5,173 research outputs found
Towards Interactive Logic Programming
Linear logic programming uses provability as the basis for computation. In
the operational semantics based on provability, executing the
additive-conjunctive goal from a program simply terminates
with a success if both and are solvable from . This is an
unsatisfactory situation, as a central action of \& -- the action of choosing
either or by the user -- is missing in this semantics.
We propose to modify the operational semantics above to allow for more active
participation from the user. We illustrate our idea via muProlog, an extension
of Prolog with additive goals.Comment: 8 pages. It describes two execution models for interactive logic
programmin
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Cytochrome P450 endoplasmic reticulum-associated degradation (ERAD): therapeutic and pathophysiological implications.
The hepatic endoplasmic reticulum (ER)-anchored cytochromes P450 (P450s) are mixed-function oxidases engaged in the biotransformation of physiologically relevant endobiotics as well as of myriad xenobiotics of therapeutic and environmental relevance. P450 ER-content and hence function is regulated by their coordinated hemoprotein syntheses and proteolytic turnover. Such P450 proteolytic turnover occurs through a process known as ER-associated degradation (ERAD) that involves ubiquitin-dependent proteasomal degradation (UPD) and/or autophagic-lysosomal degradation (ALD). Herein, on the basis of available literature reports and our own recent findings of in vitro as well as in vivo experimental studies, we discuss the therapeutic and pathophysiological implications of altered P450 ERAD and its plausible clinical relevance. We specifically (i) describe the P450 ERAD-machinery and how it may be repurposed for the generation of antigenic P450 peptides involved in P450 autoantibody pathogenesis in drug-induced acute hypersensitivity reactions and liver injury, or viral hepatitis; (ii) discuss the relevance of accelerated or disrupted P450-ERAD to the pharmacological and/or toxicological effects of clinically relevant P450 drug substrates; and (iii) detail the pathophysiological consequences of disrupted P450 ERAD, contributing to non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) under certain synergistic cellular conditions
Cultural analysis of hero frames in American and North Korean media: focusing on tragedy and glorification
Title from PDF of title page (University of Missouri--Columbia, viewed on September 11, 2013).The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.Thesis advisor: Dr. Sandra DavidsonIncludes bibliographical references.M.A. University of Missouri--Columbia 2013.Dissertations, Academic -- University of Missouri--Columbia -- Journalism."May 2013"Both the U.S. media and The Rodong Sinmun, the state news website of North Korea, used hero frames to describe each other. The hero frame of the United States described itself as a hero, North Korea and Middle Eastern countries as villains, and the people of those countries and sometimes the United States as victims. Meanwhile, The Rodong Sinmun of North Korea used "hero" and "heroic" without a refined symbol system. In The Rodong Sinmun, Kim Il-Sung and Kim Jong-Il were the utmost heroes in that they enabled the heroic working class of North Korea to realize their historic importance and led North Korean soldiers in their success against imperialists. The hero frame used to describe Kim Il-Sung included metaphors such as an affectionate father, the sun, and a tiger. The hero frame for Kim Jong-Il used metaphors such as a mother, the sunshine, and a crane. Kim Il-Sung and Kim Jong-Il were perceived to be optimistic heroes who were not allowed in Korean traditional culture, as featured as the emotion of "han" and in the fable "Baby Commander.
An empirical analysis of the state of competition in OECD mobile wireless markets
Contra the current trend of deregulation, mobile wireless markets in the OECD member states appear, until recently, to have been more or less concentrated. The study estimates the equations for market concentration, mobile prices, and profits using annual panel data from 24 OECD member states for the 1998-2009 period, in order to assess their interaction. Mobile prices, measured by revenue per minute in constant USD PPP, are regarded as a direct measure of consumer welfare. Estimation results indicate that in the second half of the 2000s, market concentration had no effect on mobile prices, whereas the positive relationship between market concentration and profits persisted. In other words, the market-power hypothesis is rejected in the second half of the 2000s. This empirical result provides a strong case for a recent lenient approach towards regulation and merger attempts in OECD mobile wireless markets. Additionally, the study provides evidence that regulatory policies have affected mobile market structure and performance
Structure analysis of single- and multi-frequency subspace migrations in inverse scattering problems
In this literature, we carefully investigate the structure of single- and
multi-frequency imaging functions, that are usually employed in inverse
scattering problems. Based on patterns of the singular vectors of the
Multi-Static Response (MSR) matrix, we establish a relationship between imaging
functions and the Bessel function. This relationship indicates certain
properties of imaging functions and the reason behind enhancement in the
imaging performance by multiple frequencies. Several numerical simulations with
a large amount of noisy data are performed in order to support our
investigation.Comment: 11 pages, 10 figure
Online Appendix to: Peace through Cooperation or Peace through Strength? How to Achieve Peace in the Very Intractable Conflict Society
The Korean War, having started on June 25, 1950, has never formally ended. As the two Koreas are technically still at war, the conflict on the Korean Peninsula has become intractable. The goal of this study is to explore the attitudes of South Koreans living in the intractable conflict about how to achieve peace. To fulfill this goal, we conducted a nation-wide survey to investigate attitudes toward militant and cooperative internationalism. We also measured various variables involved with the intractable conflict. Our results indicate that the value of international harmony and equality as well as attitudes toward peace are the best predictors of cooperative internationalism, while the value of international harmony and equality as well as the attitudes toward war were the strongest predictors of militant internationalism. Our results also suggest that the tendency to regard inter-Korean relations as zero-sum relations and the attitudes toward peace mediated the relationship between international harmony and cooperative internationalism, while the zero-sum perception and attitudes toward war on the Korean Peninsula mediated the same value factor and the cooperative internationalism. Possible implications are discussed
Peace through Cooperation or Peace through Strength? How to Achieve Peace in the Very Intractable Conflict Society
The Korean War, having started on June 25, 1950, has never formally ended. As the two Koreas are technically still at war, the conflict on the Korean Peninsula has become intractable. The goal of this study is to explore the attitudes of South Koreans living in the intractable conflict about how to achieve peace. To fulfill this goal, we conducted a nation-wide survey to investigate attitudes toward militant and cooperative internationalism. We also measured various variables involved with the intractable conflict. Our results indicate that the value of international harmony and equality as well as attitudes toward peace are the best predictors of cooperative internationalism, while the value of international harmony and equality as well as the attitudes toward war were the strongest predictors of militant internationalism. Our results also suggest that the tendency to regard inter-Korean relations as zero-sum relations and the attitudes toward peace mediated the relationship between international harmony and cooperative internationalism, while the zero-sum perception and attitudes toward war on the Korean Peninsula mediated the same value factor and the cooperative internationalism. Possible implications are discussed
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