Computerized conductometric determination of stability constants of complexes of crown ethers with alkali metal salts and with neutral molecules in polar solvents

A computerized conductometric procedure for the determination of stability constants of the complexes of crown ethers (15-crown-5, benzo-15-crown-5 and 12-crown-4) with alkali metal salts in polar solvents is described, based on a microcomputer-controlled titration system. For the control of the experiments from software, a modular computer program was written in FORTH computer language. The procedure is especially suitable for the study of 1:2 metal ion/ligand complexes, which occur frequently with the compounds used. For the study of the interaction between crown ethers and neutral molecules, an indirect procedure is outlined

Development of drug delivery systems based on layered hydroxides for nanomedicine

Layered hydroxides (LHs) have recently fascinated researchers due to their wide application in various fields. These inorganic nanoparticles, with excellent features as nanocarriers in drug delivery systems, have the potential to play an important role in healthcare. Owing to their outstanding ion-exchange capacity, many organic pharmaceutical drugs have been intercalated into the interlayer galleries of LHs and, consequently, novel nanodrugs or smart drugs may revolutionize in the treatment of diseases. Layered hydroxides, as green nanoreservoirs with sustained drug release and cell targeting properties hold great promise of improving health and prolonging life

Aquatic chemistry

International audienc

Binding of monovalent metal cations by the p-sulfonatocalix[4]arene: experimental evidence for cation-pi interactions in water.

International audienc

Partage de quelques cryptates alcalins et alcalino-terreux entre l'eau et l'octanol

Les constantes de partage entre l'eau et l'octanol-1 des cryptates du 222 avec le potassium, le calcium et le baryum associés à quelques anions minéraux et au p-nitrophénate ont été déterminées, ainsi que les mêmes constantes relatives aux ions tétrapropylammonium et tétrabuty- lammonium. Les caractères lipophiles de ces différents cations sont comparés