Olho seco causado por infecções virais: revisão

Dry eye disease and ocular surface disorders may be caused or worsened by viral agents. There are several known and suspected virus associated to ocular surface diseases. The possible pathogenic mechanisms for virus-related dry eye disease are presented herein. This review serves to reinforce the importance of ophthalmologists as one of the healthcare professional able to diagnose a potentially large number of infected patients with high prevalent viral agents.A síndrome do olho seco e as doenças de superfície ocular podem ser causadas ou agravadas por agentes virais. Diversos vírus são causadores ou tem associação suspeitada com as doenças de superfície ocular. Esta revisão apresenta os possíveis mecanismos patogênicos envolvidos no olho seco causado por infecões virais e reinforça a importância do oftalmologista como um dos profissionais de saúde capazes de diagnosticar um grande número de pacientes infectados por agentes virais altamente prevalentes.12913

Avaliação do uso do retro-alimentador em atendentes de telefone visando a prevenção das DORTs

Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.As patologias denominadas genericamente como Lesões por Esforços Repetitivos (LERs), apresentando sinais e sintomas de inflamações de tecidos moles dos membros superiores, cintura escapular e pescoço, principalmente, têm chamado a atenção pelo aumento de sua incidência e pelas evidências de sua associação com o ritmo de trabalho. A presente pesquisa, realizada entre os meses de novembro/01 a junho/02, do tipo exploratória, descritiva e avaliativa, teve como objetivo avaliar o uso do retro-alimentador em atendentes de telefone visando a prevenção das DORTs.(distúrbios osteomusculares relacionadas ao trabalho) nos trabalhadores da COPEL (Companhia de Energia Elétrica do Paraná). O estudo procurou avaliar se o biofeedback associado à correção postural realmente diminuiria as dores, fadiga e cansaço, já presentes em alguns funcionários, e qual realmente seria o tempo mínimo de uso do aparelho para se ter uma resposta significativa. A coleta de dados deu-se por meio de questionário elaborado pela Universidade Federal do Paraná e validado num estudo realizado no SERPRO (Serviço Federal de Processamento de Dados) em Curitiba - PR, além de técnicas de entrevista, análise documental, fotos, filmagens e observação. Num segundo momento os 24 trabalhadores foram devidamente analisados, a fim de classificá-los como portadores ou não de LER. Em conclusão, constatou-se que a utilização do biofeedback no treinamento inicia sua ação em média de trinta minutos e começa, então, a ter efeito significativo na diminuição da dor, fadiga e cansaço por adotarem uma postura correta

BRICS and Mediated Narratives: The Proximity Between Brazilian News and Telenovelas

By analyzing the telenovela Caminho das Indias, broadcasted in 2009 and then again in 2015, this article discusses the concept of BRICS, more specifically of Brazil and India, and the question of soft power as a possibility of communicative and cultural influence which could contribute, through the diversity that is a staple of the block, to propose a counterpoint to the contemporary monoculture of worldviews. The argument used here is that audiovisual transnational narratives such as films (India) and television (Brazil) establish an important bridge between journalism and fiction. This is because they exercise, to some extent, an 'agenda-setting' role, in other words they are transformed newsworthy media, presenting the public with events and reflections on current issues. This paper discusses the relationship between the mediation between information-entertainment specifically in Brazilian telenovelas, analyzing the representation of the two countries through Brazilian author Gloria Perez’s work

Representation of domestic violence in Brazilian serialized productions

The purpose of this article is to analyze the representation of domestic violence geared towards women in Brazilian serialized television narratives. It is a comparative analysis, with a critical/comprehensive perspective, borrowing from the narrative and imagined traditions. This work is a case study of the telenovela Mulheres Apaixonadas (Women in Love, Globo) and the series Sessão de Terapia (Therapy Session, Globosat News Television – GNT). Our purpose is to find out how these two narrative productions represent and present domestic violence to their respective audiences, taking into account aspects about production, public, open and paid TV.A proposta deste artigo é refletir a respeito da representação da violência doméstica em relação a mulheres em narrativas seriadas televisivas. Trata-se de uma análise comparativa, com uma perspectiva crítica/ compreensiva, no campo dos estudos das narrativas e do imaginário. Este trabalho tem como corpus a telenovela Mulheres Apaixonadas (Globo) e o seriado Sessão de Terapia (Globosat News Television – GNT). O intuito é analisar e contrastar como essas duas produções narrativas representam e apresentam a violência doméstica às suas respectivas audiências, levando-se em conta aspectos sobre produção, público, TV aberta e paga

Nanocrystalline Anatase Tio2/reduced Graphene Oxide Composite Films As Photoanodes For Photoelectrochemical Water Splitting Studies: The Role Of Reduced Graphene Oxide.

Nanocrystalline TiO2 and reduced graphene oxide (TiO2/RGO) composite films were prepared by combining a sol-gel method with hydrothermal treatment, employing titanium isopropoxide (Ti(O(i)Pr)4) and graphene oxide (GO) as starting materials. Although several reports in the literature have explored the benefits of RGO addition in titania films for photocatalysis and water splitting reactions, the role of RGO in the composite is always described as that of a material that is able to act as an electron acceptor and transport electrons more efficiently. However, in most of these reports, no clear evidence for this role is presented, and the main focus is deviated to the improved efficiency and not to the reasons for said efficiency. In this study, we employed several techniques to definitively present our understanding of the role of RGO in titania composite films. The TiO2/RGO composite films were characterized by X ray diffraction, Raman spectroscopy, microscopy and electrochemical techniques. In photoelectrochemical water splitting studies, the TiO2/RGO(0.1%) photoelectrodes showed the highest photocurrent density values (0.20 mA cm(-2) at 1.23 VRHE) compared to other electrodes, with an increase of 78% in relation to pristine TiO2 film (0.11 mA cm(-2) at 1.23 VRHE). The transient absorption spectroscopy (TAS) results indicated increases in the lifetime and yield of both the photogenerated holes and electrons. Interestingly, the TiO2/RGO(0.1%) film exhibited the best charge generation upon excitation, corroborating the photoelectrochemical data. We proposed that in films with lower concentrations (<0.1 wt%), the RGO sheets are electron acceptors, and a decrease in the charge recombination processes is the immediate consequence. Thus, both holes and electrons live longer and contribute more effectively to the photocurrent density.182608-261

Boro afeta o crescimento e a ultra-estrutura da mamoneira

A mamoneira é uma oleaginosa com grande potencial para a geração de renda na agricultura familiar e para produção de matéria prima para a indústria química e setor energético brasileiro, especialmente em regiões do semi-árido nordestino. A deficiência de boro (B) ocorre de forma generalizada no Brasil e a aplicação excessiva deste micronutriente pode causar toxicidade. Este estudo avalia o desenvolvimento e os efeitos ultra-estruturais de deficiência e toxicidade de boro em mamoneira. O experimento foi realizado em condições de casa de vegetação, com vasos de 10 L de solução nutritiva. Foram utilizados três tratamentos: testemunha (sem B); 0,27 e 5,40 mg L-1 B, uma planta por vaso, em delineamento experimental inteiramente ao acaso com três repetições. A produção de matéria seca de cada parte da planta foi avaliada e o teor de boro determinado. Foram observados os efeitos morfológicos e as alterações na ultra-estrutura celular nas folhas e pecíolos, através da técnica de microscopia eletrônica de transmissão e varredura. A produção de matéria seca da mamoneira foi afetada em condições de deficiência de boro, mas não em condições de toxicidade (5,4 mg L-1 B). Neste último tratamento foram constatadas cloroses nos bordos de folhas velhas e ausência de grânulos de amido. Na omissão de boro, as plantas apresentaram deformação de folhas novas, morte do meristema apical, engrossamento da lamela média, ausência de grânulos de amido nos cloroplastos e desorganização dos vasos condutores do pecíolo. O desenvolvimento e a produção da mamoneira são afetados em condições de deficiência de boro mas não na condição de toxicidade.The cultivation of oleaginous plants like the castor bean guarantees employment for agricultural families and can contribute in energy and chemical sectors, especially in the northeastern semi-arid regions of Brazil. Boron (B) deficiency is a widespread nutritional disorder despite the fact that various anthropogenic sources with high B content may increase soil B to toxic levels for plants. The present study was designed to investigate the ultrastructural effects of boron deficiency and toxicity on castor bean plants which were grown under greenhouse condition using plastic containers with 10 L of nutrient solution. Boron treatments comprised: control (no B); 0.27 mg L-1, 5.40 mg L-1 B pots (one plant per pot), tested in a completely randomized design with three replicates. The dry matter of all plant parts and B concentration were determined. Cellular ultrastructure was evaluated by transmission and scanning electron microscopy on samples of leaves and petioles. Dry matter yield was affected by the B absence treatment but there was no difference for the 5.4 mg L-1 B (toxic conditions) treatment. A marginal leaf burn at edge and tips of oldest leaves and absence of starch granules in chloroplasts were noted for the B toxicity treatment. The deformation of the youngest leaves, the death of the apical meristem as well as the swelling of the middle lamella, absence of starch granules in chloroplasts and petiole vessels untidily were observed in the B absent treatment. It is concluded that the production and development of castor bean plants is affected by boron deficiency, but not for boron toxicity conditions

Interrelationship between implant and orthognathic surgery for the rehabilitation of edentulous cleft palate patients: a case report

A 43-year-old woman with a unilateral cleft lip and palate, presenting a totally edentulous maxilla and mandible with marked maxillomandibular discrepancy, attended the Prosthodontics section of the Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo for treatment. She could not close her mouth and was dissatisfied with her complete dentures. Treatment planning comprised placement of six implants in the maxilla, four in the mandible followed by prostheses installation and orthognathic surgery. The mandibular full arch prosthesis guided the occlusion for orthognathic positioning of the maxilla. The maxillary complete prosthesis was designed to assist the orthognathic surgery with a provisional prosthesis (no metal framework), allowing reverse treatment planning. Maxillary and mandibular realignment was performed. Three months later, a relapse in the position of the maxilla was observed, which was offset with a new maxillary prosthesis. This isa complex interdisciplinary treatment and two-year follow-up is presented and discussed. It should be considered that this type of treatment could also be applied in non-cleft patients

Changes in cardiac heparan sulfate proteoglycan expression and streptozotocin-induced diastolic dysfunction in rats

<p>Abstract</p> <p>Background</p> <p>Changes in the proteoglycans glypican and syndecan-4 have been reported in several pathological conditions, but little is known about their expression in the heart during diabetes. The aim of this study was to investigate in vivo heart function changes and alterations in mRNA expression and protein levels of glypican-1 and syndecan-4 in cardiac and skeletal muscles during streptozotocin (STZ)-induced diabetes.</p> <p>Methods</p> <p>Diabetes was induced in male Wistar rats by STZ administration. The rats were assigned to one of the following groups: control (sham injection), after 24 hours, 10 days, or 30 days of STZ administration. Echocardiography was performed in the control and STZ 10-day groups. Western and Northern blots were used to quantify protein and mRNA levels in all groups. Immunohistochemistry was performed in the control and 30-day groups to correlate the observed mRNA changes to the protein expression.</p> <p>Results</p> <p>In vivo cardiac functional analysis performed using echocardiography in the 10-day group showed diastolic dysfunction with alterations in the peak velocity of early (E) diastolic filling and isovolumic relaxation time (IVRT) indices. These functional alterations observed in the STZ 10-day group correlated with the concomitant increase in syndecan-4 and glypican-1 protein expression. Cardiac glypican-1 mRNA and skeletal syndecan-4 mRNA and protein levels increased in the STZ 30-day group. On the other hand, the amount of glypican in skeletal muscle was lower than that in the control group. The same results were obtained from immunohistochemistry analysis.</p> <p>Conclusion</p> <p>Our data suggest that membrane proteoglycans participate in the sequence of events triggered by diabetes and inflicted on cardiac and skeletal muscles.</p