1,336 research outputs found

    ТЕОРЕТИЧНІ АСПЕКТИ ОЦІНЮВАННЯ РЕЗУЛЬТАТИВНОСТІ УПРАВЛІННЯ КАПІТАЛОМ ПІДПРИЄМСТВА

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    The determining vector of the transformation of the company capital management system is the search and integration of the latest business management tools that are oriented at achieving the planned results, and have the potential for increased efficiency and effectiveness of management actions in relation to capital and the enterprise’s activity as a whole. In view of this, the research and improvement of the conceptual provisions for performance assessment of company capital management becomes relevant. The purpose of the article is to improve the theoretical basis of performance assessment of company capital management from the point of essence’s clarification of the main concepts, principles and technology of the process. On the basis of generalization and critical analysis of theoretical knowledge of company capital management and the effectiveness of this process, there is an author definition of following concepts of “company capital”, “company capital management system”, “process of company capital management”, “the effectiveness of company capital management” in the article. There are revealed the principles, the observance of which ensure the adequacy of the object, criteria, procedures and tools for performance assessment of the company capital management in certain requirements of the subjects of assessment. It is proposed the referent model of performance assessment of company the capital management for practical use and it was determined the prospects of further scientific researches.На основании обобщения и критического анализа вопросов теории управления капиталом предпринимательских структур и результативности этого процесса обоснованы концептуальные положения оценки результативности управления капиталом предприятия. Изложена авторская точка зрения относительно трактовки капитала предприятия, системы и процесса управления им, сути и содержания понятия «результативность управления капиталом предприятия», моделирования процесса оценки результативности управленческих действий. Определены принципы, соблюдение которых обеспечивает повышение объективности результатов оценки управления капиталом и их практическую значимость для своевременной корректировки управленческих действий.На підставі узагальнення і критичного аналізу теоретичних знань з управління капіталом підприємницьких структур і результативності цього процесу обґрунтовано концептуальні положення оцінювання результативності управління капіталом підприємства. Наведена авторська точка зору щодо трактування капіталу підприємства, системи і процесу управління ним, суті та змістовності поняття «результативність управління капіталом підприємства», моделювання процесу оцінювання результативності управлінських дій. Визначено принципи, що забезпечують підвищення об’єктивності результатів оцінювання та їхню практичну значущість для своєчасного коригування управлінських дій щодо капіталу підприємства

    К ВОПРОСУ О ЩАДИМОСТИ В ХИРУРГИИ ОТОСКЛЕРОЗА

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    The article deals with optimization of the current technical methods in operations on the osteosclerotic stapes aimed at minimization of any trauma in the inner ear and at maximal possible safety for the sound-conducting structures - the factors that guarantee the functional results of the surgery.Статья посвящена оптимизации технических приемов современных способов операций на стремени при отосклерозе с целью как минимизации травматичности внутреннего уха, так и максимально возможной сохранности звукопроводящих структур среднего уха, что во многом и определят функциональный результат операции

    ВОЗМОЖНОСТИ ЭЛЕКТРОМАГНИТНОЙ НАВИГАЦИОННОЙ СИСТЕМЫ В ЭНДОСКОПИЧЕСКОЙ ХИРУРГИИ ОСТЕОМ ЛОБНЫХ ПАЗУХ

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    The article presents the possibility of an electromagnetic navigation system during endoscopic endonasal removal of the frontal sinus osteomas, the possibility of intraoperative monitoring of doing surgery, and postoperative analysis.В статье представлены возможности электромагнитной навигационной системы при эндоскопическом эндоназальном удалении остеомы лобной пазухи, возможности интраоперационного контроля ведения оперативного вмешательства, а также анализ послеоперационных данных

    Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion

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    Axonal injury due to prostatectomy leads to Wallerian degeneration of the cavernous nerve (CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration and reinnervation of the penis. Following CN injury (CNI), RhoA and Rho-associated protein kinase (ROCK) increase in penile endothelial and smooth muscle cells. Previous studies indicate that nerve regeneration is hampered by activation of RhoA/ROCK pathway. We evaluated the role of RhoA/ROCK pathway in CN regulation following CNI using a validated rat model. CNI upregulated gene and protein expression of RhoA/ROCK and caspase-3 mediated apoptosis in the major pelvic ganglion (MPG). ROCK inhibitor (ROCK-I) prevented upregulation of RhoA/ROCK pathway as well as activation of caspase-3 in the MPG. Following CNI, there was decrease in the dimer to monomer ratio of neuronal nitric oxide synthase (nNOS) protein and lowered NOS activity in the MPG, which were prevented by ROCK-I. CNI lowered intracavernous pressure and impaired non-adrenergic non-cholinergic-mediated relaxation in the penis, consistent with ED. ROCK-I maintained the intracavernous pressure and non-adrenergic non-cholinergic-mediated relaxation in the penis following CNI. These results suggest that activation of RhoA/ROCK pathway mediates caspase-3 dependent apoptosis of nitrergic neurons in the MPG following CNI and that ROCK-I can prevent post-prostatectomy ED

    КОМПЬЮТЕРНАЯ ТОМОГРАФИЯ В ДИАГНОСТИКЕ ОСТЕОМ ОКОЛОНОСОВЫХ ПАЗУХ

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    The article presents the possibility of 3D-computer tomography in the diagnosis of the paranasal sinuses osteoma, the results of surgical treatment in 34 patients.В статье представлены возможности 3D-компьютерной томографии в диагностике остеом околоносовых пазух, представлены результаты оперативного лечения у 34 пациентов

    Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

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    The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3% for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table, submitted to European Physical Journal

    Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector

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    The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30

    Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS

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    The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured

    Hunt for new phenomena using large jet multiplicities and missing transverse momentum with ATLAS in 4.7 fb−1 of s√=7TeV proton-proton collisions

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    Results are presented of a search for new particles decaying to large numbers of jets in association with missing transverse momentum, using 4.7 fb−1 of pp collision data at s√=7TeV collected by the ATLAS experiment at the Large Hadron Collider in 2011. The event selection requires missing transverse momentum, no isolated electrons or muons, and from ≥6 to ≥9 jets. No evidence is found for physics beyond the Standard Model. The results are interpreted in the context of a MSUGRA/CMSSM supersymmetric model, where, for large universal scalar mass m 0, gluino masses smaller than 840 GeV are excluded at the 95% confidence level, extending previously published limits. Within a simplified model containing only a gluino octet and a neutralino, gluino masses smaller than 870 GeV are similarly excluded for neutralino masses below 100 GeV

    Evidence for the Higgs-boson Yukawa coupling to tau leptons with the ATLAS detector

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    Results of a search for H → τ τ decays are presented, based on the full set of proton-proton collision data recorded by the ATLAS experiment at the LHC during 2011 and 2012. The data correspond to integrated luminosities of 4.5 fb−1 and 20.3 fb−1 at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV respectively. All combinations of leptonic (τ → `νν¯ with ` = e, µ) and hadronic (τ → hadrons ν) tau decays are considered. An excess of events over the expected background from other Standard Model processes is found with an observed (expected) significance of 4.5 (3.4) standard deviations. This excess provides evidence for the direct coupling of the recently discovered Higgs boson to fermions. The measured signal strength, normalised to the Standard Model expectation, of µ = 1.43 +0.43 −0.37 is consistent with the predicted Yukawa coupling strength in the Standard Model
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