STWalk: Learning Trajectory Representations in Temporal Graphs

Analyzing the temporal behavior of nodes in time-varying graphs is useful for many applications such as targeted advertising, community evolution and outlier detection. In this paper, we present a novel approach, STWalk, for learning trajectory representations of nodes in temporal graphs. The proposed framework makes use of structural properties of graphs at current and previous time-steps to learn effective node trajectory representations. STWalk performs random walks on a graph at a given time step (called space-walk) as well as on graphs from past time-steps (called time-walk) to capture the spatio-temporal behavior of nodes. We propose two variants of STWalk to learn trajectory representations. In one algorithm, we perform space-walk and time-walk as part of a single step. In the other variant, we perform space-walk and time-walk separately and combine the learned representations to get the final trajectory embedding. Extensive experiments on three real-world temporal graph datasets validate the effectiveness of the learned representations when compared to three baseline methods. We also show the goodness of the learned trajectory embeddings for change point detection, as well as demonstrate that arithmetic operations on these trajectory representations yield interesting and interpretable results.Comment: 10 pages, 5 figures, 2 table

Rothia prosthetic knee joint infection

Rothia species — Gram-positive pleomorphic bacteria that are part of the normal oral and respiratory flora — are commonly associated with dental cavities and periodontal disease although systemic infections have been described. We describe a 53-year-old female with rheumatoid arthritis complicated by prosthetic knee joint infection due to Rothia species, which was successfully treated by surgical removal of prosthesis and prolonged antimicrobial therapy. The issue of antibiotic prophylaxis before dental procedures among patients with prosthetic joint replacements is discussed

Tissue Engineering of the Penis

Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability

Biosensor-based spatial and developmental mapping of maize leaf glutamine at vein-level resolution in response to different nitrogen rates and uptake/assimilation durations

Replicate versus treatment variability of the GlnLux in situ imaging protocol. Three replicates of raw GlnLux agar plate images (Fig. 3) were analysed for each N treatment (+/-) and leaf (1-3) combination (6 plates total per leaf). A 1 x 10-2 M Gln agar disk was also included on each plate for standardization. The ratios of luminescence produced by each standard disk against the GlnLux agar background were pooled to generate SEM and an estimate of plate-to-plate variability. The luminescence output of all three replicates for each N treatment was pooled to generate SEM, and an estimate of the comparative variability due to N uptake/assimilation. Values represent the SEM of 6 plates each. Significant difference at P<0.05 between the variance of the standardization ratio and leaf luminescence is indicated with an asterisk, as determined with F tests. Quantification of luminescence was performed using WinView software (version 2.5.16.5, Princeton Instruments, Trenton, USA). (DOCX 43 kb

Comparative analysis of safety and efficacy of cefotaxime/sulbactam verses piperacillin/tazobactam combinations in the treatment of complicated urinary tract infections

Background: Complicated UTIs (cUTIs) are leading causes of the gram negative bacteraemia. The objective of this study was to compare efficacy and safety Cefotaxime/ Sulbactam (CTS) and Piperacillin/ Tazobactam (PT) combinations in complicated Urinary Tract Infections.Methods: Total 80 patients admitted in the hospital due to cUTI were enrolled. 31 patients were given CTS while 49 patients were given PT. Clinical symptoms were registered and scored as mild (1) moderate (2) or severe (3). The follow-up of were done daily till the patient is discharged. Thereafter, one follow up visit was done within 4 to 9 days of after discharge, termed as test of cure (TOC), and, one late follow up visit after 6 to 8 weeks was done, known as late follow up visit (LFU). Clinical assessments and microbiological analysis were done at the time of TOC and LFU.Results: At TOC visit, in CTS and PT groups, clinical scores were 1.25±3.47 and 0.86±2.35, respectively (p<0.005). Rate of clinical improvement at TOC visit was 92.00% and 92.68% while microbiological clearance was 84.00% and 87.80% with CTS and PT groups respectively. At LFU visit, clinical scores CTS and PT in groups were 1.30±3.56 and 1.32±3.37, respectively, suggesting significant improvement from baseline (p<0.005). Clinical cure rate at LFU visit was 88.00% and 87.80% while microbiological cure rate at LFU visit was 76.00% and 82.91% in CTS and PT groups respectively.Conclusions: Results suggest that both regimens have no significant difference for the treatment of cUTI. CTS and PT both are equally efficacious in treatment of cUTI

Dynamics of top-down factors with relation to ecological attributes of an endangered species Commiphora wightii

Present study was aimed to explore the influence of top down factors on ecological attributes of Commiphora wightii collected from seven districts of arid and semi arid parts of the Rajasthan. Ecological variables in respect of 46 accessions of this species were quantified. To assess the explanatory factors governing quantified ecological variables, soil samples were collected to analyze soil texture, soil EC, pH, available potassium, available phosphorus and total soil nitrogen. Results showed that there was a specific relationship between soil variables and occurence of C. wightii. The mid ranges of potassium (200-300 kg/ha) emerged as favourable to have better density and health of C. wightii: This is the first report on regulatory role of potassium on distribution and occurrence of C. wightii

Awareness and impact of educational intervention regarding kangaroo mother care among pediatricians of Marathwada region of Maharashtra

Objective: The objective of the study was to compare knowledge and attitudes toward kangaroo mother care (KMC) among pediatric practitioners in Marathwada region before and after a workshop on KMC. Material and Methods: A prospective comparative study was conducted among 40 pediatricians practising in the rural area of Marathwada region. Clinicians having at least Level 2 neonatal intensive care unit setup at their place were enrolled in the study. Every pediatrician satisfying the selection criteria and willing to participate was enrolled in the study. They were given a questionnaire, consisting 25 questions, which were supposed to be answered at the time of enrolment, i.e., pre-test. After that, the participant was given a short booklet on KMC to read, and then after a gap of 7 days, the participant attended a workshop on KMC for 4 h, in which details regarding KMC, advantages of KMC, and videos showing actual practice of KMC were shown to participants. After completion of workshop, participants were given the same questionnaire and pre- and post-test scores were calculated. Results: The mean score in basic knowledge was 2