2,911 research outputs found

    Teacher Perceptions of an Online Extensive Reading Platform

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    Extensive reading (ER) has been shown to have a number of positive effects on learning a foreign language. Improvements in vocabulary size, reading fluency and comprehension, and grammatical accuracy are just some of the outcomes of extensive reading programs. Since 2011, extensive reading at Sojo University has been carried out through the use of graded readers, typically in the form of physical books made available to students either in class or through the Self-Access Learning Center (SALC). Recently, the popularity of reading texts in digital format has increased with the ubiquitous ownership of portable devices such as smartphones, tablets, and lightweight laptops. In April 2018, all second-year students at Sojo University were required to purchase a subscription to a website known as Xreading (www.xreading.com), which offers hundreds of graded readers in digital format. This study examines teacher perceptions of the platform. A total of nine teachers participated in the study, including the authors of the paper, and the results appear to indicate that teachers feel extensive reading in general is a worthwhile activity but difficult to implement in this context. Results also show that teachers feel the online platform, Xreading, needs to improve in several areas before providing a significant advantage over physical books

    CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data

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    SUMMARY: The current methods available to detect chromosomal abnormalities from DNA microarray expression data are cumbersome and inflexible. CAFE has been developed to alleviate these issues. It is implemented as an R package that analyzes Affymetrix *.CEL files, and comes with flexible plotting functions, easing visualization of chromosomal abnormalities. AVAILABILITY: CAFE is available from https://bitbucket.org/cob87icW6z/cafe/ as both source and compiled packages for Linux and Windows. It is released under the GPL version 3 license. CAFE will also be freely available from Bioconductor. CONTACT: [email protected], [email protected]

    Correlating Pedestrian Flows and Search Engine Queries

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    An important challenge for ubiquitous computing is the development of techniques that can characterize a location vis-a-vis the richness and diversity of urban settings. In this paper we report our work on correlating urban pedestrian flows with Google search queries. Using longitudinal data we show pedestrian flows at particular locations can be correlated with the frequency of Google search terms that are semantically relevant to those locations. Our approach can identify relevant content, media, and advertisements for particular locations.Comment: 4 pages, 1 figure, 1 tabl

    How to Educate Entrepreneurs?

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    Entrepreneurship education has two purposes: To improve studentsā€™ entrepreneurial skills and to provide impetus to those suited to entrepreneurship while discouraging the rest. While entrepreneurship education helps students to make a vocational decision its effects may conflict for those not suited to entrepreneurship. This study shows that vocational and the skill formation effects of entrepreneurship education can be identified empirically by drawing on the Theory of Planned Behavior. This is embedded in a structural equation model which we estimate and test using a robust 2SLS estimator. We find that the attitudinal factors posited by the Theory of Planned Behavior are positively correlated with studentsā€™ entrepreneurial intentions. While conflicting effects of vocational and skill directed course content are observed in some individuals, overall these types of content are complements. This finding contradicts previous results in the literature. We reconcile the conflicting findings and discuss implications for the design of entrepreneurship courses

    Production of human recombinant proapolipoprotein A-I in Escherichia coli: purification and biochemical characterization

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    A human liver cDNA library was used to isolate a clone coding for apolipoprotein A-I (Apo A-I). The clone carries the sequence for the prepeptide (18 amino acids), the propeptide (6 amino acids), and the mature protein (243 amino acids). A coding cassette for the proapo A-I molecule was reconstructed by fusing synthetic sequences, chosen to optimize expression and specifying the amino-terminal methionine and amino acids -6 to +14, to a large fragment of the cDNA coding for amino acids 15-243. The module was expressed in pOTS-Nco, an Escherichia coli expression vector carrying the regulatable X P^ promoter, leading to the production of proapolipoprotein A-I at up to 10% of total soluble proteins. The recombinant polypeptide was purified and characterized in terms of apparent molecular mass, isoelectric point, and by both chemical and enzymatic peptide mapping. In addition, it was assayed in vitro for the stimulation of the enzyme lecithin: cholesterol acyltransferase. The data show for the first time that proapo A-I can be produced efficiently in E. coli as a stable and undegraded protein having physical and functional properties indistinguishable from those of the natural product

    Ranking Spaces for Predicting Human Movement in an Urban Environment

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    A city can be topologically represented as a connectivity graph, consisting of nodes representing individual spaces and links if the corresponding spaces are intersected. It turns out in the space syntax literature that some defined topological metrics can capture human movement rates in individual spaces. In other words, the topological metrics are significantly correlated to human movement rates, and individual spaces can be ranked by the metrics for predicting human movement. However, this correlation has never been well justified. In this paper, we study the same issue by applying the weighted PageRank algorithm to the connectivity graph or space-space topology for ranking the individual spaces, and find surprisingly that (1) the PageRank scores are better correlated to human movement rates than the space syntax metrics, and (2) the underlying space-space topology demonstrates small world and scale free properties. The findings provide a novel justification as to why space syntax, or topological analysis in general, can be used to predict human movement. We further conjecture that this kind of analysis is no more than predicting a drunkard's walking on a small world and scale free network. Keywords: Space syntax, topological analysis of networks, small world, scale free, human movement, and PageRankComment: 11 pages, 5 figures, and 2 tables, English corrections from version 1 to version 2, major changes in the section of introduction from version 2 to

    Penning traps as a versatile tool for precise experiments in fundamental physics

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    This review article describes the trapping of charged particles. The main principles of electromagnetic confinement of various species from elementary particles to heavy atoms are briefly described. The preparation and manipulation with trapped single particles, as well as methods of frequency measurements, providing unprecedented precision, are discussed. Unique applications of Penning traps in fundamental physics are presented. Ultra-precise trap-measurements of masses and magnetic moments of elementary particles (electrons, positrons, protons and antiprotons) confirm CPT-conservation, and allow accurate determination of the fine-structure constant alpha and other fundamental constants. This together with the information on the unitarity of the quark-mixing matrix, derived from the trap-measurements of atomic masses, serves for assessment of the Standard Model of the physics world. Direct mass measurements of nuclides targeted to some advanced problems of astrophysics and nuclear physics are also presented

    Irritability and parenting practices as mediational variables between temperament and affective, anxiety, and oppositional defiant problems

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    Irritability and parenting are potential targets for transdiagnostic studies to identify the common and core dysfunctional characteristics underlying several diagnostic pictures with the goal of addressing these issues in treatment. Our objective was to investigate the different paths from temperament to child psychopathology (affective, anxiety, and oppositional problems) through irritability and parenting using a prospective design from ages 3 to 7. A sample of 614 3-year-old preschoolers was followed at ages 4, 6, and 7. Parents answered questionnaires about temperament (age 3), irritability (age 4), parenting practices (age 6), and psychopathology (age 7). Statistical analyses were carried out through structural equation modeling (SEM) to test the mediation effect of irritability and parenting practices from temperament (negative affectivity and effortful control) through to affective, anxious, and oppositional problems. The proposed model fit the data well. SEM showed (a) an indirect effect from temperament to affective problems, via irritability and positive parenting; (b) a direct effect from negative affectivity to anxiety, plus an indirect effect from both temperament dimensions, via irritability and autonomy parenting practices; and (c) an indirect effect from temperament to oppositional problems, via irritability and punitive parenting. Irritability and parenting are transdiagnostic mediational variables that should be focused on in intervention programs for affective, anxiety, and oppositional problem
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