Constitutive Equations for Use in Design Analyses of Long-life Elevated Temperature Components

Design analysis needs and procedures relative to elevated temperature components in liquid metal fast breeder reactor (LMFBR) system were examined. The effects of the thermal transients on the pressure boundary components are enhanced by the excellent heat transfer properties of the liquid sodium coolant. Design criteria for high temperature nuclear reactor components recognize the potential occurrence of inelastic structural response. Specifically, criteria and limits were developed which reflect a recognition of this potential and employ design by analysis concepts that requires that inelastic (elastic-plastic and creep) analyses be performed. Constitutive equations to represent multiaxial time-dependent responses of LMFBR alloys are established. The development of equations applicable under cyclic loading conditions are outlined

In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury.

Microglia respond to damage and microenvironmental changes within the central nervous system by morphologically transforming and migrating to the lesion, but the real-time behavior of populations of these resident immune cells and the neurons they support have seldom been observed simultaneously. Here, we have used in vivo high-resolution optical coherence tomography (OCT) and scanning laser ophthalmoscopy with and without adaptive optics to quantify the 3D distribution and dynamics of microglia in the living retina before and after local damage to photoreceptors. Following photoreceptor injury, microglia migrated both laterally and vertically through the retina over many hours, forming a tight cluster within the area of visible damage that resolved over 2 wk. In vivo OCT optophysiological assessment revealed that the photoreceptors occupying the damaged region lost all light-driven signaling during the period of microglia recruitment. Remarkably, photoreceptors recovered function to near-baseline levels after the microglia had departed the injury locus. These results demonstrate the spatiotemporal dynamics of microglia engagement and restoration of neuronal function during tissue remodeling and highlight the need for mechanistic studies that consider the temporal and structural dynamics of neuron-microglia interactions in vivo

Generation of internal stress and its effects

Internal stresses may be generated continually in many polycrystalline materials. Their existence is manifested by changes in crystal defect concentration and arrangement, by surface observations, by macroscopic shape changes and particularly by alteration of mechanical properties when external stresses are simultaneously imposed

Technical and logistical support for course assessment

Thesis (M.Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2003.Includes bibliographical references (leaf 31).Course assessment is a valuable tool for improving teaching and learning in a class. As part of the course assessment project being started for 6.042 and several other EECS classes, students took diagnostic entry exams and end-of-term surveys in which they were asked to rate themselves on various objectives of the class. I examined this data along with the students' grades, and performed calculations such as finding correlation coefficients to determine what areas of the course might need improvement. After analyzing four semesters of 6.042, it was discovered that the correlation coefficients were not as high as expected. However, the results are still useful in assessing the course, and with several improvements to the current assessment procedure, future results may be more clear.by Simone N. Pugh.M.Eng.and S.B

Properties of quasi-periodic pulsations in solar flares from a single active region

We investigate the properties of a set of solar flares originating from a single active region (AR) that exhibit QPPs, and look for signs of the QPP periods relating to AR properties. The AR studied, best known as NOAA 12192, was unusually long-lived and produced 181 flares. Data from the GOES, EVE, Fermi, Vernov and NoRH observatories were used to determine if QPPs were present in the flares. For the soft X-ray GOES and EVE data, the time derivative of the signal was used. Power spectra of the time series data (without any form of detrending) were inspected, and flares with a peak above the 95% confidence level in the spectrum were labelled as having candidate QPPs. The confidence levels were determined taking account of uncertainties and the possible presence of red noise. AR properties were determined using HMI line of sight magnetograms. A total of 37 flares (20% of the sample) show good evidence of having QPPs, and some of the pulsations can be seen in data from multiple instruments and in different wavebands. The QPP periods show a weak correlation with the flare amplitude and duration, but this may be due to an observational bias. A stronger correlation was found between the QPP period and duration of the QPP signal, which can be partially but not entirely explained by observational constraints. No correlations were found with the AR area, bipole separation, or average magnetic field strength. The fact that a substantial fraction of the flare sample showed evidence of QPPs using a strict detection method with minimal processing of the data demonstrates that these QPPs are a real phenomenon, which cannot be explained by the presence of red noise or the superposition of multiple unrelated flares. The lack of correlation between the QPP periods and AR properties implies that the small-scale structure of the AR is important, and/or that different QPP mechanisms act in different cases.Comment: 23 pages, 57 figures. Accepted for publication by Astronomy & Astrophysic

Three-coordinate iron(II) expanded ring N-heterocyclic carbene complexes

A sterically demanding seven-membered expanded ring N-heterocyclic carbene (NHC) ligand allows access to rare examples of three-coordinate iron(II)-NHC complexes incorporating only halide coligands of the general formula [Fe(NHC)X 2 ] (NHC = 7-DiPP; X = Br (1) Cl (2)). Reducing the steric influence of the ancillary NHC ligand through modulation of the N-aryl substituents leads to either four- or three-coordinate complexes of the general formula [Fe(NHC)Br 2 (THF)] (3) or [Fe(NHC)Br 2 ] (4) (NHC = 7-Mes), dependent upon the solvent of recrystallization. The further reduction of NHC steric influence results in four-coordinate geometries at iron in the form of the dimeric species [Fe(NHC)Br(μ-Br)] 2 (5) or [Fe(NHC)Br 2 (THF)] (6) (NHC = SDiPP), again dependent upon the solvent of recrystallization. Compounds 1-6 have been analyzed by 1 H NMR spectroscopy, X-ray crystallography, elemental microanalysis, Mössbauer spectroscopy (for 1 and 3-5), and Evans method magnetic susceptibility. In addition to these measurements the three-coordinate species 1 and 4 have been further analyzed by SQUID magnetometry and CASSCF calculations, which show significant magnetic anisotropy that is extremely sensitive to the coordination geometry

Learning the Designer's Preferences to Drive Evolution

This paper presents the Designer Preference Model, a data-driven solution that pursues to learn from user generated data in a Quality-Diversity Mixed-Initiative Co-Creativity (QD MI-CC) tool, with the aims of modelling the user's design style to better assess the tool's procedurally generated content with respect to that user's preferences. Through this approach, we aim for increasing the user's agency over the generated content in a way that neither stalls the user-tool reciprocal stimuli loop nor fatigues the user with periodical suggestion handpicking. We describe the details of this novel solution, as well as its implementation in the MI-CC tool the Evolutionary Dungeon Designer. We present and discuss our findings out of the initial tests carried out, spotting the open challenges for this combined line of research that integrates MI-CC with Procedural Content Generation through Machine Learning.Comment: 16 pages, Accepted and to appear in proceedings of the 23rd European Conference on the Applications of Evolutionary and bio-inspired Computation, EvoApplications 202