1 research outputs found
Actively caseating endobronchial tuberculosis successfully treated with intermittent chemotherapy without corticosteroid: a report of 2 cases
Tuberculous infection of the tracheobronchial tree confirmed by microbiological or histopathological evidence with or without
parenchymal involvement is known as endobronchial tuberculosis. Chronic cough is the predominant symptom. Expectorated
sputum examination for acid fast bacilli is often negative leading to delay in diagnosis. Therefore, bronchoscopy is crucial for early
diagnosis and evaluation of the extent of disease. Bronchostenosis is a significant complication of endobronchial tuberculosis
that may be present at the time of diagnosis or develops during the course of treatment. Previously, corticosteroids have been
used along with antitubercular therapy to prevent or reduce the extent of bronchostenosis; however, their role is debatable as
bronchostenosis often develops despite the use of corticosteroids. Furthermore, the duration of treatment varied from 6β9 months
of daily therapy in previous series and little is known about efficacy of intermittent antituberculous therapy. Here we report two
cases of actively caseating endobronchial tuberculosis successfully managed with six months of intermittent oral antitubercular
therapy without corticosteroids