El tabernáculo de Guillermo de Orta para la capilla del Sagrario de la catedral de Córdoba

El trabajo se centra en el análisis del tabernáculo del Sagrario de la catedral de Córdoba como imagen del Santo Sepulcro de Jerusalén, en el contexto de la capilla del Sagrario que se concibe como Casa de la Sabiduría y del conjunto catedralicio que se presenta como la Nueva Jerusalén de Córdoba en el siglo XVI, centuria en la que se convierte en uno de los puntos neurálgicos del ceremonial litúrgico celebrado en el espacio sacralizado de la antigua aljama de Córdoba, identificándose la ciudad celeste con la ciudad real.This work focuses on the tabernacle in the Sanctuary of Cordoba Cathedral as an image of the Holy Sepulchre of Jerusalem, in the context of the Sanctuary Chapel. This was designed as a House of Wisdom inside the Cathedral, which in the sixteenth century was thought of as the ‘New Jerusalem of Cordoba’. In this century, it became one of the key venues for the liturgical ceremonies held in the sanctified area of the old Mosque of Cordoba, and this celestial city was identified closely with the real city

Synthesis of Multibranched Australine Derivatives from Reducing Castanospermine Analogues through the Amadori Rearrangement of gem

© 2014 American Chemical Society. A practical one-pot synthesis of bi- and triantennated australine analogues from a pivotal sp2-iminosugar-type reducing castanospermine precursor is reported. The transformation involves a gem-diamine intermediate that undergoes the indolizidine → pyrrolizidine Amadori-type rearrangement and proceeds under strict control of the generalized anomeric effect to afford a single diastereomer. The final compounds behave as selective competitive inhibitors of β-glucosidase and are promising candidates as pharmacological chaperones for Gaucher disease.Peer Reviewe

Fullerene–Ionic-Liquid Conjugates: A New Class of Hybrid Materials with Unprecedented Properties

A modular approach has been followed for the synthesis of a series of fullerene–ionic-liquid (IL) hybrids in which the number of IL moieties (two or twelve), anion, and cation have been varied. The combination of C60 and IL give rise to new unique properties in the conjugates such as solubility in water, which was higher than 800 mg mL−1 in several cases. In addition, one of the C60–IL hybrids has been employed for the immobilization of palladium nanoparticles through ion exchange followed by reduction with sodium borohydride. Surprisingly, during the reduction several carbon nanostructures were formed that comprised nano-onions and nanocages with few-layer graphene sidewalls, which have been characterized by means of thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), scanning electron microscopy/energy-dispersive X-ray analysis (SEM-EDAX), and high-resolution transmission electron microscopy (HRTEM). Finally, the material thus obtained was successfully applied as catalyst in Suzuki and Mizoroki–Heck reactions in a concentration of just 0.2 mol %. In the former process it was recyclable for five runs with no loss in activity