Medidas cautelares en los procesos de violencia de género

En el presente trabajo hablaremos en profundidad sobre el delito de violencia de género, con especial énfasis y análisis de la Ley Orgánica de 1/2004, de 28 de diciembre, de Medidas de Protección Integral contra la Violencia de Género. Además, veremos en profundidad la Orden de protección contenida en el art. 544 ter de la Ley de Enjuiciamiento Criminal en contraste con las medidas cautelares reguladas en el art. 544 bis del mismo cuerpo legal, que, a priori, pueden parecer conceptos similares, pero, sin embargo, no lo son. También los presupuestos para acordar la orden de protección, así como el contenido y procedimiento del mismo. Y, por último, las diferentes medidas de protección que contiene el estatuto de protección integral de la víctima que otorga la condición de víctima para la mujer habilitándose medidas de naturaleza civil, penal y/o asistencia social.In this paper we will talk in depth about the gender violence crime, with special emphasis and analysis of the Organic Law of 1/2004, of December 28, on Comprehensive Protection Measures against Gender Violence. In addition, we will see in detail the Protection Order contained in art. 544 ter of the Criminal Procedure Law in contrast to the precautionary measures regulated in art. 544 bis of the same legal body, which, a priori, may seem similar in concept, however, they are not. Within this study, we will revise the budgets to arrange for the protection order, as well as the content and procedure thereof. And, finally, the different protection measures contained in the comprehensive victim protection statute that grants the status of victim to women, enabling measures of a civil, criminal and / or social assistance nature.Máster Universitario en Acceso a la Profesión de Abogado (M155

Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid

We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. One of the patients had reactions to several unrelated drugs. Increased awareness of anaphylaxis to excipients such as macrogols is needed, especially when allergy tests for the active drug is negative and in patients with a history of repeated anaphylaxis to seemingly unrelated drugs. To establish the correct diagnosis it is important to test with the exact formulation of the culprit drug, as well as all the ingredients including excipients

Extensive gene rearrangements in the mitogenomes of congeneric annelid species and insights on the evolutionary history of the genus Ophryotrocha

Background Annelids are one the most speciose and ecologically diverse groups of metazoans. Although a significant effort has been recently invested in sequencing genomes of a wide array of metazoans, many orders and families within the phylum Annelida are still represented by a single specimen of a single species. The genus of interstitial annelids Ophryotrocha (Dorvilleidae, Errantia, Annelida) is among these neglected groups, despite its extensive use as model organism in numerous studies on the evolution of life history, physiological and ecological traits. To compensate for the paucity of genomic information in this genus, we here obtained novel complete mitochondrial genomes of six Ophryotrocha species using next generation sequencing. In addition, we investigated the evolution of the reproductive mode in the Ophryotrocha genus using a phylogeny based on two mitochondrial markers (COXI and 16S rDNA) and one nuclear fragment (Histone H3). Results Surprisingly, gene order was not conserved among the six Ophryotrocha species investigated, and varied greatly as compared to those found in other annelid species within the class Errantia. The mitogenome phylogeny for the six Ophryotrocha species displayed a separation of gonochoric and hermaphroditic species. However, this separation was not observed in the phylogeny based on the COX1, 16S rDNA, and H3 genes. Parsimony and Bayesian ancestral trait reconstruction indicated that gonochorism was the most parsimonious ancestral reproductive mode in Ophryotrocha spp. Conclusions Our results highlight the remarkably high level of gene order variation among congeneric species, even in annelids. This encourages the need for additional mitogenome sequencing of annelid taxa in order to properly understand its mtDNA evolution, high biodiversity and phylogenetic relationships. -- Keywords : Molecular phylogeny ; Dorvilleidae ; Mitogenome ; Next generation sequencing ; Model species ; Reproductive mode

Severe and ChRonic Atopic dermatitis Treatment CoHort (SCRATCH):A Danish Real-world Evidence Atopic Dermatitis Treatment Registry

Data from real-world use of new systemic treatments in atopic dermatitis (AD) is important for assessing safety and efficacy. The aim of this study is to describe the baseline characteristics of adult patients with moderate-to-severe AD enrolled in the Danish nationwide Severe and ChRonic Atopic dermatitis Treatment CoHort (SCRATCH) database, between October 2017 and August 2021. A total of 282 adult patients were included. Most (62%) were men, the median age at baseline was 43 years (interquartile range (IQR) 29–54 years), and median age at onset of AD was 1 year (IQR 0–6 years). The median Eczema Area and Severity Index at treatment initiation was 19.1 (IQR 11.9–25.7); median Patient Oriented Eczema Measure 21.0 (IQR 16.0–25.0); median Dermatology Life Quality Index 13.0 (IQR 7.0–19.0); and median itch and sleep numerical rating scale scores 8.0 (IQR 6.0–9.0) and 6.0 (IQR 4.0–8.0). Differences were found between the sexes. This registry will provide a source for future efficacy and safety studies

An observer‐blinded randomized controlled pilot trial comparing localized immersion psoralen–ultraviolet A with localized narrowband ultraviolet B for the treatment of palmar hand eczema

Background: Hand eczema is a common inflammatory dermatosis that causes significant patient morbidity. Previous studies comparing psoralen–ultraviolet A (PUVA) with narrowband ultraviolet B (NB‐UVB) have been small, nonrandomized and retrospective. Objectives: To conduct an observer‐blinded randomized controlled pilot study using validated scoring criteria to compare immersion PUVA with NB‐UVB for the treatment of chronic hand eczema unresponsive to topical steroids. Methods: Sixty patients with hand eczema unresponsive to clobetasol propionate 0·05% were randomized to receive either immersion PUVA or NB‐UVB twice weekly for 12 weeks with assessments at intervals of 4 weeks. The primary outcome measure was the proportion of patients achieving ‘clear’ or ‘almost clear’ Physician's Global Assessment (PGA) response at 12 weeks. Secondary outcome measures included assessment of the modified Total Lesion and Symptom Score (mTLSS) and the Dermatology Life Quality index (DLQI). Results: In both treatment arms, 23 patients completed the 12‐week assessment for the primary outcome measure. In the PUVA group, five patients achieved ‘clear’ and eight ‘almost clear’ [intention‐to‐treat (ITT) response rate 43%]. In the NB‐UVB group, two achieved ‘clear’ and five ‘almost clear’ (ITT response rate 23%). For the secondary outcomes, median mTLSS scores were similar between groups at baseline (PUVA 9·5, NB‐UVB 9) and at 12 weeks (PUVA 3, NB‐UVB 4). Changes in DLQI were similar, with improvements in both groups. Conclusions: In this randomized pilot trial recruitment was challenging. After randomization, there were acceptable levels of compliance and safety in each treatment schedule, but lower levels of retention. Using validated scoring systems – PGA, mTLSS and DLQI – as measures of treatment response, the trial demonstrated that both PUVA and NB‐UVB reduced the severity of chronic palmar hand eczema

The need for improved transition and services for adolescent and young adult patients with allergy and asthma in all settings

Adolescence is a challenging time for both patients and healthcare providers. Adolescent patients need to learn all the knowledge and skills required to competently and confidently self-manage their allergy and asthma. They have to negotiate the challenging transition from being children, whose medical care is supervised by their parents, to independent expert adult patients. Although adolescent and young adult patients appear to be very robust, the reality is that they have often had a poor experience of medical care and are at surprisingly high risk of morbidity and mortality.</p