123 research outputs found

    Optimal Fully Electric Vehicle load balancing with an ADMM algorithm in Smartgrids

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    In this paper we present a system architecture and a suitable control methodology for the load balancing of Fully Electric Vehicles at Charging Station (CS). Within the proposed architecture, control methodologies allow to adapt Distributed Energy Resources (DER) generation profiles and active loads to ensure economic benefits to each actor. The key aspect is the organization in two levels of control: at local level a Load Area Controller (LAC) optimally calculates the FEVs charging sessions, while at higher level a Macro Load Area Aggregator (MLAA) provides DER with energy production profiles, and LACs with energy withdrawal profiles. Proposed control methodologies involve the solution of a Walrasian market equilibrium and the design of a distributed algorithm.Comment: This paper has been accepted for the 21st Mediterranean Conference on Control and Automation, therefore it is subjected to IEEE Copyrights. See IEEE copyright notice at http://www.ieee.org/documents/ieeecopyrightform.pd

    Closed-Form Approximation of Timer Option Prices under General Stochastic Volatility Models

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    We develop an asymptotic expansion technique for pricing timer options under general stochastic volatility models around small volatility of variance. Closed-form approximation formulas have been obtained for the Heston model and the 3/2-model. The approximation has an easy-to-understand Black-Scholes-like form and many other attractive properties. Numerical analysis shows that the approximation formulas are very fast and accurate

    Closed-Form Approximation of Timer Option Prices under General Stochastic Volatility Models

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    We develop an asymptotic expansion technique for pricing timer options under general stochastic volatility models around small volatility of variance. Closed-form approximation formulas have been obtained for the Heston model and the 3/2-model. The approximation has an easy-to-understand Black-Scholes-like form and many other attractive properties. Numerical analysis shows that the approximation formulas are very fast and accurate

    Freight consolidation through carrier collaboration:A cooperative game

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    Reducing inefficient truck movements, this research investigates the potential of freight consolidation through carrier collaboration. Considering the financial benefits of consolidation as well as the additional cost arising from collaboration, we introduce a cooperative game in which several carriers can collaborate by pooling transportation capacities. Although the core of this game can be empty, we provide three conditions under which core non-emptiness is preserved. Numerical experiments indicate, moreover, that core non-emptiness is also likely outside these conditions

    Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120V3 signatures in the regulation of Co-Receptor usage

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    <p>Abstract</p> <p>Background</p> <p>The third variable loop (V3) of the HIV-1 gp120 surface protein is a major determinant of cellular co-receptor binding. However, HIV-1 can also modulate its tropism through other regions in gp120, such as V1, V2 and C4 regions, as well as in the gp41 protein. Moreover, specific changes in gp41 are likely to be responsible for of damage in gp120-CCR5 interactions, resulting in potential resistance to CCR5 inhibitors.</p> <p>In order to genetically characterize the two envelope viral proteins in terms of co-receptor usage, we have analyzed 526 full-length <it>env </it>sequences derived from HIV-1 subtype-B infected individuals, from our and public (Los Alamos) databases. The co-receptor usage was predicted by the analysis of V3 sequences using Geno2Pheno (G2P) algorithm. The binomial correlation phi coefficient was used to assess covariation among gp120<sub>V3 </sub>and gp41 mutations; subsequently the average linkage hierarchical agglomerative clustering was performed.</p> <p>Results</p> <p>According to G2P false positive rate (FPR) values, among 526 env-sequences analyzed, we further characterized 196 sequences: 105 with FPR <5% and 91 with FPR >70%, for X4-using and R5-using viruses, respectively.</p> <p>Beyond the classical signatures at 11/25 V3 positions (S11S and E25D, R5-tropic viruses; S11KR and E25KRQ, X4-tropic viruses), other specific V3 and gp41 mutations were found statistically associated with the co-receptor usage. Almost all of these specific gp41 positions are exposed on the surface of the glycoprotein. By the covariation analysis, we found several statistically significant associations between V3 and gp41 mutations, especially in the context of CXCR4 viruses. The topology of the dendrogram showed the existence of a cluster associated with R5-usage involving E25D<sub>V3</sub>, S11S<sub>V3</sub>, T22A<sub>V3</sub>, S129DQ<sub>gp41 </sub>and A96N<sub>gp41 </sub>signatures (bootstrap = 0.88). Conversely, a large cluster was found associated with X4-usage involving T8I<sub>V3</sub>, S11KR<sub>V3</sub>, F20IVY<sub>V3</sub>, G24EKR<sub>V3</sub>, E25KR<sub>V3</sub>, Q32KR<sub>V3</sub>, A30T<sub>gp41</sub>, A189S<sub>gp41</sub>, N195K<sub>gp41 </sub>and L210P<sub>gp41 </sub>mutations (bootstrap = 0.84).</p> <p>Conclusions</p> <p>Our results show that gp120<sub>V3 </sub>and several specific amino acid changes in gp41 are associated together with CXCR4 and/or CCR5 usage. These findings implement previous observations that determinants of tropism may reside outside the V3-loop, even in the gp41. Further studies will be needed to confirm the degree to which these gp41 mutations contribute directly to co-receptor use.</p

    Bilateral photon emission from a vibrating mirror and multiphoton entanglement generation

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    Entanglement plays a crucial role in the development of quantum-enabled devices. One significant objective is the deterministic creation and distribution of entangled states, achieved, for example, through a mechanical oscillator interacting with confined electromagnetic fields. In this study, we explore a cavity resonator containing a two-sided perfect mirror. Although the mirror separates the cavity modes into two independent confined electromagnetic fields, the radiation pressure interaction gives rise to high-order effective interactions across all subsystems. Depending on the chosen resonant conditions, which are also related to the position of the mirror, we study 2n2n-photon entanglement generation and bilateral photon pair emission. Demonstrating the non-classical nature of the mechanical oscillator, we provide a pathway to control these phenomena, opening potential applications in quantum technologies. Looking ahead, similar integrated devices could be used to entangle subsystems across vastly different energy scales, such as microwave and optical photons

    Time-weighted lactate as a predictor of adverse outcome in acute heart failure

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    The role of dynamic changes in lactate concentrations on prognosis in acute heart failure has been poorly investigated. The aim of this study was to explore the predictive value of 24 h time-weighted lactate (LACTW ) in patients with acute heart failure
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