Comment je suis devenu linguiste

Philologue, linguiste et grammairien, Jean-Claude Chevalier est l’auteur d’une thèse de doctorat sur la Naissance de la notion de complément dans la grammaire française (Droz 1970). Il appartient à cette génération de philologues qui, à l’orée des années 1960, ont découvert la linguistique comme Moïse la Terre promise. Dans un entretien qu’il a bien voulu accorder à La Quinzaine littéraire, Jean-Claude Chevalier revient sur les étapes de son parcours et répond aux questions que pose l’irrupti..

Epidemiological profile of Echinococcosis in Morocco from 2014 to 2018: case of Tangier-Tetouan-Al Hoceima Region

In Morocco, the National Hydatidosis Control Program has approved considerable progress. However, updating epidemiological profile data of the disease is necessary. This study is carried out to explore the characteristics and epidemiological profile of Hydatidosis in Tangier-Tetouan-Al-Hoceima region. We conducted a retrospective descriptive study from 28 April 2019 to 18 February 2020. The data collected covering 2014-2018 period from the program reports. The statistical analysis was performed by EpiInfo 7. In total, 94 cases were notified. In 2015, we recorded the highest incidence (0.83 cases/100.000 inhabitants). The highest percentage of patients was in Tetouan (28,7%). 54.3% of cases were women and 57.4% were from rural areas. The age of 47,3% of the cases was [18-40[years. The association between the professional status and sex was statistically significant (p<0.05). 94.4% of cases, in the first stage of infection, were diagnosed by ultrasound. 84.7% presented hepatic localization. Almost all cases (98.9%) were treated surgically. In conclusion, the National Hydatidosis Control Program should direct the actions in rural areas where the living conditions of the population are precarious. The study of canine Hydatidosis will also be necessary in the context of environmental health to carry out an integrated control for the human Hydatidosis disease

Epidemiological profile of the imported Malaria in the north region of Morocco from 2014 to 2018

In Morocco, the epidemiological surveillance of imported Malaria still be the pillar of the eradication strategy of the disease as part of environmental health. The aim of this study is to describe the epidemiological profile of malaria in north region of Morocco. It is retrospective descriptive study, based on program reports, carried out from 28 April 2019 to 18 February 2020 covering 2014-2018 period. The statistical analysis is performed by Epiinfo 7. In total, 59 cases of imported Malaria were reported. Tangier-Assilah province presented the majority of the cases (62.7%). The frequency was highest in 2018 with 35,2% (19) of cases. The male patient (79.7%) and the age of] 15-30] years (50%) were the most detected. 55.5% of the cases had a Moroccan nationality and were travelling from Guinea (33.9%). Diagnosis was conducting less than 2 days in 75% since the onset of clinical signs. The parasite was Plasmodium falciparum for 84.7% of Malaria cases. In conclusion, to prevent the risk of re-emergence of the disease in the region, the prevention and control measures against the imported malaria can be established at the regional as well as national level to achieve the objective of the malaria eradication in Morocco

Study on antigenotoxic effects of Moroccan medicinal plants and spices using the white/white + somatic assay in Drosophila

The antigenotoxic action of a selection of medicinal plants and spices from Morocco including laurel (Laurus nobilis), rosemary ( Rosmarinus officinalis), verbena (Verbena triphylla), fenugreek (Trigonella foenum-graecum) and nutmeg (Myristica fragrens) was assessed using the eye white/white+ (w/w+) Somatic Mutation and Recombination Test (SMART) assay of Drosophila melanogaster. Methyl methanesulfonate (MMS) was used as a positive mutagenic compound inducing high frequencies of spots in Drosophila larvae. The frequencies of spots per eyes of a treated series are compared to those of its concurrent positive control series using &#967;2- test for evaluation of the antigenotoxic effect. The nutmeg at 1% (w/v) demonstrated a marked decrease in MMS-induced spots with an inhibition rate of 50%. Rosemary, fenugreek seeds and laurel showed different inhibition rates with different level of significance. African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(3) 2006: 22-3

Investigation of the mutagenic and antimutagenic effects of Origanum compactum essential oil and some of its constituents

In the present study, the chemical composition of Origanum compactum essential oil was determined by gas chromatography and mass spectrometry, and its mutagenic and antimutagenic activities were investigated by the somatic mutation and recombination test (SMART) in Drosophila melanogaster. No significant increase in the number of somatic mutations was observed with the essential oil tested using both the standard (ST) and high bio-activation (HB) cross. In order to investigate the antimutagenic effect of the essential oil, we have tested the effect on the indirect-acting mutagen urethane (URE), as well as the direct-acting mutagen methyl methanesulfonate (MMS). O. compactum essential oil showed a strong inhibitory effect against URE-induced mutagenicity, especially with the HB cross. However, only a weak inhibitory effect on the mutagenicity induced by MMS was observed. These results suggest that the detected antimutagenicity could be mediated by an inhibitory effect on metabolic activation. The essential oil was fractionated to identify the components responsible of the suppressing effect detected. Seven fractions were obtained: two of them showed the most potent inhibitory effect against URE-induced mutagenicity and were further fractionated. The sub-fractions obtained from the second chromatographic fractionation were tested for their antimutagenic activity, together with carvacrol and thymol. The highest antimutagenic effect obtained with the sub-fractions was similar to the effect of the crude essential oil, as well as to the effect of carvacrol alone. These results suggest the absence of a synergic antimutagenic effect between the components of O. compactum essential oil and indicate that carvacrol was the most active oil component. © 2007 Elsevier B.V. All rights reserved.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Investigation of the mutagenic and antimutagnic effects of Origanum compactum essential oil and some of its constituent

info:eu-repo/semantics/publishe