Low Power Reversible Parallel Binary Adder/Subtractor

In recent years, Reversible Logic is becoming more and more prominent technology having its applications in Low Power CMOS, Quantum Computing, Nanotechnology, and Optical Computing. Reversibility plays an important role when energy efficient computations are considered. In this paper, Reversible eight-bit Parallel Binary Adder/Subtractor with Design I, Design II and Design III are proposed. In all the three design approaches, the full Adder and Subtractors are realized in a single unit as compared to only full Subtractor in the existing design. The performance analysis is verified using number reversible gates, Garbage input/outputs and Quantum Cost. It is observed that Reversible eight-bit Parallel Binary Adder/Subtractor with Design III is efficient compared to Design I, Design II and existing design.Comment: 12 pages,VLSICS Journa

Secured Smart Healthcare Monitoring System Based on Iot

Technology plays the major role in healthcare not only for sensory devices but also in communication, recording and display device. It is very important to monitor various medical parameters and post operational days. Hence the latest trend in Healthcare communication method using IOT is adapted. Internet of things serves as a catalyst for the healthcare and plays prominent role in wide range of healthcare applications. In this project the PIC18F46K22 microcontroller is used as a gateway to communicate to the various sensors such as temperature sensor and pulse oximeter sensor. The microcontroller picks up the sensor data and sends it to the network through Wi-Fi and hence provides real time monitoring of the health care parameters for doctors. The data can be accessed anytime by the doctor. The controller is also connected with buzzer to alert the caretaker about variation in sensor output. But the major issue in remote patient monitoring system is that the data as to be securely transmitted to the destination end and provision is made to allow only authorized user to access the data. The security issue is been addressed by transmitting the data through the password protected Wi-Fi module ESP8266 which will be encrypted by standard AES128 and the users/doctor can access the data by logging to the html webpage. At the time of extremity situation alert message is sent to the doctor through GSM module connected to the controller. Hence quick provisional medication can be easily done by this system. This system is efficient with low power consumption capability, easy setup, high performance and time to time response. DOI: 10.17762/ijritcc2321-8169.150712

Study of wear test on hybrid material reinforced Epoxy based Composites

In the present work, the hybrid nanomaterial such as Graphene – Multiwalled carbon nanotube reinforced epoxy composites are fabricated with dif ferent weight fraction of the reinforcement and are subjected to wear test. The mechanical properties of these composites are investigated and found posses decrease in wear rate, as the increased in weight fraction of the reinforcement there is reducing wear rate compared to the based matrix fabricated using the same process

Pycnodysostosis: a distinctive brittle bone disease?

Pycnodysostosis is a rare disorder that is inherited as an autosomal recessive trait usually diagnosed at an early age with an estimated incidence of 1.7 per 1 million births. It is a rare clinical entity, first described in 1962 by Maroteaux and Lamy. The disease has also been named Toulouse-Lautrec syndrome, after the French artist Henri de Toulouse-Lautrec, who suffered from the disease. Pycnodysostosis is a lysosomal storage disorder of the bone caused by a mutation in the gene that codes the enzyme Cathepsin K causing osteosclerosis. However, the diagnosis is sometimes late, made as a result of bone fracture, given the severe bone fragility resulting from increased bone density. Oral and maxillofacial manifestations of this disease are very common

Comparitive study of clinical effect of Apamarga Kshara Sutra prepared by 7 and 21 coatings in Bhagandara

Background: Bhagandara is a 2nd highest prevalent disease among the anorectal diseases. It can be correlated to Fistula-In-Ano. For the management of fistula in ano various surgical, parasurgical and minimally invasive surgical procedures have been mentioned. But all these procedures carry a disadvantage of high rates of recurrence and also have a great chance of creation of serious complications like anal incontinence and anal stenosis. Hence the search for a newer, safer and scientific treatment for the management of this disease continues. Objectives: A new Kshara Sutra with fewer coatings has been tried to see if results are the same with an advantage of early and easy preparation. Materials and Methods: Total 30 patients were randomly selected in the study and divided into 2 groups fulfilling the inclusion criteria which were designed for the study. Results: Study showed significant results in reducing the discharge, pain, itching and burning sensation and induration within the group and insignificant result obtained between the groups statistically. Conclusion: The study revealed that Kshara Sutra prepared with 7 coating is more economical, easy to prepare and equally efficient in the management of Bhagandara

Fracture Simulation of Concrete Beams to assess softening behavior by varying different fractions of Aggregates

Simulating the concrete fracture unlike other elastic and brittle materials quite different due to its quasibrittleness. The present research focussed on assess softening behavior by varying different fractions of aggregates  and cement matrix in micro details. Extended Finite Element Method (XFEM) for crack modeling implemented for simulating and visualizing crack propagation through Cement matrix, Interfacial Transition Zone (ITZ) and Aggregates . This approach permits the initializing crack by from enrichment zone and propagation of crack through element by traction separation law .The crack formation initiates when the maximum principal tensile stress reaches the tensile strength. The work involves creating python script for iterative process of random distribution of aggregates with in the matrix using Monte Carlo method and creating Cohesive zone element for zero thickness ITZ. introduces a finite element modeling technique for investigating multiscale fracture characteristics. This approach encompasses multiple levels of analysis, including the generation of aggregate particles using a Monte Carlo method implemented via a Python script. Additionally, we replicate the Interfacial Transition Zone (ITZ) between aggregate and mortar in the model. The load-deflection curves can be used to assess the softening behavior of concrete and suggest the realistic fraction of coarse aggregate in mix proportion to impart more ductility to beams

Effect of feeding concentrates of Lactobacillus organisms on intestinal colonization by Escherichia coli in swine

A Lactobacillus species of human intestinal origin (strain MLC) used in swine feeding experiments was characterized using biochemical, genetic and serological techniques and found to be Lactobacillus lactis. Bottle feeding of the MLC strain in concentrate form (> 10⁹ cfu/ml) resulted in a reduction in both fecal coliforms and the incidence of scouring. In one group of pigs which received concentrate for 54 days, the Lactobacillus to coliform ratio was 1280:1; in the control group the ratio was 2.3:1. To increase the sample size, a herd of 125 swine was fed concentrates of Lactobacillus lactis MLC through the drinking water system using a water proportioner. After 90 days of such treatment, the coliform counts were reduced by 95%. The scouring incidence in the treated pigs was 13% as compared to 35% in the control group. However numbers of fecal lactobacilli were not increased. The influence of Lactobacillus MLC feeding on the bacterial flora of different parts of gastrointestinal tract was studied. In the case of scouring pigs, enteropathogenic Escherichia coli (EEC) were present in larger numbers in the tissue homogenate of different parts of the tract than in the lumen. The virulence of the EEC found present was confirmed by experimental infection in pigs. In control, non-scouring pigs only non-EEC were found in the tissue. In Lactobacillus MLC-fed pigs, E. coli both in the tissue and lumen was reduced to low numbers; also, the few E. coli observed were non-enteropathogenic. Thus by feeding Lactobacillus MLC concentrate, it was possible to reduce the E. coli to less than 10² /gm There were higher numbers of lactobacilli in the tissues of Lactobacillus-fed pigs than in control and scouring pigs. The lactobacilli isolated from tissue homogenate of the treated animals resembled biochemically and serologically (fluorescent antibody staining) the Lactobacillus MLC which was fed. Histological studies were done to show direct evidence of colonization in frozen sections of intestine obtained from Lactobacillus MLC-fed pigs. Gram and toluidine blue-staining revealed large numbers of Gram-positive bacilli colonizing the surface epithelium of the villi. On the other hand, control pigs which died of scouring revealed many EEC colonizing the small intestine. Pigs in groups receiving colostrum and lactobacilli performed very well. No symptoms of diarrhea was seen and many lactobacilli colonized throughout the small intestine. Even after the challenge with EEC serotype 09:K:NM, these two groups of pigs did not show any signs of disease and very few EEC colonized the intestines even after the challenge. Pigs not receiving colostrum but only lactobacilli did not scour before challenge with EEC 09:K:NM and many lactobacilli colonized the small intestine. However, 72 hours after challenge these latter animals revealed symptoms of diarrhea and EEC were seen colonizing the small intestine in addition to lactobacilli. The possible role of surface antigens in colonization by lactobacilli was studied. Data revealed that Lactobacillus lactis MLC and L. salivarius did not have any antigens in common. On the other hand, Lactobacillus FHS isolated from pig intestine had three antigens in common with the MLC strain. However, in vivo tests showed that all three strains colonized the small intestine to the same degree. This indicated that surface antigens were not involved in the colonization mechanism. The ability of Lactobacillus MLC to inhibit a variety of intestinal pathogens in broth cultures was demonstrated. Organisms inhibited included E. coli, Staphylococcus aureus, Clostridium perfringens and Bacterotdes sp. The mechanism of inhibition of S. aureus and E. coli in milk and broth was examined. These organisms did not grow in cell-free culture supernatants (whey at pH 4.0) after growth of the Lactobacillus MLC but they grew well in broth adjusted to pH 4.0 Supernatant from cultures of Lactobacillus MLC concentrate was found to contain 2-Deoxy-D-glucose in addition to glucose and galactose. Studies using 2-Deoxy-D-glucose alone and with glucose and galactose showed that the former was inhibitory to E. coli, S. aureus and Salmonella typhimurium. Possible applications of these findings in the animal industry as a substitute to antibiotics are discussed. A greater use of Lactobacillus organisms in preventive treatment of intestinal diseases is suggested

Effect of post harvest ripening on bioactive secondary metabolites and antioxidant activity in mango cv. Amrapali

Mango possesses many bioactive phytonutrients at ripe stage which boost our immune systemagainst many diseases. Post harvest ripening plays a major role in changes in those bioactivephytochemicals and their antioxidant activity. Hence, the present study was undertaken toassess the changes in bioactive phytonutrients and total antioxidant activity during ripeningof mango cv. Amrapali. The fruits were analyzed for total antioxidants, total phenols, totalflavonoids and total carotenoids from the day of harvest to its deterioration. Fruit peel andpulp color was measured with SPH850 spectrophotometer on the basis of the CIE LAB colorsystem (L*, a* and b*). The results revealed that total phenols (36.11 to 66.53mg GAE 100g-1),total flavonoids (14.33 to 34.67mg QE 100g-1), total carotenoids (2.23 to 11.47mg 100g-1) andtotal antioxidant (0.37 to 0.76 mmol Trolox 100g-1) activity increased gradually from day one toninth day after harvest and decreased slightly thereafter up to eleventh day of harvest excepttotal carotenoids, which remained constant. Strong correlations between total phenols (0.94),total flavonoids (0.86) and total carotenoids (0.97) with total antioxidant activity were noticed.Positive relationship between total carotenoids and L*, a*, b* values in mango peel and pulpduring ripening was also observed. It can be concluded that ripening affected the compositionof bioactive phytonutrients and their antioxidant activity in mango andmaximum nutraceuticalscontents were noticed from seven to nine days after harvest