58 research outputs found

    A time-frequency approach to blind deconvolution in multipath underwater channels

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    Blind deconvolution is presented in the underwater acoustic channel context, by time-frequency processing. The acoustic propagation environment was modelled as a multipath propagation channel. For noiseless simulated data, source signature estimation was performed by a model-based method. The channel estimate was obtained via a time-frequency formulation of the conventional matched-filter. Simulations used a ray-tracing physical model, initiated with at-sea recorded environmental data, in order to produce realistic underwater channel conditions. The quality of the estimates was 0.793 for the source signal, and close to I for the resolved amplitudes and time-delays of the impulse response. Time-frequency processing has proved to overcome the typical ill-conditioning of single sensor deterministic deconvolution techniques

    ILC Beam Energy Measurement by means of Laser Compton Backscattering

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    A novel, non-invasive method of measuring the beam energy at the International Linear Collider is proposed. Laser light collides head-on with beam particles and either the energy of the Compton scattered electrons near the kinematic end-point is measured or the positions of the Compton backscattered γ\gamma-rays, the edge electrons and the unscattered beam particles are recorded. A compact layout for the Compton spectrometer is suggested. It consists of a bending magnet and position sensitive detectors operating in a large radiation environment. Several options for high spatial resolution detectors are discussed. Simulation studies support the use of an infrared or green laser and quartz fiber detectors to monitor the backscattered photons and edge electrons. Employing a cavity monitor, the beam particle position downstream of the magnet can be recorded with submicrometer precision. Such a scheme provides a feasible and promising method to access the incident beam energy with precisions of 10−410^{-4} or better on a bunch-to-bunch basis while the electron and positron beams are in collision.Comment: 47 pages, 26 figures, version as accepted by Nucl. Instr. Meth. A after improvement

    Apolipoprotein C3 Polymorphisms, Cognitive Function and Diabetes in Caribbean Origin Hispanics

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    Apolipoprotein C3 (APOC3) modulates triglyceride metabolism through inhibition of lipoprotein lipase, but is itself regulated by insulin, so that APOC3 represents a potential mechanism by which glucose metabolism may affect lipid metabolism. Unfavorable lipoprotein profiles and impaired glucose metabolism are linked to cognitive decline, and all three conditions may decrease lifespan. Associations between apolipoprotein C3 (APOC3) gene polymorphisms and impaired lipid and glucose metabolism are well-established, but potential connections between APOC3 polymorphisms, cognitive decline and diabetes deserve further attention.We examined whether APOC3 single nucleotide polymorphisms (SNPs) m482 (rs2854117) and 3u386 (rs5128) were related to cognitive measures, whether the associations between cognitive differences and genotype were related to metabolic differences, and how diabetes status affected these associations. Study subjects were Hispanics of Caribbean origin (n = 991, aged 45-74) living in the Boston metropolitan area.Cognitive and metabolic measures differed substantially by type II diabetes status. In multivariate regression models, APOC3 m482 AA subjects with diabetes exhibited lower executive function (P = 0.009), Stroop color naming score (P = 0.014) and Stroop color-word score (P = 0.022) compared to AG/GG subjects. APOC3 m482 AA subjects with diabetes exhibited significantly higher glucose (P = 0.032) and total cholesterol (P = 0.028) compared to AG/GG subjects. APOC3 3u386 GC/GG subjects with diabetes exhibited significantly higher triglyceride (P = 0.004), total cholesterol (P = 0.003) and glucose (P = 0.016) compared to CC subjects.In summary, we identified significant associations between APOC3 polymorphisms, impaired cognition and metabolic dysregulation in Caribbean Hispanics with diabetes. Further research investigating these relationships in other populations is warranted

    In vitro studies and preliminary in vivo evaluation of silicified concentrated collagen hydrogels

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    Hybrid and nanocomposite silicacollagen materials derived from concentrated collagen hydrogels were evaluated in vitro and in vivo to establish their potentialities for biological dressings. Silicification significantly improved the mechanical and thermal stability of the collagen network within the hybrid systems. Nanocomposites were found to favor the metabolic activity of immobilized human dermal fibroblastswhile decreasing the hydrogel contraction. Cell adhesion experiments suggested that in vitro cell behavior was dictated by mechanical properties and surface structure of the scaffold. First-to-date in vivo implantation of bulk hydrogels in subcutaneous sites of rats was performed over the vascular inflammatory period. These materials were colonized and vascularized without inducing strong inflammatory response. These data raise reasonable hope for the future application of silicacollagen biomaterials as biological dressings.Fil: Desimone, Martín Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fårmaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fårmaco; ArgentinaFil: Hélary, Christophe. Université Pierre et Marie Curie; FranciaFil: Quignard, Sandrine. Université Pierre et Marie Curie; FranciaFil: Rietveld, Ivo B. Universite de Paris; FranciaFil: Bataille, Clement. Université de Versailles Saint-quentin-en-yvelines.; FranciaFil: Copello, Guillermo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fårmaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fårmaco; ArgentinaFil: Mosser, Gervaise. Université Pierre et Marie Curie; FranciaFil: Giraud Guille, Marie-Madeleine. Université Pierre et Marie Curie; FranciaFil: Livage, Jacques. Université Pierre et Marie Curie; FranciaFil: Meddahi Pellé, Anne. Université de Versailles Saint-quentin-en-yvelines.; FranciaFil: Coradin, Thibaud. Université Pierre et Marie Curie; Franci

    Cuidados biomĂ©dicos de saĂșde em Angola e na Companhia de Diamantes de Angola, c. 1910-1970

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    Pretende-se caracterizar a prestação de cuidados biomĂ©dicos em Angola durante a atividade da Companhia de Diamantes de Angola. Uma anĂĄlise comparativa de polĂ­ticas e prĂĄticas de saĂșde pĂșblica de vĂĄrios atores coloniais, como os serviços de saĂșde da Companhia, sua congĂ©nere do Estado e outras empresas coloniais, revelarĂĄ diferenças de investimento na saĂșde, isto Ă©, instalaçÔes e pessoal de saĂșde, e tratamentos. Este escrutĂ­nio bem como as condiçÔes de vida iluminarĂŁo o carĂĄcter idiossincrĂĄtico e central dos serviços de saĂșde da Companhia em termos de morbimortalidade em Angola, e a centralidade destes para as representaçÔes de um impĂ©rio cuidador

    Time-frequency approach to the study of underwater acoustic channel estimation and source reconstruction

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    This communication presents a pre-processing scheme possibly included in the global methodology of passive tomography, in an underwater acoustic channel

    Blind separation of underwater acoustic signals

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    Abstract. In last two decades, many researchers have been involved in acoustic tomography applications. Recently, few algorithms have been dedicated to the passive acoustic tomography applications in a single input single output channel. Unfortunately, most of these algorithms can not be applied in a real situation when we have a Multi-Input Multi-Output channel. In this paper, we propose at first a realistic model of an underwater acoustic channel, then a general structure to separate acoustic signals crossing an underwater channel is proposed. Concerning ICA algorithms, many algorithms have been implemented and tested but only two algorithms give us good results. The latter algorithms minimize two different second order statistic criteria in the frequency domain. Finally, some simulations have been presented and discussed. KEY WORD: Underwater acoustic applications, passive acoustic Tomography, second order statistics in frequency domain, multipath channel, sparseness or non-stationary signals.

    Time-frequency approach to multipath underwater channel deconvolution

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    Blind deconvolution is presented in the underwater acoustic channel context, by time-frequency processing. The acoustic propagation environment was modelled as a multipath propagation channel. For noiseless simulated data, source signature estimation was performed by a model-based method. The channel estimate was obtained via a time-frequency formulation of the conventional matched-filter. Simulations used a ray-tracing physical model, initiated with at-sea recorded environmental data, in order to produce realistic underwater channel conditions. The quality of the estimates was 0.793 for the source signal, and close to 1 for the resolved amplitudes and time-delays of the impulse response. Time-frequency processing has proved to overcome the typical ill-conditioning of single sensor deterministic deconvolution techniques.MCT, FCT, PRAXIS XX
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