[LVIC-LIMSI]: Using Syntactic Features and Multi-polarity Words for Sentiment Analysis in Twitter

Abstract This paper presents the contribution of our team at task 2 of SemEval 2013: Sentiment Analysis in Twitter. We submitted a constrained run for each of the two subtasks. In the Contextual Polarity Disambiguation subtask, we use a sentiment lexicon approach combined with polarity shift detection and tree kernel based classifiers. In the Message Polarity Classification subtask, we focus on the influence of domain information on sentiment classification

Prostate Cancer in Renal Transplant Recipients: Results from a Large Contemporary Cohort

Objectives: The aim of this study was to assess the natural history of prostate cancer (PCa) in renal transplant recipients (RTRs) and to clarify the controversy over whether RTRs have a higher risk of PCa and poorer outcomes than non-RTRs, due to factors such as immunosuppression. Patients and Methods: We performed a retrospective multicenter study of RTRs diagnosed with cM0 PCa between 2001 and 2019. Primary outcomes were overall (OS) and cancer-specific survival (CSS). Secondary outcomes included biochemical recurrence and/or progression after active surveillance (AS) and evaluation of variables possibly influencing PCa aggressiveness and outcomes. Management modalities included surgery, radiation, cryotherapy, HIFU, AS, and watchful waiting. Results: We included 166 men from nine institutions. Median age and eGFR at diagnosis were 67 (IQR 60–73) and 45.9 mL/min (IQR 31.5–63.4). ASA score was >2 in 58.4% of cases. Median time from transplant to PCa diagnosis was 117 months (IQR 48–191.5), and median PSA at diagnosis was 6.5 ng/mL (IQR 5.02–10). The biopsy Gleason score was ≥8 in 12.8%; 11.6% and 6.1% patients had suspicion of ≥cT3 > cT2 and cN+ disease. The most frequent management method was radical prostatectomy (65.6%), followed by radiation therapy (16.9%) and AS (10.2%). At a median follow-up of 60.5 months (IQR 31–106) 22.9% of men (n = 38) died, with only n = 4 (2.4%) deaths due to PCa. Local and systemic progression rates were 4.2% and 3.0%. On univariable analysis, no major influence of immunosuppression type was noted, with the exception of a protective effect of antiproliferative agents (HR 0.39, 95% CI 0.16–0.97, p = 0.04) associated with a decreased risk of biochemical recurrence (BCR) or progression after AS. Conclusion: PCa diagnosed in RTRs is mainly of low to intermediate risk and organ-confined at diagnosis, with good cancer control and low PCa death at intermediate follow-up. RTRs have a non-negligible risk of death from causes other than PCa. Aggressive upfront management of the majority of RTRs with PCa may, therefore, be avoided

Race-free estimated glomerular filtration rate equation in kidney transplant recipients:development and validation study

OBJECTIVE: To compare the performance of a newly developed race-free kidney recipient specific glomerular filtration rate (GFR) equation with the three current main equations for measuring GFR in kidney transplant recipients.DESIGN: Development and validation study SETTING: 17 cohorts in Europe, the United States, and Australia (14 transplant centres, three clinical trials).PARTICIPANTS: 15 489 adults (3622 in development cohort (Necker, Saint Louis, and Toulouse hospitals, France), 11 867 in multiple external validation cohorts) who received kidney transplants between 1 January 2000 and 1 January 2021.MAIN OUTCOME MEASURE: The main outcome measure was GFR, measured according to local practice. Performance of the GFR equations was assessed using P 30 (proportion of estimated GFR (eGFR) within 30% of measured GFR (mGFR)) and correct classification (agreement between eGFR and mGFR according to GFR stages). The race-free equation, based on creatinine level, age, and sex, was developed using additive and multiplicative linear regressions, and its performance was compared with the three current main GFR equations: Modification of Diet in Renal Disease (MDRD) equation, Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) 2009 equation, and race-free CKD-EPI 2021 equation. RESULTS: The study included 15 489 participants, with 50 464 mGFR and eGFR values. The mean GFR was 53.18 mL/min/1.73m 2 (SD 17.23) in the development cohort and 55.90 mL/min/1.73m 2 (19.69) in the external validation cohorts. Among the current GFR equations, the race-free CKD-EPI 2021 equation showed the lowest performance compared with the MDRD and CKD-EPI 2009 equations. When race was included in the kidney recipient specific GFR equation, performance did not increase. The race-free kidney recipient specific GFR equation showed significantly improved performance compared with the race-free CKD-EPI 2021 equation and performed well in the external validation cohorts (P 30 ranging from 73.0% to 91.3%). The race-free kidney recipient specific GFR equation performed well in several subpopulations of kidney transplant recipients stratified by race (P 30 73.0-91.3%), sex (72.7-91.4%), age (70.3-92.0%), body mass index (64.5-100%), donor type (58.5-92.9%), donor age (68.3-94.3%), treatment (78.5-85.2%), creatinine level (72.8-91.3%), GFR measurement method (73.0-91.3%), and timing of GFR measurement post-transplant (72.9-95.5%). An online application was developed that estimates GFR based on recipient's creatinine level, age, and sex (https://transplant-prediction-system.shinyapps.io/eGFR_equation_KTX/). CONCLUSION: A new race-free kidney recipient specific GFR equation was developed and validated using multiple, large, international cohorts of kidney transplant recipients. The equation showed high accuracy and outperformed the race-free CKD-EPI 2021 equation that was developed in individuals with native kidneys.TRIAL REGISTRATION: ClinicalTrials.gov NCT05229939.</p

Quality Indicators for Colonoscopy Procedures: A Prospective Multicentre Method for Endoscopy Units

BACKGROUND AND AIMS: Healthcare professionals are required to conduct quality control of endoscopy procedures, and yet there is no standardised method for assessing quality. The topic of the present study was to validate the applicability of the procedure in daily practice, giving physicians the ability to define areas for continuous quality improvement. METHODS: In ten endoscopy units in France, 200 patients per centre undergoing colonoscopy were enrolled in the study. An evaluation was carried out based on a prospectively developed checklist of 10 quality-control indicators including five dependent upon and five independent of the colonoscopy procedure. RESULTS: Of the 2000 procedures, 30% were done at general hospitals, 20% at university hospitals, and 50% in private practices. The colonoscopies were carried out for a valid indication for 95.9% (range 92.5-100). Colon preparation was insufficient in 3.7% (range 1-10.5). Colonoscopies were successful in 95.3% (range 81-99). Adenoma detection rate was 0.31 (range 0.17-0.45) in successful colonoscopies. CONCLUSION: This tool for evaluating the quality of colonoscopy procedures in healthcare units is based on standard endoscopy and patient criteria. It is an easy and feasible procedure giving the ability to detect suboptimal practice and differences between endoscopy-units. It will enable individual units to assess the quality of their colonoscopy techniques

CEA LIST: Processing low-resource languages for CoNLL 2018

International audienceIn this paper, we describe the system used for our first participation at the CoNLL 2018 shared task. The submitted system largely reused the state of the art parser from CoNLL 2017 (https://github.com/tdozat/Parser-v2). We enhanced this system for morphological features predictions, and we used all available resources to provide accurate models for low-resource languages. We ranked 5th of 27 participants in MLAS for building morphology aware dependency trees, 2nd for morphological features only, and 3rd for tagging (UPOS) and parsing (LAS) low-resource languages

Effects of Melting Layer in Airborne Meteorological X-Band Radar Observations

International audienceMost civil aviation aircraft are equipped with meteorological radar working at the X-band (f≈10GHz; λ≈3.2cm). These radars use a small antenna and, thus, a large beamwidth, around 3°-4°, for observations over long distances (up to 350km). In the presence of microphysical inhomogeneities inside a radar sampling volume, as filling by different hydrometeor categories, radar reflectivity measurements are biased. An important bias occurs when a radar cell is cut by a nonresolved layer of melting snowflakes whose attenuation is high compared to those of rain and dry snow. This paper illustrates the effects in precipitation-attenuation correction schemes (PACS) of the inhomogeneity associated with the 0°C isotherm. It proposes a method to take into account these effects in PACS. Adaptation of the method to other frequency bands and ground-based radar observations is easy

Effects of Melting Layer in Airborne Meteorological X-Band Radar Observations

International audienceMost civil aviation aircraft are equipped with meteorological radar working at the X-band (f≈10GHz; λ≈3.2cm). These radars use a small antenna and, thus, a large beamwidth, around 3°-4°, for observations over long distances (up to 350km). In the presence of microphysical inhomogeneities inside a radar sampling volume, as filling by different hydrometeor categories, radar reflectivity measurements are biased. An important bias occurs when a radar cell is cut by a nonresolved layer of melting snowflakes whose attenuation is high compared to those of rain and dry snow. This paper illustrates the effects in precipitation-attenuation correction schemes (PACS) of the inhomogeneity associated with the 0°C isotherm. It proposes a method to take into account these effects in PACS. Adaptation of the method to other frequency bands and ground-based radar observations is easy

FlowX: Quantum

&lt;p&gt;Quantum computing framework for computational fluid dynamics applications.&lt;/p&gt