Infectious bursal disease: evaluation of pathogenicity of commercial vaccines from Brazil in specific pathogen free chichens

Infectious Bursal Disease (IBD) is a chicken disease economically important for the poultry industry in function of the immune depression that it causes. Disease control is made with different vaccines and vaccination programs. In present work, the pathogenicity of 3 intermediate vaccines (I1, I2 and I3), 2 intermediate more pathogenic (IP1 and IP2) and 3 vaccines containing strong virus (F1, F2 and F3) was evaluated. Birds vaccinated with IP1, IP2, F1, F2 and F3 showed significantly lower bursa size in relation to control animals and animals vaccinated with I1, I2 and I3. On the other hand, vaccines I1 and I3 induced antibody titers higher than the control and lower than I2, IP1, IP2, F1, F2 and F3. Histological scores showed that vaccines I1, I2 and I3 induced similar injury degree, although I2 and I3 were not different from the control, whereas I1 was slightly different. Strong vaccines induced more pronounced lesions than the other tested vaccines. These findings suggest that strong vaccines are able to cause severe bursal injuries. However, bursometry and relative weight of the bursa of Fabricius were considered inadequate to evaluate vaccine pathogenicity. Moreover, strong vaccines induced higher antibody titers than the other vaccines, although some intermediate vaccines induced similar titers

Enhanced Poleward Moisture Transport and Amplified Northern High-Latitude Wetting Trend

Observations and climate change projections forced by greenhouse gas emissions have indicated a wetting trend in northern high latitudes, evidenced by increasing Eurasian Arctic river discharges1, 2, 3. The increase in river discharge has accelerated in the latest decade and an unprecedented, record high discharge occurred in 2007 along with an extreme loss of Arctic summer sea-ice cover4, 5, 6. Studies have ascribed this increasing discharge to various factors attributable to local global warming effects, including intensifying precipitation minus evaporation, thawing permafrost, increasing greenness and reduced plant transpiration7, 8, 9, 10, 11. However, no agreement has been reached and causal physical processes remain unclear. Here we show that enhancement of poleward atmospheric moisture transport (AMT) decisively contributes to increased Eurasian Arctic river discharges. Net AMT into the Eurasian Arctic river basins captures 98% of the gauged climatological river discharges. The trend of 2.6% net AMT increase per decade accounts well for the 1.8% per decade increase in gauged discharges and also suggests an increase in underlying soil moisture. A radical shift of the atmospheric circulation pattern induced an unusually large AMT and warm surface in 2006–2007 over Eurasia, resulting in the record high discharge