2,345 research outputs found
Dynamic load capacities of graphite fiber: Polyimide composites in oscillating plain bearings to 340 C (650 F)
Load capacities were determined for plain spherical bearings with self-lubricating spherical elements of graphite-fiber-reinforced-polyimide, and for plain cylindrical bearings with thin-wall liners of the composite in the bearing bores. Composites consisted of a 1-to-1 weight ratio of graphite fibers and polyimide. Oscillation was at an amplitude of + or - 15 deg at a frequency of 1 hertz. Bearings with composite ball material had a load capacity of approximately 69 MN/sq m (10 000 psi) at room temperature 25 MN/sq m (3600 psi) at 340 C (650 F). Bearings with thin-wall composite liners had much higher load capacities of 280 MN/sq m (40 000 psi) at room temperature amd 240 MN/sq m (35 000 psi) at 320 C (600 F). Friction coefficients were in the range of 0.12 to 0.19. The addition of 10 wt.% graphite fluoride solid lubricant to the composition of the thin-wall liners reduced friction coefficients into the range of 0.10 to 0.12
Arthritis Is Developed in Borrelia-Primed And -Infected Mice Deficient of Interleukin-17
Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutralization of IL-17 with antibodies inhibits induction of arthritis in Borrelia-primed and -infected C57BL/6 wild-type mice. We hypothesized that mice lacking IL-17 would fail to develop Borrelia-induced arthritis. IL-17-deficient and wild-type C57BL/6 mice were primed with heat-inactivated Borrelia and then infected with viable spirochetes 3 weeks later. No swelling or major histopathological changes of the hind paws were detected in IL-17-deficient or wild-type mice that were primed with Borrelia or infected with viable spirochetes. By contrast, IL-17-deficient and wild-type mice that were primed and subsequently infected with heterologous Borrelia developed severe swelling and histopathological changes of the hind paws. In addition, Borrelia-primed and -infected IL-17-deficient mice exhibited elevated gamma-interferon (IFN-γ) levels in sera and increased frequencies of IFN-γ-expressing lymphocytes in popliteal lymph nodes compared to Borrelia-primed and -infected wild-type mice. These results demonstrate that IL-17 is not required for development of severe pathology in response to infection with Borrelia burgdorferi, but may contribute to disease through an interaction with IFN-γ
Automated data pre-processing via meta-learning
The final publication is available at link.springer.comA data mining algorithm may perform differently on datasets with different characteristics, e.g., it might perform better on a dataset with continuous attributes rather than with categorical attributes, or the other way around.
As a matter of fact, a dataset usually needs to be pre-processed. Taking into account all the possible pre-processing operators, there exists a staggeringly large number of alternatives and nonexperienced users become overwhelmed.
We show that this problem can be addressed by an automated approach, leveraging ideas from metalearning.
Specifically, we consider a wide range of data pre-processing techniques and a set of data mining algorithms. For each data mining algorithm and selected dataset, we are able to predict the transformations that improve the result
of the algorithm on the respective dataset. Our approach will help non-expert users to more effectively identify the transformations appropriate to their applications, and hence to achieve improved results.Peer ReviewedPostprint (published version
Estimating Winning Probabilities in Backgammon Races
In modern backgammon, it is advantageous to know the chances each player has of winning, and to be able to compute the chances without the aid of calculators or pencil and paper. A simple model of backgammon is used to approximate those chances, and a readily computable and sufficiently accurate approximation of that is developed. From there, the model is compared to simulated backgammon games, and the previous approximation is modified to fit the real data
Length of Life of Vines of Various Species and Varieties of Grapes; Profitableness; and By What Diseases Seriously Affected.
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On the brink of change: plant responses to climate on the Colorado Plateau
The intensification of aridity due to anthropogenic climate change in the southwestern U.S. is likely to have a large impact on the growth and survival of plant species that may already be vulnerable to water stress. To make accurate predictions of plant responses to climate change, it is essential to determine the long-term dynamics of plant species associated with past climate conditions. Here we show how the plant species and functional types across a wide range of environmental conditions in Colorado Plateau national parks have changed with climate variability over the last twenty years. During this time, regional mean annual temperature increased by 0.188C per year from 1989–1995, 0.068C per year from 1995–2003, declined by 0.148C from 2003–2008, and there was high interannual variability in precipitation. Non-metric multidimensional scaling of plant species at long-term monitoring sites indicated five distinct plant communities. In many of the communities, canopy cover of perennial plants was sensitive to mean annual temperature occurring in the previous year, whereas canopy cover of annual plants responded to cool season precipitation. In the perennial grasslands, there was an overall decline of C3 perennial grasses, no change of C4 perennial grasses, and an increase of shrubs with increasing temperature. In the shrublands, shrubs generally showed no change or slightly increased with increasing temperature. However, certain shrub species declined where soil and physical characteristics of a site limited water availability. In the higher elevation woodlands, Juniperus osteosperma and shrub canopy cover increased with increasing temperature, while Pinus edulis at the highest elevation sites was unresponsive to interannual temperature variability. These results from well-protected national parks highlight the importance of temperature to plant responses in a water-limited region and suggest that projected increases in aridity are likely to promote grass loss and shrub expansion on the Colorado Plateau
Preliminary Solar Sail Design and Fabrication Assessment: Spinning Sail Blade, Square Sail Sheet
Blade design aspects most affecting producibility and means of measurement and control of length, scallop, fullness and straightness requirements and tolerances were extensively considered. Alternate designs of the panel seams and edge reinforcing members are believed to offer advantages of seam integrity, producibility, reliability, cost and weight. Approaches to and requirements for highly specialized metalizing methods, processes and equipment were studied and identified. Alternate methods of sail blade fabrication and related special machinery, tooling, fixtures and trade offs were examined. A preferred and recommended approach is also described. Quality control plans, inspection procedures, flow charts and special test equipment associated with the preferred manufacturing method were analyzed and are discussed
New Air-Launched Small Missile (ALSM) Flight Testbed for Hypersonic Systems
A new testbed for hypersonic flight research is proposed. Known as the Phoenix air-launched small missile (ALSM) flight testbed, it was conceived to help address the lack of quick-turnaround and cost-effective hypersonic flight research capabilities. The Phoenix ALSM testbed results from utilization of two unique and very capable flight assets: the United States Navy Phoenix AIM-54 long-range, guided air-to-air missile and the NASA Dryden F-15B testbed airplane. The U.S. Navy retirement of the Phoenix AIM-54 missiles from fleet operation has presented an excellent opportunity for converting this valuable flight asset into a new flight testbed. This cost-effective new platform will fill an existing gap in the test and evaluation of current and future hypersonic systems for flight Mach numbers ranging from 3 to 5. Preliminary studies indicate that the Phoenix missile is a highly capable platform. When launched from a high-performance airplane, the guided Phoenix missile can boost research payloads to low hypersonic Mach numbers, enabling flight research in the supersonic-to-hypersonic transitional flight envelope. Experience gained from developing and operating the Phoenix ALSM testbed will be valuable for the development and operation of future higher-performance ALSM flight testbeds as well as responsive microsatellite small-payload air-launched space boosters
Hamster and Murine Models of Severe Destructive Lyme Arthritis
Arthritis is a frequent complication of infection in humans with Borrelia burgdorferi. Weeks to months following the onset of Lyme borreliosis, a histopathological reaction characteristic of synovitis including bone, joint, muscle, or tendon pain may occur. A subpopulation of patients may progress to a chronic, debilitating arthritis months to years after infection which has been classified as severe destructive Lyme arthritis. This arthritis involves focal bone erosion and destruction of articular cartilage. Hamsters and mice are animal models that have been utilized to study articular manifestations of Lyme borreliosis. Infection of immunocompetent LSH hamsters or C3H mice results in a transient synovitis. However, severe destructive Lyme arthritis can be induced by infecting irradiated hamsters or mice and immunocompetent Borrelia-vaccinated hamsters, mice, and interferon-gamma- (IFN-γ-) deficient mice with viable B. burgdorferi. The hamster model of severe destructive Lyme arthritis facilitates easy assessment of Lyme borreliosis vaccine preparations for deleterious effects while murine models of severe destructive Lyme arthritis allow for investigation of mechanisms of immunopathology
Resource theory of quantum uncomplexity
Quantum complexity is emerging as a key property of many-body systems, including black holes, topological materials, and early quantum computers. A state's complexity quantifies the number of computational gates required to prepare the state from a simple tensor product. The greater a state's distance from maximal complexity, or “uncomplexity,” the more useful the state is as input to a quantum computation. Separately, resource theories—simple models for agents subject to constraints—are burgeoning in quantum information theory. We unite the two domains, confirming Brown and Susskind's conjecture that a resource theory of uncomplexity can be defined. The allowed operations, fuzzy operations, are slightly random implementations of two-qubit gates chosen by an agent. We formalize two operational tasks, uncomplexity extraction and expenditure. Their optimal efficiencies depend on an entropy that we engineer to reflect complexity. We also present two monotones, uncomplexity measures that decline monotonically under fuzzy operations, in certain regimes. This work unleashes on many-body complexity the resource-theory toolkit from quantum information theory
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