1st BUKHARA INTERNATIONAL MEDICAL STUDENTS CONFERENCE

  1st BUKHARA INTERNATIONAL MEDICAL STUDENTS CONFERENC

Occluded renal artery and a contralateral moderate renal artery stenosis – Which side should be treated?

Renal artery stenosis is the most common secondary cause of hypertension. We present a case of a 22-year-old man with uncontrolled hypertension despite taking four antihypertensive medications including a diuretic agent. Duplex ultrasound showed bilateral renal artery stenosis with total occlusions of the right renal artery and moderate stenosis (60%) of left renal artery. Renogram showed decreased function of both kidneys especially in the right. Renal fractional flow reserve showed no significant hemodynamic disturbance in the left renal artery. Thus, percutaneous transluminal angioplasty with renal stenting was performed in the right renal artery. After one month of follow up, the patient showed no symptoms, good control of blood pressure and improvement of kidney function. Renal scintigraphy and renal fractional flow reserve measurement play an important role for clinical decision making regarding the need for renal revascularization

Probiotics in the Management of Atopic Dermatitis for Children: A Case-Based Review

Background. Atopic dermatitis or eczema is one of the most common dermatologic problems, especially in children. Several studies have hypothesized that alteration of gut-colonizing microbes might have induced and conditioned the development of the disease. Thus, modulation of microbial diversity and abundance might help alleviate symptoms and conditions for patients. Given the ability of commensal and symbiotic microorganisms in modulating the immune system, probiotics administration has been studied in previous research in the management of eczema. However, until today, there are conflicting results between studies making inconclusive recommendations towards probiotics supplementation in the management of atopic dermatitis. This case-based review was done to assess and evaluate the therapeutic efficacy of probiotics supplementation in the management of eczema in children. Method. An electronic database search was conducted in PubMed-NCBI, Cochrane, EBSCO, ProQuest, and SCOPUS in March 2020. Individual studies and reviews were then gathered for screening using predetermined inclusion and exclusion criteria. The included studies were then critically appraised for their validity and importance. Result. A total of 5 studies, all of which were RCTs, were included in this review. Out of all the studies included, 4 showed no clinically significant improvements in using probiotics in the management of eczema in children as they did not pass the minimal clinically important difference (MCID) of eczema severity as determined by SCORAD (SCORing Atopic Dermatitis). Conclusion. Supplementation of probiotics in the management of eczema in children does not show a clinically relevant difference vs. standard treatment in reducing eczema severity