A missing operationalization: entrepreneurial competencies in multinational enterprise subsidiaries

We seek to provide a comprehensive operationalization of firm-specific variables that constitute multinational enterprise subsidiary entrepreneurial competencies. Towards this objective, we bring together notions from the fields of entrepreneurship and international business. Drawing on an empirical study of 260 subsidiaries located in the UK, we propose a comprehensive set of scales encompassing innovativeness, risk-taking, proactiveness, learning, intra-multinational networking, extra-multinational networking and autonomy; which capture distinct subsidiary entrepreneurial competencies at the subsidiary level. Research and managerial implications are discussed

Sustainability and scalability of university spinouts: A business model perspective

Most previous studies of university spinouts (USOs) have focused on what determines their formation from the perspectives of the entrepreneurs or of their parent universities. However, few studies have investigated how these entrepreneurial businesses actually grow and how their business models evolve in the process. This paper examines the evolution of USOs' business models over their different development phases. Using empirical evidence gathered from three comprehensive case studies, we explore how USOs' business models evolve over time, and the implications for the financial sustainability and operational scalability of these ventures. This paper extends existing research on the development of USOs, and highlights three themes for future research

Geological interpretation of volcanism and segmentation of the Mariana back-arc spreading center between 12.7°N and 18.3°N

The relationships between tectonic processes, magmatism, and hydrothermal venting along ∼600 km of the slow-spreading Mariana back-arc between 12.7°N and 18.3°N reveal a number of similarities and differences compared to slow-spreading mid-ocean ridges. Analysis of the volcanic geomorphology and structure highlights the complexity of the back-arc spreading center. Here, ridge segmentation is controlled by large-scale basement structures that appear to predate back-arc rifting. These structures also control the orientation of the chains of cross-arc volcanoes that characterize this region. Segment-scale faulting is oriented perpendicular to the spreading direction, allowing precise spreading directions to be determined. Four morphologically distinct segment types are identified: dominantly magmatic segments (Type I); magmatic segments currently undergoing tectonic extension (Type II); dominantly tectonic segments (Type III); and tectonic segments currently undergoing magmatic extension (Type IV). Variations in axial morphology (including eruption styles, neovolcanic eruption volumes, and faulting) reflect magma supply, which is locally enhanced by cross-arc volcanism associated with N-S compression along the 16.5°N and 17.0°N segments. In contrast, cross-arc seismicity is associated with N-S extension and increased faulting along the 14.5°N segment, with structures that are interpreted to be oceanic core complexes—the first with high-resolution bathymetry described in an active back-arc basin. Hydrothermal venting associated with recent magmatism has been discovered along all segment types

Choice of Structure, Business Model and Portfolio: Organizational Models of Knowledge Transfer Offices in British Universities

This paper addresses the gap in the knowledge transfer literature around how universities choose specific organizational models for their knowledge transfer offices (KTOs). Organization theory points towards strong interlinkages between strategy, structure and processes in organizations. This motivates an exploration of similar links within the organizational setup of KTOs. In doing so, the paper provides a unified theoretical framework around a university's choice of structure, business model and strategic preferences for their KTOs linked to university-specific contextual factors. A qualitative approach is used wherein four very distinct British universities are examined as individual case studies. The authors find that strategic aims of the university around practitioner engagement, the quantity of applied research and research specialization are key factors in determining the organizational characteristics of the KTO. The theoretical framework derived from the cases makes two key contributions to the university knowledge transfer literature. First, it links the university-level contextual factors to the local model of knowledge transfer. Second, it allows us to develop a set of generic models of knowledge transfer, which can potentially guide universities to develop their own specific models

Subduction erosion and basal friction along the sediment-starved convergent margin off Antofagasta, Chile

Subduction erosion is commonly associated with strong interplate coupling and a consequent abrasion of the upper plate. Northern Chile is an often cited example of a strongly coupled erosional margin. Its crystalline basement is inferred to form a strong upper plate, the trench axis contains little detectable sediment, and the subducting lower plate has a high‐relief horst‐graben topography. With little water‐rich sediment to reduce interplate friction, the high relief of an igneous ocean crust thrust beneath continental basement should generate high friction interplate abrasion. However, a prestack depth‐migrated seismic record images slope debris that collects in a frontal prism. This debris, including ∼30% pore fluid, fills subducting grabens and is subsequently incorporated into an ∼1.5‐km‐thick interplate reflective layer. The subduction zone thrust passes through the upper part of this layer. Interplate seismicity and taper analyses indicate basal friction at levels that are common in sedimented convergent margins. The continued growth of lower plate grabens after subduction probably accommodates upper plate material, a process that erodes the upper plate. Erosion is aided by weakening of the upper plate rock framework beneath the continental slope. This erosion undermines the upper plate and tips it seaward thereby steepening the continental slope which induces midslope gravity tectonics. Despite sediment starvation, a frontal prism constructed of remolded slope debris elevates pore pressure to reduce interplate friction. Coeval erosion and prism building control the size of the frontal prism. Processes other than high friction abrasion best explain subduction erosion along northern Chile

Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes

BACKGROUND: Data are lacking on the long-term effect on cardiovascular events of adding sitagliptin, a dipeptidyl peptidase 4 inhibitor, to usual care in patients with type 2 diabetes and cardiovascular disease. METHODS: In this randomized, double-blind study, we assigned 14,671 patients to add either sitagliptin or placebo to their existing therapy. Open-label use of antihyperglycemic therapy was encouraged as required, aimed at reaching individually appropriate glycemic targets in all patients. To determine whether sitagliptin was noninferior to placebo, we used a relative risk of 1.3 as the marginal upper boundary. The primary cardiovascular outcome was a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. RESULTS: During a median follow-up of 3.0 years, there was a small difference in glycated hemoglobin levels (least-squares mean difference for sitagliptin vs. placebo, -0.29 percentage points; 95% confidence interval [CI], -0.32 to -0.27). Overall, the primary outcome occurred in 839 patients in the sitagliptin group (11.4%; 4.06 per 100 person-years) and 851 patients in the placebo group (11.6%; 4.17 per 100 person-years). Sitagliptin was noninferior to placebo for the primary composite cardiovascular outcome (hazard ratio, 0.98; 95% CI, 0.88 to 1.09; P<0.001). Rates of hospitalization for heart failure did not differ between the two groups (hazard ratio, 1.00; 95% CI, 0.83 to 1.20; P = 0.98). There were no significant between-group differences in rates of acute pancreatitis (P = 0.07) or pancreatic cancer (P = 0.32). CONCLUSIONS: Among patients with type 2 diabetes and established cardiovascular disease, adding sitagliptin to usual care did not appear to increase the risk of major adverse cardiovascular events, hospitalization for heart failure, or other adverse events

Reality or Illusion? The Efficacy of Nonmarket Strategy in Institutional Risk Reduction

Nonmarket strategy researchers have postulated that political and social strategies reduce the exposure of firms to risk, but those arguments have received little empirical attention. In this paper, we integrate social capital and institutional theories to examine the efficacy of managerial political ties (MPT) and corporate social responsibility (CSR) in institutional risk reduction. Using survey data from 179 firms in Ghana, we find that whereas CSR reduces institutional risk exposure, MPT do not. We also find that the effect of MPT on risk exposure is moderated by public affairs functions. Contrary to extant literature, we do not find evidence of complementarity between MPT and CSR. Altogether, the findings do not only show that the proposed efficacy of MPT in risk reduction is illusive, but they also signal the need for scrutinizing the harmony between nonmarket political and social strategie