 1,000:1 dilution with respect to Peirce Island WWTP is currently not applicable for this WWTP. The FDA and NHDES recommend continued MSC testing of wastewater samples from the WWTP before and after the WWTP upgrade. The FDA and NHDES recommend a future field study after the WWTP upgrade in order to delineate the 1,000:1 dilution zone

Poverty and some of its effects upon school children

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Loss of SKI Expression in Testicular Cancer Leads to an Enhanced Invasive Phenotype Through Both BMP-Dependent and BMP-Independent Pathways

The proto-oncogene SKI is a transcription factor and a co-repressor of the TGFβ superfamily, including TGF β and BMP. However, additional data suggests that SKI may function as a tumor suppressor in some cell types. The TGFβ superfamily has been implicated in cancer progression and germ cell migration. Testicular cancer afflicts men during their peak reproductive years and is the most common cancer among men of this age group. Cisplatin-based chemotherapy is the standard treatment for testicular cancer. This treatment can lead to undesirable side effects, including infertility. We have shown that SKI expression is decreased in testicular germ cell tumors compared to normal testis. The hypothesis of this work is that decreased SKI expression promotes testicular cancer progression by allowing unregulated TGFβ superfamily signaling, conferring an increased ability of testicular cancer cells to invade and metastasize. To test the effects of decreased SKI in testicular cancer, we used a human embryonal carcinoma cell line, NCCIT. We found that transient SKI-knockdown confers an increased ability to migrate and invade, but does not affect proliferation, in NCCIT cells. Forced overexpression of SKI in NCCIT cells resulted in decreased migration and invasion compared to control cells. We next investigated whether TGFβ or BMP enhanced the invasive phenotype of stable SKI-knockdown NCCIT cells. NCCIT cells stably transfected with nonspecific shRNA were used as a control. Addition of TGFβ or TGFβ blocking antibody had no effect on the migration of either SKI-knockdown cells or control cells. Addition of BMP4 enhanced migration in SKI-deficient NCCIT cells but had no effect on control cells. Treatment with noggin, a BMP inhibitor, reduced the migration of SKI-deficient NCCIT cells back to the level of control cells. These data imply that in NCCIT cells with decreased SKI expression, the BMP pathway, but not the TGFβ pathway, promotes migration. Microarray analysis was performed to identify downstream targets of SKI that may be involved in cellular invasion. CXCR4 expression was increased in SKI- knockdown cells compared to control cells, but CXCR4 expression was not affected by treatment with BMP. Signaling partners CXCR4 and SDF1 have been implicated in germ cell migration and cancer metastasis. Addition of SDF1 enhanced the invasive potential of SKI-deficient cells but had no effect on control cells. Addition of AMD3100, a potent and specific inhibitor of CXCR4, blocked the effects seen with SDF1. These data, taken together with the BMP data, imply that decreased SKI expression in NCCIT cells leads to enhanced invasion through both BMP-dependent and BMP-independent mechanisms. This research provides insight into the mechanism behind testicular cancer metastasis, and it identifies the BMP signaling pathway and CXCR4/SDF1 as potential targets for the development of new therapies to treat patients with metastatic testicular cancer