2,260 research outputs found

    An economic survey of New Zealand wheatgrowers : survey no. 2

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    This is survey number 2. No. 1 was know as "National wheatgrowers' survey"This Report is the second in an annual series of economic surveys of New Zealand wheatgrowing farms. These surveys have been undertaken by the Agricultural Economics Research Unit at Lincoln College on behalf of Wheat Growers Sub-Section of Federated Farmers of New Zealand Inc. Specific attention has been focused on the physical characteristics of wheatgrowing farms, the area of wheat and other crops sown, wheat yields, cultural practices and costs and returns for the 1977/78 wheat crop. An attempt has also been made to allocate plant and machinery overhead costs to the wheat enterprise on both an historical and current cost basis. The need for current and detailed information from the Survey involved two visits to the farms in the sample; one in the spring following drilling and the second in the autumn after harvest

    Effect of propranolol on facial processing in autism spectrum disorder

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    Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social interaction deficits, communication impairments, and restricted, repetitive behaviors. ASD, with estimates of incidence as high as 1 in 88 individuals, has a largely unknown etiology. Pharmacological intervention is currently being explored to improve symptoms of ASD, including those in the social domain. Social interaction deficits in this population may include facial processing abnormalities, such as reduced eye contact, and increased fixation on less socially-salient facial regions, such as the mouth. However, there is variability in the degree of these deficits in the current literature. Additionally, it has been previously hypothesized that stress mediates poor facial processing in individuals with ASD. This pilot study examines the effect of propranolol, a nonselective beta-adrenergic antagonist anxiolytic, on facial processing in individuals with ASD and typically developing controls

    Continuous GPS Observations of Postseismic Deformation Following the 16 October 1999 Hector Mine, California, Earthquake (M_w 7.1)

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    Rapid field deployment of a new type of continuously operating Global Positioning System (GPS) network and data from Southern California Integrated GPS Network (SCIGN) stations that had recently begun operating in the area allow unique observations of the postseismic deformation associated with the 1999 Hector Mine earthquake. Innovative solutions in fieldcraft, devised for the 11 new GPS stations, provide high-quality observations with 1-year time histories on stable monuments at remote sites. We report on our results from processing the postseismic GPS data available from these sites, as well as 8 other SCIGN stations within 80 km of the event (a total of 19 sites). From these data, we analyze the temporal character and spatial pattern of the postseismic transients. Data from some sites display statistically significant time variation in their velocities. Although this is less certain, the spatial pattern of change in the postseismic velocity field also appears to have changed. The pattern now is similar to the pre-Landers (pre-1992) secular field, but laterally shifted and locally at twice the rate. We speculate that a 30 km × 50 km portion of crust (near Twentynine Palms), which was moving at nearly the North American plate rate (to within 3.5 mm/yr of that rate) prior to the 1992 Landers sequence, now is moving along with the crust to the west of it, as though it has been entrained in flow along with the Pacific Plate as a result of the Landers and Hector Mine earthquake sequence. The inboard axis of right-lateral shear deformation (at lower crustal to upper mantle depth) may have jumped 30 km farther into the continental crust at this fault junction that comprises the southern end of the eastern California shear zone

    Association of subcortical gray-matter volumes with life-course-persistent antisocial behavior in a population-representative longitudinal birth cohort

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    Neuropsychological evidence supports the developmental taxonomy theory of antisocial behavior, suggesting that abnormal brain development distinguishes life-course-persistent from adolescence-limited antisocial behavior. Recent neuroimaging work confirmed that prospectively-measured life-course-persistent antisocial behavior is associated with differences in cortical brain structure. Whether this extends to subcortical brain structures remains uninvestigated. This study compared subcortical gray-matter volumes between 672 members of the Dunedin Study previously defined as exhibiting life-course-persistent, adolescence-limited or low-level antisocial behavior based on repeated assessments at ages 7-26 years. Gray-matter volumes of 10 subcortical structures were compared across groups. The life-course-persistent group had lower volumes of amygdala, brain stem, cerebellum, hippocampus, pallidum, thalamus, and ventral diencephalon compared to the low-antisocial group. Differences between life-course-persistent and adolescence-limited individuals were comparable in effect size to differences between life-course-persistent and low-antisocial individuals, but were not statistically significant due to less statistical power. Gray-matter volumes in adolescence-limited individuals were near the norm in this population-representative cohort and similar to volumes in low-antisocial individuals. Although this study could not establish causal links between brain volume and antisocial behavior, it constitutes new biological evidence that all people with antisocial behavior are not the same, supporting a need for greater developmental and diagnostic precision in clinical, forensic, and policy-based interventions

    Early risk factors for adolescent antisocial behaviour: an Australian longitudinal study

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    Objective: This investigation utilizes data from an Australian longitudinal study to identify early risk factors for adolescent antisocial behaviour. Method: Analyses are based on data from the Mater University Study of Pregnancy, an on-going longitudinal investigation of women’s and children’s health and development involving over 8000 participants. Five types of risk factors (child characteristics, perinatal factors, maternal/familial characteristics, maternal pre- and post-natal substance use and parenting practices) were included in analyses and were based on maternal reports, child assessments and medical records. Adolescent antisocial behaviour was measured when children were 14 years old, using the delinquency subscale of the Child Behaviour Checklist. Results: Based on a series of logistic regression models, significant risk factors for adolescent antisocial behaviour included children’s prior problem behaviour (i.e. aggression and attention/restlessness problems at age 5 years) and marital instability, which doubled or tripled the odds of antisocial behaviour. Perinatal factors, maternal substance use, and parenting practices were relatively poor predictors of antisocial behaviour. Conclusions: Few studies have assessed early predictors of antisocial behaviour in Australia and the current results can be used to inform prevention programs that target risk factors likely to lead to problem outcomes for Australian youth

    Which executive functioning deficits are associated with AD/HD, ODD/CD and comorbid AD/HD+ODD/CD?

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    Item does not contain fulltextThis study investigated (1) whether attention deficit/hyperactivity disorder (AD/HD) is associated with executive functioning (EF) deficits while controlling for oppositional defiant disorder/conduct disorder (ODD/CD), (2) whether ODD/CD is associated with EF deficits while controlling for AD/HD, and (3)~whether a combination of AD/HD and ODD/CD is associated with EF deficits (and the possibility that there is no association between EF deficits and AD/HD or ODD/CD in isolation). Subjects were 99~children ages 6–12 years. Three putative domains of EF were investigated using well-validated tests: verbal fluency, working memory, and planning. Independent of ODD/CD, AD/HD was associated with deficits in planning and working memory, but not in verbal fluency. Only teacher rated AD/HD, but not parent rated AD/HD, significantly contributed to the prediction of EF task performance. No EF deficits were associated with ODD/CD. The presence of comorbid AD/HD accounts for the EF deficits in children with comorbid AD/HD+ODD/CD. These results suggest that EF deficits are unique to AD/HD and support the model proposed by R. A. Barkley (1997).17 p

    Developmental links between trajectories of physical violence, vandalism, theft, and alcohol-drug use from childhood to adolescence

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    Differences in developmental trajectories of physical violence, vandalism, theft, and alcohol-drug use from ages 10 to 15 were studied. For females and for males, three trajectories of theft and of alcohol-drug use increased from 10 years to 15 years, while only the high trajectory of vandalism increased from ten to 14. All trajectories of physical violence decreased. Children who engaged in the high trajectories of vandalism, theft, and alcohol-drug use had a high probability of also being high in physical violence. Compared to males, females were less likely to be on the high trajectory of physical violence, and their trajectories of other antisocial behaviors were less strongly associated with high levels of physical violence. The results suggest that physical violence during pre-adolescence and adolescence has a different developmental pattern than other forms of antisocial behavior, and that its relation to these other forms of antisocial behavior differs by se

    Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon

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    AIMS/HYPOTHESIS: Long-term exposure to NEFAs leads to inhibition of glucose-induced insulin secretion. We tested whether the release of somatostatin and glucagon, the two other major islet hormones, is also affected. METHODS: Mouse pancreatic islets were cultured for 72 h at 4.5 or 15 mmol/l glucose with or without 0.5 mmol/l oleate or palmitate. The release of glucagon and somatostatin during subsequent 1 h incubations at 1 or 20 mmol/l glucose as well as the islet content of the two hormones were determined. Lipid-induced changes in islet cell ultrastructure were assessed by electron microscopy. RESULTS: Culture at 15 mmol/l glucose increased islet glucagon content by approximately 50% relative to that observed following culture at 4.5 mmol/l glucose. Inclusion of oleate or palmitate reduced islet glucagon content by 25% (at 4.5 mmol/l glucose) to 50% (at 15 mmol/l glucose). Long-term exposure to the NEFA increased glucagon secretion at 1 mmol/l glucose by 50% (when islets had been cultured at 15 mmol/l glucose) to 100% (with 4.5 mmol/l glucose in the culture medium) and abolished the inhibitory effect of 20 mmol/l glucose on glucagon secretion. Somatostatin content was unaffected by glucose and lipids, but glucose-induced somatostatin secretion was reduced by approximately 50% following long-term exposure to either of the NEFA, regardless of whether the culture medium contained 4.5 or 15 mmol/l glucose. Ultrastructural evidence of lipid deposition was seen in <10% of non-beta cells but in >80% of the beta cells. CONCLUSIONS/INTERPRETATION: Long-term exposure to high glucose and/or NEFA affects the release of somatostatin and glucagon. The effects on glucagon secretion are very pronounced and in type 2 diabetes in vivo may aggravate the hyperglycaemic effects due to lack of insulin

    Expressive and Instrumental Offending: Reconciling the Paradox of Specialisation and Versatility

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    Although previous research into specialisation has been dominated by the debate over the existence of specialisation versus versatility, it is suggested that research needs to move beyond the restrictions of this dispute. The current study explores the criminal careers of 200 offenders based on their criminal records, obtained from a police database in the North West of England, aiming to understand the patterns and nature of specialisation by determining the presence of differentiation within their general offending behaviours and examining whether the framework of Expressive and Instrumental offending styles can account for any specialised tendencies that emerge. Fifty-eight offences were subjected to Smallest Space Analysis. Results revealed that a model of criminal differentiation could be identified and that any specialisation is represented in terms of Expressive and Instrumental offending styles
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