Evolutionary Algorithms, Markov Decision Processes, Adaptive Critic Designs, and Clustering: Commonalities, Hybridization and Performance

We briefly review and compare the mathematical formulation of Markov decision processes (MDP) and evolutionary algorithms (EA). In so doing, we observe that the adaptive critic design (ACD) approach to MDP can be viewed as a special form of EA. This leads us to pose pertinent questions about possible expansions of the methodology of ACD. This expansive view of EA is not limited to ACD. We discuss how it is possible to consider the powerful chained Lin Kernighan (chained LK) algorithm for the traveling salesman problem (TSP) as a degenerate case of EA. Finally, we review some recent TSP results, using clustering to divide-and-conquer, that provide superior speed and scalability

Characterizing stoichiometry and kinetics of two thermophilic nitrification communities : a crucial step in the development of thermophilic biotechnology for nitrogen removal

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A systematic literature review of the major factors causing yield gap by affecting growth, feed conversion ratio and survival in Nile tilapia (Oreochromis niloticus)

Abstract Productivity among small- and medium-scale tilapia farms varies considerably. The difference between the best performers and lower ones (yield gap), is affected by differences in growth rate and feed conversion ratio (FCR). FCR at the farm level is strongly influenced by survival of fish. In this study a systematic literature review of two databases (ASFA and CAB-Abstracts) identified 1973 potentially relevant articles. Data from 32 articles that met the inclusion criteria were analysed using linear mixed models for the most important factors with significant contributions to growth [investigated through analysis of the thermal growth coefficient (TGC)], survival and FCR of Nile tilapia. Increasing crude protein (CP), dissolved oxygen (DO) and pH significantly decreased FCR and increased TGC. Increasing stocking weight (SW) significantly improved both FCR and survival. Temperature had the largest effect on FCR followed by DO, pH and CP. DO had the largest effect on TGC followed by CP and pH. This study confirms that the optimal rearing temperature for Nile tilapia is between 27 and 32°C. Improving management to optimize DO (> 5 mg/L), stocking density (3–5 fish/m2), SW (> 10 g) and CP (25 − 30%) will improve performance and survival in small- and medium-scale tilapia farming. However, it is hard to influence temperature in ponds and cages while DO is largely influenced by aeration. Since many small- and medium-sized farms do not have aeration, these major tilapia farming systems could benefit from genetically improved strains selected for resilience to highly fluctuating diurnal temperature and DO levels

Variability in intermediate water circulation of the western Tyrrhenian margin (NE Corsica) over the past 56 kyr

The Marion Dufrene core MD01-2472 made of hemipelagic fine-grained sediments (silt and clays) was collected at 501 m depth on the East Corsica continental slope in 2001 and studied in detail in its 12 uppermost meters. The correlation between sedimentological parameters (Sortable Silt), isotopic data and 14C dating allowed to establish the chronology of main climate events (Younger Dryas/YD, Bölling-Alleröd/B-A, Heinrich events/HS) on this record and to evaluate the impact of major climate oscillations on bottom water condition variability. The sea temperature changes are identified thanks to the planktonic foraminifera assemblages. HS are marked by planktonic foraminifers with peaks of the polar species N. pachyderma (left-coiling), whilst interstadials are marked by warm planktonics that become very abundant during the B-A and Holocene. The occurrence of reworked ostracod species (originating from the continental shelf) and the presence of shallow water Elphidium/Ammonia benthic foraminifera are used to estimate the degree of along-slope transport at the core site. This has revealed two intervals of along-slope transport also associated with coarse-grained contourites, deposited during the YD and HS2 episodes. Intervals with Krithe spp. (ostracod), C. wuellerstorfi (benthic foraminifera) indicate bottom water oxygenation during stadials, whereas interstadials are typified by A. acuminata and Paracypris sp (ostracods) indicating low oxygenated environments. The Last Glacial Maximum is dominated by the planktonic foraminifer T. quinqueloba suggesting high surface primary productivity associated with the establishment of mestrophic bottom conditions. During the Holocene, benthic assemblages indicate oligo-mesotrophic conditions and weak hydrodynamic bottom regime. We hypothesize that there is relationship between the Levantine Intermediate Water (LIW) intensification during cold rapid climate events and benthic fauna assemblages due to changes in: 1) bottom water ventilation, corresponding to a significant reinforcement of the LIW velocity, and 2) the export of nutrients (generating changes in trophic conditions) and/or sediment particles by bottom currents (contributing to the formation of contourites)

13C Incorporation as a tool to estimate biomass yields in thermophilic and mesophilic nitrifying communities

Current methods determining biomass yield require sophisticated sensors for in situ measurements or multiple steady-state reactor runs. Determining the yield of specific groups of organisms in mixed cultures in a fast and easy manner remains challenging. This study describes a fast method to estimate the maximum biomass yield (Y-max ), based on C-13 incorporation during activity measurements. It was applied to mixed cultures containing ammonia oxidizing bacteria (AOB) or archaea (AOA) and nitrite oxidizing bacteria (NOB), grown under mesophilic (15-28 degrees C) and thermophilic (50 degrees C) conditions. Using this method, no distinction could be made between AOB and AOA co-existing in a community. A slight overestimation of the nitrifier biomass due to C-13 redirection via SMP to heterotrophs could occur, meaning that this method determines the carbon fixation activity of the autotrophic microorganisms rather than the actual nitrifier biomass yield. Thermophilic AOA yields exceeded mesophilic AOB yields (0.22 vs. 0.06-0.11 g VSS g(-1) N), possibly linked to a more efficient pathway for CO(2 )incorporation. NOB thermophilically produced less biomass (0.025-0.028 vs. 0.048-0.051 g VSS g(-1) N), conceivably attributed to higher maintenance requirement, rendering less energy available for biomass synthesis. Interestingly, thermophilic nitrification yield was higher than its mesophilic counterpart, due to the dominance of AOA over AOB at higher temperatures. An instant temperature increase impacted the mesophilic AOB yield, corroborating the effect of maintenance requirement on production capacity. Model simulations of two realistic nitrification/denitrification plants were robust toward changing nitrifier yield in predicting effluent ammonium concentrations, whereas sludge composition was impacted. Summarized, a fast, precise and easily executable method was developed determining Y(max )of ammonia and nitrite oxidizers in mixed communities

Characterization of Fat Fraction Kinetics Using Dixon Magnetic Resonance Imaging in Association With Radiation-Related Lymphedema

https://openworks.mdanderson.org/radonc24/1002/thumbnail.jp

Evaluation of the Dixon-Derived Fat Fraction Changes in Lymphatic Tissues Following Radiotherapy

https://openworks.mdanderson.org/radonc24/1005/thumbnail.jp

Fluctuations in growth are heritable and a potential indicator of resilience in Nile tilapia (Oreochromis niloticus)

Resilience can be defined as the capacity of an animal to be minimally affected by perturbations or to quickly recover to the state it had before the perturbation. When applied to production animals, resilience is defined as consistency in production over time. This consistency can be quantified by the variance of deviations from the expected trait level measured at multiple time points. The objectives of this study were to estimate genetic parameters for resilience in Nile tilapia, measured as consistency in growth. We used log-transformed variance of deviations (LnVar) of body weight measured five times during grow-out in either an aerated or a non-aerated pond. The hypothesis was that fish grown in non-aerated ponds are more challenged by environmental conditions, such that heritable variation in LnVar of body weight is more expressed showing larger differences between more and less resilient fish. The heritability for LnVar was 0.10 in aerated pond and 0.12 in the non-aerated pond. In aerated ponds the genetic correlation (rg) of LnVar with harvest weight (HW) was 0.36 ± 0.26, and with thermal growth coefficient (TGC) it was 0.47 ± 0.21. In the non-aerated pond, the rg with HW and TGC were close to zero (−0.01 ± 0.29 and − 0.08 ± 0.22). The genetic correlation for LnVar between both environments was 0.80. These estimates suggest that selection for HW or TGC in aerated ponds will increase LnVar in both environments. Increased LnVar may decrease resilience and this will be detrimental to performance. Selecting for more resilient fish would lead to more constant growth rates, which makes biomass estimation more accurate and could therefore result in more optimal feeding regimes and less feed waste. This would have a favorable effect on the feed efficiency in production units and on the environmental impact of fish farming. To improve resilience together with growth we recommend that fish breeding programs collect repeated records on body weight, preferably in challenging environments

Prospective Evaluation of In Vivo and Phantom Repeatability and Reproducibility of Diffusion-Weighted MRI Sequences on 1.5 T MRI-Linear Accelerator (MR-Linac) and MR Simulator Devices for Head and Neck Cancers

INTRODUCTION: Diffusion-weighted imaging (DWI) on MRI-linear accelerator (MR-linac) systems can potentially be used for monitoring treatment response and adaptive radiotherapy in head and neck cancers (HNC) but requires extensive validation. We performed technical validation to compare six total DWI sequences on an MR-linac and MR simulator (MR sim) in patients, volunteers, and phantoms. METHODS: Ten human papillomavirus-positive oropharyngeal cancer patients and ten healthy volunteers underwent DWI on a 1.5 T MR-linac with three DWI sequences: echo planar imaging (EPI), split acquisition of fast spin echo signals (SPLICE), and turbo spin echo (TSE). Volunteers were also imaged on a 1.5 T MR sim with three sequences: EPI, BLADE (vendor tradename), and readout segmentation of long variable echo trains (RESOLVE). Participants underwent two scan sessions per device and two repeats of each sequence per session. Repeatability and reproducibility within-subject coefficient of variation (wCV) of mean ADC were calculated for tumors and lymph nodes (patients) and parotid glands (volunteers). ADC bias, repeatability/reproducibility metrics, SNR, and geometric distortion were quantified using a phantom. RESULTS: In vivo repeatability/reproducibility wCV for parotids were 5.41%/6.72%, 3.83%/8.80%, 5.66%/10.03%, 3.44%/5.70%, 5.04%/5.66%, 4.23%/7.36% for EPI CONCLUSION: MR-linac DWI sequences demonstrated near-comparable performance to MR sim sequences and warrant further clinical validation for treatment response assessment in HNC

'Tough'-constructions and their derivation

This article addresses the syntax of the notorious 'tough' (-movement) construction (TC) in English. TCs exhibit a range of apparently contradictory empirical properties suggesting that their derivation involves the application of both A-movement and A'-movement operations. Given that within previous Principles and Parameters models TCs have remained “unexplained and in principle unexplainable” (Holmberg 2000: 839) due to incompatibility with constraints on theta-assignment, locality, and Case, this article argues that the phase-based implementation of the Minimalist program (Chomsky 2000, 2001, 2004) permits a reanalysis of null wh-operators capable of circumventing the previous theoretical difficulties. Essentially, 'tough'-movement consists of A-moving a constituent out of a “complex” null operator which has already undergone A'-movement, a “smuggling” construction in the terms of Collins (2005a,b