3,334 research outputs found
Dimerization-Induced Fermi-Surface Reconstruction in IrTe2
We report a de Haas-van Alphen (dHvA) oscillation study on IrTe2 single crystals showing complex dimer formations. By comparing the angle dependence of dHvA oscillations with band structure calculations, we show distinct Fermi surface reconstruction induced by a 1/5-type and a 1/8-type dimerizations. This verifies that an intriguing quasi-two-dimensional conducting plane across the layers is induced by dimerization in both cases. A phase transition to the 1/8 phase with higher dimer density reveals that local instabilities associated with intra-and interdimer couplings are the main driving force for complex dimer formations in IrTe2.X11149sciescopu
Kinetic stabilization of Fe film on (4 by 2)-GaAs(100)
We grow Fe film on (4 by 2)-GaAs(100) at low temperature, (~ 130 K) and study
their chemical structure by photoelectron spectroscopy using synchrotron
radiation. We observe the effective suppression of As segregation and
remarkable reduction of alloy formation near the interface between Fe and
substrate. Hence, this should be a way to grow virtually pristine Fe film on
GaAs(100). Further, the Fe film is found stable against As segregation even
after warmed up to room temperature. There only forms very thin, ~ 8 angstrom
thick interface alloy. It is speculated that the interface alloy forms via
surface diffusion mediated by interface defects formed during the low
temperature growth of the Fe film. Further out-diffusion of both Ga and As are
suppressed because it should then proceed via inefficient bulk diffusion.Comment: 4 figure
Highly Scalable Synthesis of MoS2 Thin Films with Precise Thickness Control via Polymer-Assisted Deposition
1112Ysciescopu
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
The osteoblast differentiation capacity of skeletal stem cells (SSCs) must be tightly regulated, as inadequate bone formation results in low bone mass and skeletal fragility, and over-exuberant osteogenesis results in heterotopic ossification (HO) of soft tissues. RUNX2 is essential for tuning this balance, but the mechanisms of posttranslational control of RUNX2 remain to be fully elucidated. Here, we identify that a CK2/HAUSP pathway is a key regulator of RUNX2 stability, as Casein kinase 2 (CK2) phosphorylates RUNX2, recruiting the deubiquitinase herpesvirus-associated ubiquitin-specific protease (HAUSP), which stabilizes RUNX2 by diverting it away from ubiquitin-dependent proteasomal degradation. This pathway is important for both the commitment of SSCs to osteoprogenitors and their subsequent maturation. This CK2/HAUSP/RUNX2 pathway is also necessary for HO, as its inhibition blocked HO in multiple models. Collectively, active deubiquitination of RUNX2 is required for bone formation and this CK2/HAUSP deubiquitination pathway offers therapeutic opportunities for disorders of inappropriate mineralization
THE EFFECTS OF WEARING ROLLER SHOES ON GROUND REACTION FORCE CHARACTERISTICS DURING WALKING
Roller shoes have become increasingly popular among children and it features retractable wheels which allowing the user to walk or roll without changing the footwear. Maintaining balance during forward walking with roller shoes is not an easy task. To prevent falling backward, the user needs to lock the knees and tighten the ankles and thighs while the upper body is slightly leaning forward. Constant walking with roller shoes forces the user to walk in a manner much different from normal gait. Prolonged exposure to un-natural stresses on human body forces our body to evolve by strengthening those incorrect, and temporary functions (Clement et aI., 1981). For children, the chronic stress may lead to serious injuries in the lower extremity later in life. If any potential' of injury exists in a movement it is critical to examine the associated forces that may lead to injury. To the best of our knowledge, the effects of wearing roller shoes on ground reaction forces (GRF) characteristics have rarely been studied, especially in the youth population. Thus, the purpose of this study was to compare GRF characteristics during walking wearing jogging and roller shoes
Public Transportation Service Evaluations Utilizing Seoul Transportation Card Data
AbstractThis study evaluated transit service performance in Seoul using data collected from the Automatic Fare Collection (AFC) system in Seoul. The distance-based fare system in Seoul allows a maximum of four transfers with no additional charges to encourage transit ridership. In order to analyze the transit transfers, this study developed quantitative indicators for public transportation evaluations differentiated from those of previous studies by the fact that it utilizes data mining techniques which incorporate massive amounts of data (over 10 million transits per day) derived from the smart card system. This study not only carried out an evaluation to improve public transportation quality but provided comparative analysis of the mobility handicapped and an evaluation of public transportation users’ regional equity. This evaluative analysis of Level of Services (LOS) for various items is expected to be adopted for analyzing LOS status and generating improvement priorities and to be utilized as an objective database for public transportation policy decisions
Genome-Based Construction of the Metabolic Pathways of Orientia tsutsugamushi and Comparative Analysis within the Rickettsiales Order
Orientia tsutsugamushi, the causative agent of
scrub typhus, is an obligate intracellular
bacterium that belongs to the order of
Rickettsiales. Recently, we have reported that
O. tsutsugamushi has a unique
genomic structure, consisting of highly
repetitive sequences, and suggested that it may
provide valuable insight into the evolution of
intracellular bacteria. Here, we have used
genomic information to construct the major
metabolic pathways of
O. tsutsugamushi and performed a
comparative analysis of the metabolic genes and
pathways of O. tsutsugamushi
with other members of the Rickettsiales order.
While O. tsutsugamushi has the
largest genome among the members of this order,
mainly due to the presence of repeated
sequences, its metabolic pathways have been
highly streamlined. Overall, the metabolic
pathways of O. tsutsugamushi
were similar to Rickettsia but
there were notable differences in several
pathways including carbohydrate metabolism, the
TCA cycle, and the synthesis of cell wall
components as well as in the transport systems.
Our results will provide a useful guide to the
postgenomic analysis of
O. tsutsugamushi and lead
to a better understanding of the virulence and
physiology of this intracellular pathogen
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