Core electron densities of coronal polar plumes

The electron density in the cores of coronal polar plumes that is determined from observations will depend upon the assumed electron density distribution through the plume in a direction normal to its axis. Core electron densities obtained by Saito (1965) and by Newkirk and Harvey (1968) were derived using different assumed electron density profiles, and are not in agreement. We have re-discussed Saito's data using Newkirk and Harvey's electron density profile and find that the disagreement persists. Whether this indicates a true variation in electron density in plume cores cannot now be stated. Errors in the electron densities derived here may arise through errors in measuring the angles θ and α which enter into the analysis. While plausible variations in θ produce no appreciable errors in core electron density, plausible variations in α may introduce appreciable errors into the determinations of that quantity.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43726/1/11207_2004_Article_BF00153112.pd

V. Yu.Chagovets – first membranologist of Ukraine: vital and creative way

Vasyl Chagovets was first to apply the theory of electrolytic dissociation in electrophysiology, formulated the ionic theory of origin of bioelectric potentials and condenser theory of electric irritation of living tissues. He proposed using electrogastrogram as a research method of secretory function of stomach. He first by grounded expedience of application of mathematical methods in biology

The impact of water-soluble C60 fullerenes on the development of acute colitis in rats

Anti-inflammatory drugs are traditionally applied for the treatment of acute colitis of various etiologies. However, they have several disadvantages due to intestinal and extraintestinal complications and lowefficiency. Therefore, a search for new agents which would be effective at colonic inflammation is relevant. Potential anti-inflammatory and protective properties of the water-soluble C60 fullerenes on rat acute ulcerative colitis model were assessed. Acute colitis was induced by rectal administration of 0.5 ml of 10% acetic acid solution. C60 fullerenes (0.5 mg/kg body weight) in the stable aqueous solution were administered intraperitoneally or rectally at 24 and 48 h after the colitis induction. Animals were euthanized at 24 h after the last administration. State of the colon was evaluated macroscopically by 10-grade scale, and the colon epithelial barrier permeability was assessed for diurnal phenol red excretion. The levels of serum blood transaminases, creatinine and urea were also measured for liver and kidney state assessment. Colonic lesions were reduced in some animals (3 of total number of 6) by C60 fullerenes administered intraperitoneally. Moreover, mucosal dama­ge was significantly weaker in all animals under C60 fullerenes rectal administration (3 grades vs 5). C60 fullerenes applied by both methods partially corrected local and systemic changes: colon mucosa epithelial barrier and kidney and liver functions were restored. Thus, C60 fullerenes correct local and systemic consequences of the acute colitis. The protective effects of C60 fullerenes are more pronounced at topical administration compared with the intraperitoneal one

INFLUENCE OF C60-FULLERENE AQUEOUS COLLOID SOLUTION ON LIVER AND PANCREAS MORPHOLOGICAL STATE AND BLOOD AMINOTRANSFERASES OF RATS WITH EXPERIENCED ACUTE CHOLANGITIS

Aim of the work was to investigate the suspended C60-fulleren effect on liver and pancreas state under intraperitoneal and intragastrial administration on rat experimental cholangitis model. Acute cholangitis was simulated by a single ingestion of ɑ-naphthyl isothiocyanate — ANIT. C60-fullerene aqueous colloid solution (C60FAS, 0.15 mg/ml) was administered to animals at a volume containing C60-fullerenes at a dose of 0.5 mg/kg body weight in 24 and 48 h after ANIT administration. After72 h of the experiment, the animals were euthanized. Blood serum ALT and AST activities were measured, the liver and pancreas states were analyzed by light-microscopy level. It was found that intragastrial and intraperitoneal administration of C60FAS contributes to the correction of negative effects in the liver and pancreas caused by the induction of acute cholangitis. This was proved by the normalization of ALT activity, reduction of pancreatic parenchymal edema and liver fibrosis, and increased blood flow in these organs. Application of C60FAS could improve the state of the liver and pancreas under acute cholangitis in rats