Repositórios para tecnologias sociais de área rural em Brasília

The objective of this study is to demonstrate the indication of a project of application of the techniques and tools of the area of Information Science in the support to the dissemination and use of the information of Social Technologies developed in the field of nucleus of the North Lake, Brasilia, Distrito Federal. Thus, the indicated methodology is an applied research with the use of field research with a qualitative and quantitative approach. As a result, a site of the proposing institution with DSpace and AtoM. We can conclude that the use of the repositories will make available and provide access to the available information on Social Technologies developed by the community of inhabitants of the rural nucleus of Serrinha do Paranoá, enabling replication and learning by expanding the sustainability of the region.El objetivo de este estudio es demostrar la indicación de un proyecto de aplicación de las técnicas y herramientas del área de Ciencia de la Información en el apoyo a la difusión y uso de la información de Tecnologías Sociales desarrollada en el campo del núcleo del Lago Norte, Brasilia, Distrito Federal. Por lo tanto, la metodología indicada es una investigación aplicada con el uso de la investigación de campo con un enfoque cualitativo y cuantitativo. Como resultado, un sitio de la institución proponente con DSpace y AtoM. Podemos concluir que el uso de los repositorios pondrá a disposición y proporcionará acceso a la información disponible sobre Tecnologías Sociales desarrollada por la comunidad de habitantes del núcleo rural de Serrinha do Paranoá, permitiendo la replicación y el aprendizaje mediante la expansión de la sostenibilidad de la región.O objetivo deste estudo é o demonstrar a indicação de um projeto de aplicação das técnicas e ferramentas da área da Ciência da Informação no apoio a disseminação e utilização da informação de Tecnologias Sociais desenvolvidas no âmbito dos núcleos rurais do Lago Norte, Brasília, Distrito Federal. Assim, a metodologia indicada é uma pesquisa aplicada com utilização de pesquisa de campo com abordagem qualitativa e quantitativa. Como resultados um site da instituição proponente com DSpace e AtoM. Podemos concluir que a utilização dos repositórios disponibilizará e propiciará o acesso as informações sobre as Tecnologias Sociais desenvolvidas pela comunidade de moradores dos núcleos rurais da Serrinha do Paranoá, possibilitando a replicação e a aprendizagem ampliando a sustentabilidade da região

Mantle dynamics of the Andean Subduction Zone from continent-scale teleseismic S-wave tomography

The Andean Subduction Zone is one of the longest continuous subduction zones on Earth. The relative simplicity of the two-plate system has makes it an ideal natural laboratory to study the dynamics in subduction zones. We measure teleseismic S and SKS traveltime residuals at >1000 seismic stations that have been deployed across South America over the last 30 yr to produce a finite-frequency teleseismic S-wave tomography model of the mantle beneath the Andean Subduction Zone related to the Nazca Plate, spanning from ~5°N to 45°S and from depths of ~130 to 1200 km. Within our model, the subducted Nazca slab is imaged as a fast velocity seismic anomaly. The geometry and amplitude of the Nazca slab anomaly varies along the margin while the slab anomaly continues into the lower mantle along the entirety of the subduction margin. Beneath northern Brazil, the Nazca slab appears to stagnate at ~1000 km depth and extend eastward subhorizontally for >2000 km. South of 25°S the slab anomaly in the lower mantle extends offshore of eastern Argentina, hence we do not image if a similar stagnation occurs. We image several distinct features surrounding the slab including two vertically oriented slow seismic velocity anomalies: one beneath the Peruvian flat slab and the other beneath the Paraná Basin of Brazil. The presence of the latter anomaly directly adjacent to the stagnant Nazca slab suggests that the plume, known as the Paraná Plume, may be a focused upwelling formed in response to slab stagnation in the lower mantle. Additionally, we image a high amplitude fast seismic velocity anomaly beneath the Chile trench at the latitude of the Sierras Pampeanas which extends from ~400 to ~1000 km depth. This anomaly may be the remnants of an older, detached slab, however its relationship with the Nazca-South America subduction zone remains enigmatic.Fil: Rodríguez, Emily E.. University of Arizona; Estados UnidosFil: Portner, Daniel Evan. No especifíca;Fil: Beck, Susan L.. University of Arizona; Estados UnidosFil: Rocha, Marcelo P.. Universidade do Brasília; BrasilFil: Bianchi, Marcelo B.. Universidade de Sao Paulo; BrasilFil: Assumpção, Marcelo. Universidade de Sao Paulo; BrasilFil: Ruiz, Mario. Escuela Politécnica Nacional; EcuadorFil: Alvarado, Patricia Monica. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Geofísica y Astronomía; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Centro de Investigaciones de la Geosfera y Biosfera. Universidad Nacional de San Juan. Facultad de Ciencias Exactas Físicas y Naturales. Centro de Investigaciones de la Geosfera y Biosfera; ArgentinaFil: Condori, Cristobal. Universidade do Brasília; BrasilFil: Lynner, Colton. University Of Delaware; Estados Unido

Fibrolipoma of the oral cavity - case report

O fibrolipoma é uma neoplasia benigna, caracterizada pela presença de células adiposas maduras, separadas por largas bandas de tecido conjuntivo fibroso denso. Esta patologia é uma variante microscópica do lipoma e pode acometer qualquer parte do corpo, no entanto, sua ocorrência em cavidade oral é infrequente. Em geral, é uma lesão de superfície lisa, base séssil ou pediculada, assintomática, de crescimento lento, coloração amarelada ou rósea quando mais profunda, mole a palpação, ocorrendo principalmente na mucosa jugal. Assim, o objetivo deste trabalho é descrever as principais características clínicas, histopatológicas e tratamento de um caso clínico de fibrolipoma. Paciente do sexo feminino, 67 anos, leucoderma, apresentava um nódulo pediculado de cor normocrômica, assintomático, firme a palpação, consistência fibrosa e superfície lisa, com tempo de evoluçã de aproximadamente dois anos, localizado em mucosa jugal esquerda. As hipóteses de diagnóstico foram de lipoma, fibroma, fenômeno de extravasamento de muco e fibroma de células gigantes. A paciente foi submetida a biópsia excisional e o exame histopatológico revelou o diagnóstico definitivo de fibrolipoma. O paciente encontra-se em proservação, sem sinal de recidiva. Conclui-se que, apesar de o fibrolipoma ser uma lesão benigna, o seu crescimento pode alcançar grandes dimensões, reforçando a necessidade de excisão cirúrgica. Deve também ressaltar a importância do exame histopatológico para diferenciar as variações histopalógicas do lipoma.Fibrolipoma is a benign neoplasm characterized by the presence of mature adipose cells separated by broad bands of dense fibrous connective tissue. This pathology is a microscopic variant of lipoma and can affect any part of the body. However, its occurrence in the oral cavity is uncommon. It is usually a smooth-surface lesion, asymptomatic, slow-growing, pedicled, asymptomatic, yellowish or pinkish color when deeper, soft on palpation, occurring mainly in the jugal mucosa. Thus, the aim of this paper is to describe the main clinical, histopathological and treatment characteristics of a clinical case of fibrolipoma. A 67-year-old female patient, leukoderma, had a normochromic, asymptomatic, firm palpation nodule, fibrous consistency, and smooth surface, with a time course of approximately two years, located in the left jugal mucosa. The diagnostic hypotheses were lipoma, fibroma, mucus extravasation phenomenon and giant cell fibroma. The patient underwent excisional biopsy and histopathological examination revealed the definitive diagnosis of fibrolipoma. The patient is in preservation, with no sign of relapse. It is concluded that, although fibrolipoma is a benign lesion, its growth can reach large dimensions, reinforcing the need for surgical excision. It should also emphasize the importance of histopathological examination to differentiate histopathological variations of lipoma

Ultra-Deep Sequencing Reveals the microRNA Expression Pattern of the Human Stomach

Background: While microRNAs (miRNAs) play important roles in tissue differentiation and in maintaining basal physiology, little is known about the miRNA expression levels in stomach tissue. Alterations in the miRNA profile can lead to cell deregulation, which can induce neoplasia. Methodology/Principal Findings: A small RNA library of stomach tissue was sequenced using high-throughput SOLiD sequencing technology. We obtained 261,274 quality reads with perfect matches to the human miRnome, and 42% of known miRNAs were identified. Digital Gene Expression profiling (DGE) was performed based on read abundance and showed that fifteen miRNAs were highly expressed in gastric tissue. Subsequently, the expression of these miRNAs was validated in 10 healthy individuals by RT-PCR showed a significant correlation of 83.97% (P<0.05). Six miRNAs showed a low variable pattern of expression (miR-29b, miR-29c, miR-19b, miR-31, miR-148a, miR-451) and could be considered part of the expression pattern of the healthy gastric tissue. Conclusions/Significance: This study aimed to validate normal miRNA profiles of human gastric tissue to establish a reference profile for healthy individuals. Determining the regulatory processes acting in the stomach will be important in the fight against gastric cancer, which is the second-leading cause of cancer mortality worldwide.Governo do Para/SEDECT/FAPESPAPROPESP/UFPAFADESPCAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior

Genomics and epidemiology for gastric adenocarcinomas (GE4GAC): a Brazilian initiative to study gastric cancer

Abstract Gastric cancer (GC) is the fifth most common type of cancer worldwide with high incidences in Asia, Central, and South American countries. This patchy distribution means that GC studies are neglected by large research centers from developed countries. The need for further understanding of this complex disease, including the local importance of epidemiological factors and the rich ancestral admixture found in Brazil, stimulated the implementation of the GE4GAC project. GE4GAC aims to embrace epidemiological, clinical, molecular and microbiological data from Brazilian controls and patients with malignant and pre-malignant gastric disease. In this letter, we summarize the main goals of the project, including subject and sample accrual and current findings

The Helicobacter pylori Genome Project : insights into H. pylori population structure from analysis of a worldwide collection of complete genomes

Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H. pylori subpopulations associated with the geographic origin of the host and with differential gastric disease risk. Here, we provide insights into H. pylori population structure as a part of the Helicobacter pylori Genome Project (HpGP), a multi-disciplinary initiative aimed at elucidating H. pylori pathogenesis and identifying new therapeutic targets. We collected 1011 well-characterized clinical strains from 50 countries and generated high-quality genome sequences. We analysed core genome diversity and population structure of the HpGP dataset and 255 worldwide reference genomes to outline the ancestral contribution to Eurasian, African, and American populations. We found evidence of substantial contribution of population hpNorthAsia and subpopulation hspUral in Northern European H. pylori. The genomes of H. pylori isolated from northern and southern Indigenous Americans differed in that bacteria isolated in northern Indigenous communities were more similar to North Asian H. pylori while the southern had higher relatedness to hpEastAsia. Notably, we also found a highly clonal yet geographically dispersed North American subpopulation, which is negative for the cag pathogenicity island, and present in 7% of sequenced US genomes. We expect the HpGP dataset and the corresponding strains to become a major asset for H. pylori genomics

Effects of long-term food restriction on genital reflexes in paradoxically sleep-deprived male rats

The purpose was to ascertain whether the different schedules of long-term food restriction (FR) exert influence on genital reflexes (penile erection-PE and ejaculation-EJ) induced by paradoxical sleep deprivation (PSD) in male rats. Diet restriction began at weaning with 6 g/day and food was increased by 1 g per week until reaching 15 g/day by adulthood. Rats submitted to FR and those fed ad libitum were distributed into PSD or maintained as control groups and challenged with saline or cocaine. the results indicated that PSD+saline induced PE and EJ in both ad libitum and FR groups, but cocaine only potentiated reflexes in ad libitum group. in an attempt to revert the effects of FR on genital reflexes, we provided food ad libitum to the restricted group during the PSD period (4 days). When compared to FR rats, an increase in the frequency of PE was observed in the FR group fed ad libitum during PSD (both groups were challenged with cocaine). Further, we sought to investigate motivational behavior by placing food within the behavioral cage during the evaluation of genital reflexes. the FR PSD+saline group challenged with food did not display genital reflexes but when injected with cocaine the responses were similar to those observed in FR PSD+cocaine rats not challenged with food. Our data suggest that the facilitatory effect of PSD on genital reflexes did not override the inhibitory effect of FR on erectile function, but different schedules of FR produce distinct effects on genital reflexes. Further studies are warranted to dissect the effect of food restriction on sexual behavior. (c) 2006 Elsevier B.V. All rights reserved.Universidade Federal de São Paulo, Dept Psychobiol, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Psychobiol, BR-04024002 São Paulo, BrazilWeb of Scienc

Velocidade de semeadura da soja Speed of sowing on soybean crop

Teve-se o objetivo de estudar a influência da velocidade da semeadura na cultura da soja, com sistemas dosadores de sementes dos tipos disco alveolado horizontal e pneumático. O delineamento experimental adotado foi o em blocos ao acaso, com 05 repetições. As velocidades de semeadura foram de 4; 6; 8; 10 e 12 km h-1. As variáveis avaliadas foram: população de plantas emergidas, distribuição longitudinal e os componentes de rendimento. Aplicou-se a regressão polinomial para os sistemas de disco alveolado horizontal e pneumático, em cada variável. As regressões só foram significativas para o sistema pneumático nos espaçamentos múltiplos e aceitáveis. Os componentes de rendimento da cultura da soja não se alteraram significativamente com o incremento da velocidade de semeadura até 12 km h-1 para os sistemas dosadores de sementes dos tipos disco alveolado horizontal e pneumático.<br>The objective was to study the influence of increasing the speed of sowing on the soybean crop, with horizontal seed plate and pneumatic seed distribution systems. The experimental design adopted was randomized block with 5 replicates. The sowing speeds were 4, 6, 8, 10 e 12 km h-1. The variables were: population of plants emerged, longitudinal distribution and components of yield. It was applied the polynomial regression for horizontal seed plate and pneumatic systems, for each variable. The regressions were significant only for the pneumatic system on longitudinal distribution. The components of soybean crop yield have not changed with the increase of the sowing speed until 12 km h-1 in the seed dispensing systems of horizontal and pneumatic plates