Evaluating the additive effect of Persica and chlorhexidine mouthwashes on oral health status of children receiving chemotherapy for their hematomalignancy : a randomized clinical trial

No definitive protocol has been introduced for treatment or prevention of chemotherapy induced mucositis. The aim of this study was to assess the additive effect of Persica and chlorhexidine on chemotherapy induced mucositis of children with hematomalignancies. This randomized clinical trial was performed on 44 children aged 6 to 12 years who were under a similar maintenance chemotherapy protocol for their hematomalignancies. The clinician instructed oral hygiene cares to the patients and their parents and the severity of the mucositis and oral health status of patients were evaluated according to Oral Assessment Guide index. Then, the patients were randomly assigned to one of two experimental groups and were instructed to rinse either with Persica oral drops or normal saline, twice a day for two weeks. Subsequently, the patients in both groups were educated to rinse with chlorhexidine for 30 seconds and avoid eating for an hour. Second and third oral examinations were performed on the 8th and 15th day using the same questionnaire. Comparing severity of mucositis and oral health status of patients did not show any significant difference between treatment groups in either of examination sessions (p>0.05). However, both treatment groups showed statistically significant oral health improvement, in terms of mucositis, plaque accumulation and gingival condition, in 14 days following mouthrinses administration (p<0.05). Both mouth-rinse combinations were effective on mucositis, plaque and gingival status of children receiving chemotherapy. However, Persica does not seem to pose additional effect on chlorhexidine in decreasing severity of chemotherapy induced mucositis

Knowledge of General Dentists and Senior Dental Students about Indications of Antibiotic Prophylaxis in Yazd, Iran

Introduction: In patients susceptible to infection, after dental procedures which lead to soft tissue manipulation or bleeding, the occurrence of bacteremia is probable. Hence, antibiotic prophylaxis is very important in this group of patients. The purpose of this study was to assess the level of awareness of senior dental students and general dental practitioners in the city of Yazd about the indications of antibiotics prophylaxis and the proper way of prescribing the prophylactic regimens. Materials and methods: This study is a cross-sectional descriptive-analytical study. To collecting data, prepared questionnaires distributed among 60 general dentists and 60 senior students. Results: The mean of knowledge scores of senior dental students and general dentists were 55.43  and 55.06  respectively. Both groups showed acceptable levels of knowledge. Conclusion: The levels of knowledge of senior dental students and general dental practitioners were desirable and this may be due to the participation of practitioners in relevant re-training programs or allocation of related academic resources in this area during their education

Craniofacial polyostotic fibrous dysplasia: A rare case

Craniofacial fibrous dysplasia (FD) is one of three types of FD which can affect the craniofacial complex. It is the proliferation of cellular fibrous connective tissue intermixed with irregular bony trabecules. It is a developmental tumor-like condition that is characterized by replacement of normal bone. The purpose of this report is to present a rare case of craniofacial polyostotic FD that led to vision loss in the same affected side