Evaporation of aqueous salt solutions in sandstone during dissolution/crystallization cycles

COMInternational audienc

Salt weathering of sandstone during drying : effect of primary and secondary crystallisation

ACTInternational audienc

Mental Health and Work:Achieving Well-integrated Policies and Service Delivery

Mental ill-health can lead to poor work performance, high sickness absence and reduced labour market participation, resulting in considerable costs for society.Improving labour market participation of people with mental health problems requires well-integrated policies and services across the education, employment, health and social sectors. This paper provides examples of policy initiatives from 10OECDcountries for integrated services. Outcomes and strengths and weaknesses of the policy initiatives are presented, resulting in the following main conclusions for future integrated mental health and work policies and services: - More rigorous implementation and evaluation of integrated policies is necessary to improve labour market outcomes. Implementation cannot be left to the discretion of stakeholders only. - Better financial incentives and clearer obligations and guidelines need to be provided to stakeholders and professionals to participate in integrated service delivery. - Each sector has a responsibility to assure integrated services in line with client needs, in turn requiring much better knowledge about the needs of clients with a mental illness. - More integrated provision of services within each sector–e.g. through employment advice brought into the mental health system and psychological expertise brought into employment services –appears to be the easiest and most cost-effective approach

Salt crystallization dynamics in building rocks: a 4D study using laboratory X-ray micro-CT

We employ laboratory X-ray micro-computed tomography (μCT) during climate-controlled salt weathering experiments to acquire data on the kinetics of drying and salt precipitation and the distribution of crystals within the pore space of Mšené sandstone. For that purpose, a custom-designed setup was built at the UGCT’s scanners of the Ghent University Centre for X-ray Tomography (UGCT) that allows to acquire 4D scans while drying. Samples were initially capillary saturated with a saturated NaCl-solution and subsequently dried at 20% RH and at 50% RH, at room temperature. These RH-values are representative for winter and summer conditions for the salt NaCl, which is not temperature sensitive. Different salt precipitation dynamics result in different drying kinetics at the two RH’s. These crystallization and transport dynamics can be directly linked as revealed by the 4D X-ray μCT datasets

Impact of recrystallization cycles on drying of salt contaminated porous media

COMInternational audienc

Nuorten palvelut syynissä

Opetus- ja kulttuuriministeriö, sosiaali- ja terveysministeriö ja työ- ja elinkeinoministeriö tilasivat OECD:ltä arvioinnin nuorten palveluista. Arvioinnissa keskityttiin erityisesti nuorten koulutukseen ja työelämään siirtymisen. Arviointi toteutettiin keväällä 2018. Arviointi on osa OECD:n Action Plan for Youth -toimintapolitiikkaohjelman toteuttamista. Raportti sisältää suosituksia nuorten palvelujen kehittämiseksi. Raportti keskittyy nuorten siirtymiseen koulutuksesta työhön sekä nuorille suunnattujen avustuksien ja monialaisten palvelujen kehittämiseen ja vahvistamiseen. Vastaavia raportteja löytyy myös muista Pohjoismaista. OECD:n tuottaman arviointiraportin kokonaisuudessaan voit käydä lukemassa osoitteesta: https://www.oecd-ilibrary.org/employment/investing-in-youth_24126357 Tässä julkaisussa on suomennettu arviointiraportin tiivistelmäluku ja suositukset. Käännös on opetus- ja kulttuuriministeriön teettämä. Raporttia ei kokonaisuudessaan julkaista suomeksi ja ruotsiksi. Arviointiraportin tekijänoikeuden kuuluvat OECD:lle

Canonical Wnt signaling negatively modulates regulatory T cell function

Foxp3 is crucial for both the development and function of regulatory T (Treg) cells; however, the posttranslational mechanisms regulating Foxp3 transcriptional output remain poorly defined. Here, we demonstrate that Tcell factor 1 (TCF1) and Foxp3 associates in Treg cells and that active Wnt signaling disrupts Foxp3 transcriptional activity. A global chromatin immunoprecipitation sequencing comparison in Treg cells revealed considerable overlap between Foxp3 and Wnt target genes. The activation of Wnt signaling reduced Treg-mediated suppression both invitro and invivo, whereas disruption of Wnt signaling in Treg cells enhanced their suppressive capacity. The activation of effector Tcells increased Wnt3a production, and Wnt3a levels were found to be greatly increased in mononuclear cells isolated from synovial fluid versus peripheral blood of arthritis patients. We propose a model in which Wnt produced under inflammatory conditions represses Treg cell function, allowing a productive immune response, but, if uncontrolled, could lead to the development of autoimmunity

VectorNet Data Series 3: Culicoides Abundance Distribution Models for Europe and Surrounding Regions

This is the third in a planned series of data papers presenting modelled vector distributions produced during the ECDC and EFSA funded VectorNet project. The data package presented here includes those Culicoides vectors species first modelled in 2015 as part of the VectorNet gap analysis work namely C. imicola, C. obsoletus, C. scoticus, C. dewulfi, C. chiopterus, C. pulicaris, C. lupicaris, C. punctatus, and C. newsteadi. The known distributions of these species within the Project area (Europe, the Mediterranean Basin, North Africa, and Eurasia) are currently incomplete to a greater or lesser degree. The models are designed to fill the gaps with predicted distributions, to provide a) first indication of vector species distributions across the project geographical extent, and b) assistance in targeting surveys to collect distribution data for those areas with no field validated information. The models are based on input data from light trap surveillance of adult Culicoides across continental Europe and surrounding regions (71.8°N –33.5°S, – 11.2°W – 62°E), concentrated in Western countries, supplemented by transect samples in eastern and northern Europe. Data from central EU are relatively sparse.Peer reviewe

Publishing data to support the fight against human vector-borne diseases

Vector-borne diseases are responsible for more than 17% of human cases of infectious diseases. In most situations, effective control of debilitating and deadly vector-bone diseases (VBDs), such as malaria, dengue, chikungunya, yellow fever, Zika and Chagas requires up-to-date, robust and comprehensive information on the presence, diversity, ecology, bionomics and geographic spread of the organisms that carry and transmit the infectious agents. Huge gaps exist in the information related to these vectors, creating an essential need for campaigns to mobilise and share data. The publication of data papers is an effective tool for overcoming this challenge. These peer-reviewed articles provide scholarly credit for researchers whose vital work of assembling and publishing well-described, properly-formatted datasets often fails to receive appropriate recognition. To address this, GigaScience 's sister journal GigaByte partnered with the Global Biodiversity Information Facility (GBIF) to publish a series of data papers, with support from the Special Programme for Research and Training in Tropical Diseases (TDR), hosted by the World Health Organisation (WHO). Here we outline the initial results of this targeted approach to sharing data and describe its importance for controlling VBDs and improving public health