Ent-kaurene and ent-beyerene diterpenoids and other constituents of Thecacoris batesii

Two novel diterpenoids, thecacorins A (1) and B (2), were isolated from Thecacoris batesii and their structures were established as ent-3b,20-epoxy-16-kaurene-3a,12b-diol and ent-15-beyerene-2b,3b-diol, respectively, on the basis of extensive spectroscopic analysis, especially, 1D NMR spectra, in conjunction with 2D experiments, COSY, NOESY, HMQC and HMBC. KEY WORDS: Diterpenoids, Thecacorin A, Thecacorin B, Ent-3b,20-epoxy-16-kaurene-3a,12b-diol, Ent-15-beyerene-2b,3b-diol, Thecacoris batesii  Bull. Chem. Soc. Ethiop. 2007, 21(1), 89-94

(2E,4R,5R,6S)-2-(4,5,6-Trihydroxycyclohex-2-en-1-ylidene)acetonitrile

The crystal structure of the title compound, C8H9NO3, is characterized by a complex three-dimensional hydrogen-bond network in which every molecule is connected to six symmetry-related neighbours

<b><i>Ent</i>-kaurene and <i>ent</i>-beyerene diterpenoids and other constituents of <i>Thecacoris batesii</i></b>

Two novel diterpenoids, thecacorins A (1) and B (2), were isolated from Thecacoris batesii and their structures were established as ent-3&beta;,20-epoxy-16-kaurene-3&alpha;&alpha;,12&beta;-diol and ent-15-beyerene-2&beta;,3&beta;-diol, respectively, on the basis of extensive spectroscopic analysis, especially, 1D NMR spectra, in conjunction with 2D experiments, COSY, NOESY, HMQC and HMBC