Coagulation and electrocoagulation for co-treatment of stabilized landfill leachate and municipal wastewater

Landfill leachate and municipal wastewater at various ratios (1:20, 1:10, 1:7 and 1:5) were subjected to coagulation and electrocoagulation (EC). Alum was used in conventional coagulation at pH 6 and aluminum plate as electrode was used in EC at a current density of 386 A/m2 with 5 cm inter electrode spacing. Treatment efficiency was assessed from removal of chemical oxygen demand (COD), total suspended solids (TSS), turbidity, ammonia, nitrate and phosphate. At 1:5 ratio of landfill leachate to municipal wastewater, highest COD removal was with 3.8 g/L alum whereas highest turbidity removal was with 3.3 g/L alum during coagulation. EC exhibited almost similar removal efficiency for all the parameters at different ratios tested except for COD which was considerably higher at 1:20 ratio. Aluminum consumption from electrode was 0.7 g/L following EC as compared to 3.8 g/L alum used in coagulation. The amount of sludge produced was found to be higher with EC as compared to coagulation which could be due to the fact that the electrochemical method was performed for a longer duration than conventional coagulation. For minimal sludge generation, EC reaction time should be ∼30 min. Further studies with EC process on costing and sludge generation will help to advance the technology for wastewater treatment

Temporal Patterns of Co-occurrence between Children's Self-regulatory Behaviour and their Private and Social Speech

The role of language has been identified as crucial in the cognitive development of young children, and has been observed on different time-scales. In particular, the real-time verbal mediation of behaviour has been studied in the context of private speech use and self-regulation, pioneered by Vygotsky and continued by others who followed this line of research. However previous studies have mainly attempted to find correlations between speech and self-regulatory behaviour, but have been unable to capture the dynamic and real-time temporal interactions between these phenomena. Hence, without being able to carry out a contextual analysis of the actual instances of temporal co-occurrence between speech and behaviour, correlational analysis is limited in determining the various kinds of verbal mediation that children spontaneously employ as strategies during problem-solving and while exercising self-regulation. The current study proposes ‘temporal pattern analysis’ as an effective method of extracting significantly recurring patterns of task-relevant speech and goal-directed behaviour, as they repeatedly occur in a stream of naturalistic behaviour which may also contain other temporally random events. These recurring temporal patterns are then contextually analysed, considering the pragmatic content of the speech involved and the goal-directedness of the behaviour towards a specific goal of the episode. Goal-directed episodes of behaviour in eight typically-developing preschool children were video-recorded during their self-initiated activities in the classroom as well as during a problem-solving task held in a laboratory setting. The proposed method of temporal and contextual analysis was used to examine the role of both private as well as social speech in the verbal mediation of self-regulatory behaviour during goal-attainment. A Contextual Model of Verbal Mediation was proposed in the study to account for the diverse functions that both social and private speech perform during verbal mediation of one’s own and others’ behaviour in a goal-directed setting, depending on the specific social and task-related context. A dynamic framework of assessment of performance was developed in the study, to account for both successful attempts at self-regulation as well as failures of self-regulation. The study also attempted to determine any consistent group differences in the styles of verbal mediation employed by the children, across the classroom and the laboratory settings.PhD was fully-funded for 3 years, jointly by the Cambridge Overseas Trust and the Lego Foundatio

Can coagulation–flocculation be an effective pre-treatment option for landfill leachate and municipal wastewater co-treatment?

Coagulation–flocculation as pre-treatment option for co-treatment of landfill leachate (LL) and municipal wastewater (MW) was investigated using ferric chloride as coagulant along with a novel flocculant namely polyacrylamide grafted gum ghatti (GGI-g-PAM). Experiment at different coagulant doses with constant flocculant dose was performed at different LL to MW at ratios of 1:20, 1:10, 1:7 and 1:5. Pre-treatment process's efficiency evaluation was based on removal of chemical oxygen demand (COD), total suspended solids (TSS), turbidity and colour. LL and MW characterization revealed that LL was old with low BOD5/COD ratio, high ammonia and TSS concentration while MW had moderate COD concentration. FeCl3 optimum dose was 970 mg/L with 100 mg/L of GGI-g-PAM flocculant. Best pre-treatment was at a ratio of 1:7 where 79% COD, 93% turbidity and 90% TSS removal was recorded. Colour removal was found to decrease with increase in FeCl3 dose at all the ratios tested except at 1:20. Results indicated that coagulation–flocculation can be useful pre-treatment option for LL and MW co-treatment

Coagulation and electrocoagulation for co-treatment of stabilized landfill leachate and municipal wastewater

Landfill leachate and municipal wastewater at various ratios (1:20, 1:10, 1:7 and 1:5) were subjected to coagulation and electrocoagulation (EC). Alum was used in conventional coagulation at pH 6 and aluminum plate as electrode was used in EC at a current density of 386 A/m2 with 5 cm inter electrode spacing. Treatment efficiency was assessed from removal of chemical oxygen demand (COD), total suspended solids (TSS), turbidity, ammonia, nitrate and phosphate. At 1:5 ratio of landfill leachate to municipal wastewater, highest COD removal was with 3.8 g/L alum whereas highest turbidity removal was with 3.3 g/L alum during coagulation. EC exhibited almost similar removal efficiency for all the parameters at different ratios tested except for COD which was considerably higher at 1:20 ratio. Aluminum consumption from electrode was 0.7 g/L following EC as compared to 3.8 g/L alum used in coagulation. The amount of sludge produced was found to be higher with EC as compared to coagulation which could be due to the fact that the electrochemical method was performed for a longer duration than conventional coagulation. For minimal sludge generation, EC reaction time should be ∼30 min. Further studies with EC process on costing and sludge generation will help to advance the technology for wastewater treatment

Co-treatment of old landfill leachate and municipal wastewater in sequencing batch reactor (SBR): Effect of landfill leachate concentration

Sequencing batch reactor (SBR) was assessed for direct co-treatment of old landfill leachate and municipal wastewater for chemical oxygen demand (COD), nutrients and turbidity removal. Nitrogen removal was achieved by sequential nitrification and denitrification under post-anoxic conditions. Initially, SBR operating conditions were optimized by varying hydraulic retention time (HRT) at 20% (v/v) landfill leachate concentration, and results showed that 6 d HRT was suitable for co-treatment. SBR performance was assessed in terms of COD, ammonia, nitrate, phosphate, and turbidity removal efficiency. pH, mixed liquor suspended solids, mixed liquor volatile suspended solids (MLVSS), and sludge volume index were monitored to evaluate stability of SBR. MLVSS indicated that biomass was able to grow even at higher concentrations of old landfill leachate. Ammonia and nitrate removal efficiency was more than 93% and 83%, respectively, whereas COD reduction was in the range of 60–70%. Phosphate and turbidity removal efficiency was 80% and 83%, respectively. Microbial growth kinetic parameters indicated that there was no inhibition of biomass growth up to 20% landfill leachate. The results highlighted that SBR can be used as an initial step for direct co-treatment of landfill leachate and municipal wastewater. © IWA Publishing 2016

Erythrocyte Membrane Cloaked Cytokine Functionalized Gold Nanoparticles Create Localized Controlled Inflammation for Rapid In Vitro Wound Healing

Due to impaired wound healing, millions of acute and chronic wound cases with increased morbidity have been recorded in the developed countries. The primary reason has been attributed to uncontrolled inflammation at the wound site, which makes healing impossible for years. The use of red blood cell (RBC) ghosts or erythrocyte membranes for different theranostic applications has gained significant attention in recent years due to their biocompatibility and biomimicking properties. Our study builds upon this concept by presenting a new approach for creating an improved and controlled inflammatory response by employing RBC ghost encapsulated tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) modified AuNPs (gold nanoparticles) for accelerating the wound healing at early postinjury stage (∼48 h). The results suggested that the developed GTNFα-IL6@AuNPs created a controlled and time dependent TNF-α response and showed increased reactive oxygen species generation at ∼12 h. Further, proper M1/M2 functional transition of macrophages was observed in macrophages at different time intervals. The expression results suggested that the levels of wound healing biomarkers like transforming growth factor-β (1.8-fold) and collagen (2.4-fold) increased while matrix metalloproteinase (3–8-fold) levels declined at later stages, which possibly increased the cell migration rate of NP treated cells to ∼90%. Hence, we are here reducing the timeline of the inflammatory phase of wound healing by actually creating a controlled inflammatory response at an early postinjury stage and further assisting in regaining the ability of cells for wound remodelation and repair. We intend that this new approach has the potential to improve the current treatment strategies for wound healing and skin repair under both in vitro and in vivo conditions