Rate baladeuse associée à une anomalie de Neuhauser: à propos d’un cas

La rate baladeuse est une entité anatomique rare pouvant être d’origine congénitale ou acquise. Son diagnostic se fait souvent suite à une torsion de son pédicule ou fortuitement lors d’un examen d’imagerie. L’association à une autre anomalie congénitale est exceptionnelle et n’a pas été décrite dans la littérature. Nous rapportant le cas d’une association d’une rate pelvienne à une anomalie de Neuhauser longtemps asymptomatiques et de découverte fortuite lors d’une TDM thoraco-abdomino-pelvienne faite dans le cadre d’un bilan d’extension d’un adénocarcinome chez un homme de 86 ans.Pan African Medical Journal 2016; 2

In vivo evaluations of wound healing and anti microbial properties of tualang honey using a full thickness burn wound in sprague dawley rats

The bum wound serves as a portal of entry for colonizing opportunistic microorganisms which can affect wound healing. The effect of Tualang honey on wound healing in the bacterial contaminated full-thickness bum wounds was evaluated in this study. The objectives of this study is to evaluate the wound contraction, antimicrobial properties and histological aspects of Tualang honey in treating full thickness bum wounds in a rat model in comparison to Chitosan gel or Aquacel-Ag®. The effect ofTualang honey on wound healing in the full-thickness bum wounds was evaluated in 36 male Sprague Dawley rats. The rats were randomly divided into 3 groups (n=l2/group). Rat were anesthetized, and three full thickness bum wounds were created on each rat using a modified metal screwdriver heated using flame from blow torch. Each group of rats was inoculated with a different organism in the bum wounds: Group A was inoculated with Pseudomonas aentginosa, Group B was inoculated with Klebsiella pneumoniae and Group C was inoculated with Acinetobacter baumanii. One wound on each rat was dressed with either Tualang honey, Chitosan gel or Aquacel-Ag®. The rats were subjected to the evaluation period of 3, 6, 7, 9, 12, 14, 15, 18 and 21 days, where the wow1d size, microbiological and histological findings were assessed. The results of this study revealed that the mean wound size of the Tualang honey-treated wounds was not statistically different than those of the Chitosan gel or Aquacel-Ag® treated wounds when the wounds were compared throughout the entire expetiment (P> 0.05). However, comparing the mean wound size on day 21 alone revealed that the Tualang honey-treated wounds were smaller in comparison to that of the Chitosan gel and Aquacel-Ag® treated groups. The quantitative and semi-quantitative methods showed that there was a significant reduction in The bum wound serves as a portal of entry for colonizing opportunistic microorganisms which can affect wound healing. The effect of Tualang honey on wound healing in the bacterial contaminated full-thickness bum wounds was evaluated in this study. The objectives of this study is to evaluate the wound contraction, antimicrobial properties and histological aspects of Tualang honey in treating full thickness bum wounds in a rat model in comparison to Chitosan gel or Aquacel-Ag®. The effect ofTualang honey on wound healing in the full-thickness bum wounds was evaluated in 36 male Sprague Dawley rats. The rats were randomly divided into 3 groups (n=l2/group). Rat were anesthetized, and three full thickness bum wounds were created on each rat using a modified metal screwdriver heated using flame from blow torch. Each group of rats was inoculated with a different organism in the bum wounds: Group A was inoculated with Pseudomonas aentginosa, Group B was inoculated with Klebsiella pneumoniae and Group C was inoculated with Acinetobacter baumanii. One wound on each rat was dressed with either Tualang honey, Chitosan gel or Aquacel-Ag®. The rats were subjected to the evaluation period of 3, 6, 7, 9, 12, 14, 15, 18 and 21 days, where the wow1d size, microbiological and histological findings were assessed. The results of this study revealed that the mean wound size of the Tualang honey-treated wounds was not statistically different than those of the Chitosan gel or Aquacel-Ag® treated wounds when the wounds were compared throughout the entire expetiment (P> 0.05). However, comparing the mean wound size on day 21 alone revealed that the Tualang honey-treated wounds were smaller in comparison to that of the Chitosan gel and Aquacel-Ag® treated groups. The quantitative and semi-quantitative methods showed that there was a significant reduction in bactetial growth in Tualang honey treated wounds compared to Chitosan gel and AquacelAg ® treated wounds in Group A and C. There was no statistically significant difference in the granulation tissue fonnation and epidennal thickness between the Tualang honey, Chitosan gel or Aquacel-Ag® treated wound when they were compared throughout the study. Nevertheless, early granulation tissue fonnation and epithelialization was seen in Tualang honey treated wounds by day 14 in bum wounds infected with Pseudomonas aeruginosa. In conclusions, clinical examination of the wounds and histological evaluation showed that Tualang honey gave the fastest rate of healing, the least inflammatory reaction and has most rapid neovascularisation compared with the other treatments. Tualang honey also provide good evidence of the effectiveness of the antibacterial activity of honey on burn wounds infected with Pseudomonas aeruginosa and Acinetobacter baumanii

Cardiovascular risks and primary interventions among treated rheumatoid arthritis patients: Experience from a tertiary care centre in Kuala Lumpur, Malaysia

Purpose: To investigate the cardiovascular risk among treated rheumatoid arthritis (RA) patients to predict the factors associated with high cardiovascular risk and to determine the presence of pharmacotherapy primary prevention among treated RA patients with high cardiovascular disease (CVD) risk.Methods: The study was a prospective cross-sectional study on adult patients diagnosed and treated for RA and without established heart disease/stroke. Cardiovascular risk scoring was based on Framingham Cardiovascular Disease 10-year risk prediction model (BMI model) x 1.5 factor while descriptive and inferential analyses were done using SPSS.Results: High CVD risk was defined as FRS-CVD cardiovascular risk categories (>20%) and 55.9% of patients were at high CVD risk. Use of Hydroxychloroquine (OR: 0.44; 95 % CI: 0.21- 0.92; p= 0.028) and COX-2 inhibitors (OR: 0.31; 95% CI:0.10- 0.95; p = 0.039) were found to be significantly associated with high CVD risk among treated RA patients. Significant number of high CVD risk patients did receive pharmacotherapy primary prevention (p = 0.001).Conclusion: Hydroxychloroquine and COX-2 inhibitors are independent negative risk predictors associated with high CVD risk among treated RA patients. Baseline cardiovascular risk data may be useful in rational use of medications to treat RA, considering that cardiovascular related mortality is the leading cause of death in RA

Crack growth study under thermo-mechanical loads: parametric analysis for 2024 T3 aluminum alloy

Due to their severe operating conditions, many industrial components are subjected to complex combinations of cyclic mechanical stresses and thermal pressures. These combinations are responsible for the initiation and propagation of fatigue cracks in these parts, which can lead to failure. Thus, the study of the fatigue strength of these parts in such conditions becomes essential because it allows us to predict the life and safety of components.    This study examines the influence of the load ratio and temperature on the propagation rate of long cracks on the outer surface. The propagation of a fatigue crack in ABAQUS was therefore automatically simulated using an identified Paris law of 2024 T3 aluminium alloy. Therefore, the study of these components' fatigue resistance in such conditions becomes essential to predict the service life and safety of the components

Clinical Study and Molecular Genetic Analyses of Malaysian GEFS+ Patients

Generalized epilepsy with febrile seizure plus (GEFS+) is a familial epilepsy syndrome characterized by phenotypic and genetic heterogeneity. Neuronal voltage gated sodium channel α-1 subunit gene, SCN1A is the most clinically relevant and associated with GEFS+. The objective was to study the clinical presentations of GEFS+ and analyze the SCN1A gene associated with Malaysian GEFS+ patients. Blood samples were collected from 30 unrelated GEFS+ patients and genomic DNA was obtained using the Qiagen DNA Blood Mini Kit following the manufacturer’s instructions. The 26 exons of SCN1A genes were analyzed by polymerase chain reaction (PCR) and denaturing high performance liquid chromatography (DHPLC). The aberrant profile peak from DHPLC analysis was confirmed by direct sequencing. The spectrum of phenotypes observed in Malaysian GEFS+ patients included febrile seizure (FS), febrile seizure plus (FS+) and afebrile generalized tonic clonic seizure (AGTCS). Direct sequencing of SCN1A revealed seven sequence variants including one novel SCN1A mutation that was associated with GEFS+. This suggests that mutation of the SCN1A gene is one of the prevalent causes of GEFS+ in Malaysia

Effect of GPS tropospheric delay Neill mapping function simplification

The mathematical modeling on the mapping function models should be revised and also simplified to improve the calculation of the GPS tropospheric delay. The zenith tropospheric delay can be amplified by a coefficient factor called mapping function to form total tropospheric delay. There are many mapping functions have been established to calculate the scale factor which can affect the total tropospheric delay. Most of the modern models have separated mapping functions for the hydrostatic and the wet part. Recently, the developed tropospheric delay models use mapping functions in the form of continued fractions which is quite tedious in calculation. There are 26 mathematical operations for Neill Mapping Function (NMF) to be done before getting the mapping function scale factor. There is a need to simplify the mapping function models to allow faster calculation and also better understanding of the models. The mapping functions for NMF models for hydrostatic and wet components are given in a form of continued fraction, whereby the elevation angle is the variable. These mapping function models have been selected to be simplified, because of their ability to achieve mapping function scale factor, down to 3 degree of elevation angle

Hierarchical Segmentation of the Malawi Rift: The Influence of Inherited Lithospheric Heterogeneity and Kinematics in the Evolution of Continental Rifts

We used detailed analysis of Shuttle Radar Topography Mission-digital elevation model and observations from aeromagnetic data to examine the influence of inherited lithospheric heterogeneity and kinematics in the segmentation of largely amagmatic continental rifts. We focused on the Cenozoic Malawi Rift, which represents the southern extension of the Western Branch of the East African Rift System. This north trending rift traverses Precambrian and Paleozoic-Mesozoic structures of different orientations. We found that the rift can be hierarchically divided into first-order and second-order segments. In the first-order segmentation, we divided the rift into Northern, Central, and Southern sections. In its Northern Section, the rift follows Paleoproterozoic and Neoproterozoic terrains with structural grain that favored the localization of extension within well-developed border faults. The Central Section occurs within Mesoproterozoic-Neoproterozoic terrain with regional structures oblique to the rift extent. We propose that the lack of inherited lithospheric heterogeneity favoring extension localization resulted in the development of the rift in this section as a shallow graben with undeveloped border faults. In the Southern Section, Mesoproterozoic-Neoproterozoic rocks were reactivated and developed the border faults. In the second-order segmentation, only observed in the Northern Section, we divided the section into five segments that approximate four half-grabens/asymmetrical grabens with alternating polarities. The change of polarity coincides with flip-over full-grabens occurring within overlap zones associated with ∼150 km long alternating border faults segments. The inherited lithospheric heterogeneity played the major role in facilitating the segmentation of the Malawi Rift during its opening resulting from extension

Effect of dust on the operation of photovoltaic solar panels installed in the Hodna region - Experimental study

In this work, an experimental study of the effect of dust on the operation of photovoltaic solar panels was conducted in the Hodna region. For this, a monocrystalline type of solar panel was tested with a power of 100W. A quantity of dust was scattered for the first tests during the month of March 2022, then the voltage and current were measured. The second tests were conducted under outdoor M’sila conditions for two months. The results obtained show that the accumulation of dust on the surface of the panels reduces the passage of solar radiation on the one hand, and leads to a rise in the temperature of the panels on the other hand, which reduces the energy produced by the photovoltaic system. Therefore, periodic cleaning of photovoltaic solar panels is necessary