29 research outputs found
Eine kritische Betrachtung des Spannungsfeldes von Regulierung und Liberalismus im Privatrecht am Beispiel der branchenübergreifenden Legalitätskontrollpflicht
Die Arbeit untersucht die branchenübergreifende Legalitätskontrollpflicht für Unternehmen, insbesondere im Gesellschaftsrecht. Ausgangspunkt ist die These, dass sich anhand der Entwicklungsstränge der Legalitätskontrolle seit einigen
Jahrzehnten ein (innovativer) Wandel der staatlichen regulativen Struktur beobachten lässt, für den hier der Begriff des „regulativen Kapitalismus” benutzt wird. Gleichzeitig soll gezeigt werden, dass dieser Strukturwandel im Privatrecht mit einem liberalen Grundverständnis zusammenstößt. Dieses Grundverständnis soll kritisch und insbesondere kulturtheoretisch rekonstruiert und einem demokratischen Privatrechtsverständnis entgegengestellt werden
The Advancement of Biomaterials in Regulating Stem Cell Fate.
Stem cells are well-known to have prominent roles in tissue engineering applications. Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can differentiate into every cell type in the body while adult stem cells such as mesenchymal stem cells (MSCs) can be isolated from various sources. Nevertheless, an utmost limitation in harnessing stem cells for tissue engineering is the supply of cells. The advances in biomaterial technology allows the establishment of ex vivo expansion systems to overcome this bottleneck. The progress of various scaffold fabrication could direct stem cell fate decisions including cell proliferation and differentiation into specific lineages in vitro. Stem cell biology and biomaterial technology promote synergistic effect on stem cell-based regenerative therapies. Therefore, understanding the interaction of stem cell and biomaterials would allow the designation of new biomaterials for future clinical therapeutic applications for tissue regeneration. This review focuses mainly on the advances of natural and synthetic biomaterials in regulating stem cell fate decisions. We have also briefly discussed how biological and biophysical properties of biomaterials including wettability, chemical functionality, biodegradability and stiffness play their roles
Condensed description of the manufacture of beet sugar,
Mode of access: Internet
Concise Review: Asymmetric Cell Divisions in Stem Cell Biology
Somatic stem cells are rare cells with unique properties residing in many organs and tissues. They are undifferentiated cells responsible for tissue regeneration and homeostasis, and contain both the capacity to self-renew in order to maintain their stem cell potential and to differentiate towards tissue-specific, specialized cells. However, the knowledge about the mechanisms controlling somatic stem cell fate decisions remains sparse. One mechanism which has been described to control daughter cell fates in selected somatic stem cell systems is the process of asymmetric cell division (ACD). ACD is a tightly regulated and evolutionary conserved process allowing a single stem or progenitor cell to produce two differently specified daughter cells. In this concise review, we will summarize and discuss current concepts about the process of ACD as well as different ACD modes. Finally, we will recapitulate the current knowledge and our recent findings about ACD in human hematopoiesis