Estudo das argamassas antigas da igreja de n. sA do Amparo dos homens pardos em São Cristóvão SE/BR/ Study of the ancient mortars of the church of n. Sheels of mold men in Saint Christmas SE / BR

Na conservação e restauro das categorias patrimoniais e, em específico, do patrimônio cultural material, os tratamentos técnicos das degradações que ocorrem nos objetos portadores de juízo de valor histórico e estético ensejam a busca dos conhecimentos construtivos do passado e do presente. Este artigo relata pesquisa de Iniciação Científica realizada na Universidade Federal de Sergipe no Departamento de Arquitetura e Urbanismo entre agosto de 2017 e julho de 2018, na área de materiais, que analisou e caracterizou as argamassas da Igreja de N. Sa do Amparo dos Homens Pardos construída em meados do século XVIII na Cidade de São Cristóvão, interior do Estado de Sergipe. O objetivo geral é conhecer a produção de argamassas antigas e buscar alternativas para “curar” patologias relacionadas a fenômenos como umidades, cristalizações, “leprosidades” e outros agentes aos quais os objetos patrimoniais estão suscetíveis. Portanto, revelam-se técnicas antigas muito conhecidas da produção de argamassas de “saneamento” restaurador, demonstram-se propriedades e características das argamassas de restauro e suas composições (areia, cal, saibro, argilas, sais, cinza de carvão, etc.), e se ocorreu a associação do pó cerâmico, de escória de aciaria, de resíduos vegetais ou animais (sangue, gordura, sementes, cinzas, óleos, etc.) encontrando no parâmetro de respeito ao passado e de seu conhecimento, um agir no presente e no futuro. O estudo é constituído por pesquisas históricas sobre a cidade de São Cristóvão e edificação, acrescida de experimentos laboratoriais a partir de coleta de amostras nesta Igreja, resultando em dados que permitem a determinação das características das argamassas de reboco/emboço deste patrimônio, inventário sobre a caracterização de argamassas e técnicas construtivas antigas nas edificações históricas do Estado de Sergipe, assim como fontes de dados gerais para outras pesquisas que venham a ser desenvolvidas na área da Tecnologia da Preservação e Restauro

MANIFESTAÇÕES ESTOMATOGNÁTICAS DE PACIENTES INFECTADOS PELO VÍRUS DA IMUNODEFICIÊNCIA HUMANA HIV/AIDS EM ÂMBITO HOSPITALAR: REVISÃO INTEGRATIVA DA LITERATURA

This article is a literature review that addresses a study of high relevance for dental care in patients with systemic impairment as a consequence of HIV, with a focus on hospital management. Human Immunodeficiency Virus (HIV) infection is a condition that affects 39 million people worldwide, presenting consequences in several areas and multifactorial circumstances in the human body, such as the pandemic, where there was a significant increase in deaths among HIV-positive people, including when the virus is associated with other opportunistic diseases, around 40.4 million deaths in the period 2020-2022 were from diseases associated with AIDS during the pandemic. The stomatognathic manifestations of HIV are significant in interfering with the patient's quality of life, and can react to medications, exacerbate autoimmune diseases, accentuate signs and symptoms of opportunistic infections, worsen oral ulcers that arise as a result of oncological treatment and changes in patients with other underlying diseases undergoing hospital treatment. The objective of this article is to provide an updated view of the patient as a whole and stomatognathic manifestations, in addition to highlighting the importance of early diagnosis through clinical evaluation of the oral cavity and adjacent structures, providing valuable information for health professionals, researchers and managers. hospitals, contributing to a more effective and compassionate approach to the care of HIV-positive patients with stomatognathic manifestations. Knowledge of these manifestations and their appropriate treatment, in addition to adding to the patient's well-being, is also capable of assisting in diagnosis and reducing morbidity associated with HIV.Este artigo é uma revisão de literatura que aborda um estudo de alta relevância para o atendimento odontológico em pacientes com comprometimento sistêmico como consequência do HIV, com enfoque no manejo hospitalar. A infecção pelo Vírus da Imunodeficiência Humana (HIV) é uma condição que afeta 39 milhões de pessoas no mundo, apresentando consequências em diversas áreas e circunstâncias multifatoriais  no corpo humano, como exemplo  a pandemia, onde  houve um aumento significativo de óbitos entre soropositivos, inclusive quando o vírus está associado a demais doenças oportunistas, cerca de 40,4 milhões de óbitos no período de 2020-2022 foram de doenças associadas a AIDS durante a pandemia. As manifestações estomatognáticas do HIV são significativas para interferir na qualidade de vida do paciente, podendo reagir a medicamentos, exacerbar doenças autoimunes, acentuar sinais e sintomas de infecções oportunistas, agregar piora nas úlceras orais que surgem com decorrência do tratamento oncológico e alterações em pacientes com outras doenças de base em tratamento hospitalar. O objetivo deste artigo é fornecer uma visão atualizada do paciente como um todo e das manifestações estomatognáticas, além de destacar a importância do diagnóstico precoce através da avaliação clínica da cavidade oral e estruturas adjacentes, através de informações valiosas para profissionais de saúde, pesquisadores e gestores hospitalares, contribuindo para uma abordagem mais eficaz e compassiva no cuidado de pacientes soropositivos com manifestações estomatognáticas. O conhecimento dessas manifestações e seu tratamento adequado além de agregar ao bem-estar do paciente é igualmente capaz de auxiliar no diagnóstico e reduzir a morbidade associada ao HIV

Epidemiology of Disappearing Plasmodium vivax Malaria: A Case Study in Rural Amazonia

Background: New frontier settlements across the Amazon Basin pose a major challenge for malaria elimination in Brazil. Here we describe the epidemiology of malaria during the early phases of occupation of farming settlements in Remansinho area, Brazilian Amazonia. We examine the relative contribution of low-density and asymptomatic parasitemias to the overall Plasmodium vivax burden over a period of declining transmission and discuss potential hurdles for malaria elimination in Remansinho and similar settings. Methods: Eight community-wide cross-sectional surveys, involving 584 subjects, were carried out in Remansinho over 3 years and complemented by active and passive surveillance of febrile illnesses between the surveys. We used quantitative PCR to detect low-density asexual parasitemias and gametocytemias missed by conventional microscopy. Mixed-effects multiple logistic regression models were used to characterize independent risk factors for P. vivax infection and disease. Principal Findings/Conclusions P. vivax prevalence decreased from 23.8% (March–April 2010) to 3.0% (April–May 2013), with no P. falciparum infections diagnosed after March–April 2011. Although migrants from malaria-free areas were at increased risk of malaria, their odds of having P. vivax infection and disease decreased by 2–3% with each year of residence in Amazonia. Several findings indicate that low-density and asymptomatic P. vivax parasitemias may complicate residual malaria elimination in Remansinho: (a) the proportion of subpatent infections (i.e. missed by microscopy) increased from 43.8% to 73.1% as P. vivax transmission declined; (b) most (56.6%) P. vivax infections were asymptomatic and 32.8% of them were both subpatent and asymptomatic; (c) asymptomatic parasite carriers accounted for 54.4% of the total P. vivax biomass in the host population; (d) over 90% subpatent and asymptomatic P. vivax had PCR-detectable gametocytemias; and (e) few (17.0%) asymptomatic and subpatent P. vivax infections that were left untreated progressed to clinical disease over 6 weeks of follow-up and became detectable by routine malaria surveillance

The histology of ovarian cancer: worldwide distribution and implications for international survival comparisons (CONCORD-2)

Objective Ovarian cancers comprise several histologically distinct tumour groups with widely different prognosis. We aimed to describe the worldwide distribution of ovarian cancer histology and to understand what role this may play in international variation in survival. Methods The CONCORD programme is the largest population-based study of global trends in cancer survival. Data on 681,759 women diagnosed during 1995â\u80\u932009 with cancer of the ovary, fallopian tube, peritoneum and retroperitonum in 51 countries were included. We categorised ovarian tumours into six histological groups, and explored the worldwide distribution of histology. Results During 2005â\u80\u932009, type II epithelial tumours were the most common. The proportion was much higher in Oceania (73.1%), North America (73.0%) and Europe (72.6%) than in Central and South America (65.7%) and Asia (56.1%). By contrast, type I epithelial tumours were more common in Asia (32.5%), compared with only 19.4% in North America. From 1995 to 2009, the proportion of type II epithelial tumours increased from 68.6% to 71.1%, while the proportion of type I epithelial tumours fell from 23.8% to 21.2%. The proportions of germ cell tumours, sex cord-stromal tumours, other specific non-epithelial tumours and tumours of non-specific morphology all remained stable over time. Conclusions The distribution of ovarian cancer histology varies widely worldwide. Type I epithelial, germ cell and sex cord-stromal tumours are generally associated with higher survival than type II tumours, so the proportion of these tumours may influence survival estimates for all ovarian cancers combined. The distribution of histological groups should be considered when comparing survival between countries and regions

Lancet

BACKGROUND: In 2015, the second cycle of the CONCORD programme established global surveillance of cancer survival as a metric of the effectiveness of health systems and to inform global policy on cancer control. CONCORD-3 updates the worldwide surveillance of cancer survival to 2014. METHODS: CONCORD-3 includes individual records for 37.5 million patients diagnosed with cancer during the 15-year period 2000-14. Data were provided by 322 population-based cancer registries in 71 countries and territories, 47 of which provided data with 100% population coverage. The study includes 18 cancers or groups of cancers: oesophagus, stomach, colon, rectum, liver, pancreas, lung, breast (women), cervix, ovary, prostate, and melanoma of the skin in adults, and brain tumours, leukaemias, and lymphomas in both adults and children. Standardised quality control procedures were applied; errors were rectified by the registry concerned. We estimated 5-year net survival. Estimates were age-standardised with the International Cancer Survival Standard weights. FINDINGS: For most cancers, 5-year net survival remains among the highest in the world in the USA and Canada, in Australia and New Zealand, and in Finland, Iceland, Norway, and Sweden. For many cancers, Denmark is closing the survival gap with the other Nordic countries. Survival trends are generally increasing, even for some of the more lethal cancers: in some countries, survival has increased by up to 5% for cancers of the liver, pancreas, and lung. For women diagnosed during 2010-14, 5-year survival for breast cancer is now 89.5% in Australia and 90.2% in the USA, but international differences remain very wide, with levels as low as 66.1% in India. For gastrointestinal cancers, the highest levels of 5-year survival are seen in southeast Asia: in South Korea for cancers of the stomach (68.9%), colon (71.8%), and rectum (71.1%); in Japan for oesophageal cancer (36.0%); and in Taiwan for liver cancer (27.9%). By contrast, in the same world region, survival is generally lower than elsewhere for melanoma of the skin (59.9% in South Korea, 52.1% in Taiwan, and 49.6% in China), and for both lymphoid malignancies (52.5%, 50.5%, and 38.3%) and myeloid malignancies (45.9%, 33.4%, and 24.8%). For children diagnosed during 2010-14, 5-year survival for acute lymphoblastic leukaemia ranged from 49.8% in Ecuador to 95.2% in Finland. 5-year survival from brain tumours in children is higher than for adults but the global range is very wide (from 28.9% in Brazil to nearly 80% in Sweden and Denmark). INTERPRETATION: The CONCORD programme enables timely comparisons of the overall effectiveness of health systems in providing care for 18 cancers that collectively represent 75% of all cancers diagnosed worldwide every year. It contributes to the evidence base for global policy on cancer control. Since 2017, the Organisation for Economic Co-operation and Development has used findings from the CONCORD programme as the official benchmark of cancer survival, among their indicators of the quality of health care in 48 countries worldwide. Governments must recognise population-based cancer registries as key policy tools that can be used to evaluate both the impact of cancer prevention strategies and the effectiveness of health systems for all patients diagnosed with cancer. FUNDING: American Cancer Society; Centers for Disease Control and Prevention; Swiss Re; Swiss Cancer Research foundation; Swiss Cancer League; Institut National du Cancer; La Ligue Contre le Cancer; Rossy Family Foundation; US National Cancer Institute; and the Susan G Komen Foundation

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Development and validation of HERWIG 7 tunes from CMS underlying-event measurements

This paper presents new sets of parameters (“tunes”) for the underlying-event model of the HERWIG7 event generator. These parameters control the description of multiple-parton interactions (MPI) and colour reconnection in HERWIG7, and are obtained from a fit to minimum-bias data collected by the CMS experiment at s=0.9, 7, and 13Te. The tunes are based on the NNPDF 3.1 next-to-next-to-leading-order parton distribution function (PDF) set for the parton shower, and either a leading-order or next-to-next-to-leading-order PDF set for the simulation of MPI and the beam remnants. Predictions utilizing the tunes are produced for event shape observables in electron-positron collisions, and for minimum-bias, inclusive jet, top quark pair, and Z and W boson events in proton-proton collisions, and are compared with data. Each of the new tunes describes the data at a reasonable level, and the tunes using a leading-order PDF for the simulation of MPI provide the best description of the dat

Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV

Peer reviewe

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe