Fabrication of titanium multi-wall Thermal Protection System (TPS) test panel arrays

Several arrays were designed and tested. Tests included vibrational and acoustical tests, radiant heating tests, and thermal conductivity tests. A feasible manufacturing technique was established for producing the protection system panels

Re-design and fabrication of titanium multi-wall Thermal Protection System (TPS) test panels

The Titanium Multi-wall Thermal Protection System (TIPS) panel was re-designed to incorporate Ti-6-2-4-2 outer sheets for the hot surface, ninety degree side closures for ease of construction and through panel fastness for ease of panel removal. Thermal and structural tests were performed to verify the design. Twenty-five panels were fabricated and delivered to NASA for evaluation at Langley Research Center and Johnson Space Center

Corticosteroid vs Platelet Rich Plasma Injections in the Treatment of Chronic Plantar Fasciitis

Objective: To assess the effectiveness of platelet rich plasma (PRP) injections in the treatment of chronic plantar fasciitis compared to traditional corticosteroid injections. Design: Systematic literature review. Methods: A literature search was performed in Pubmed using the search terms “plantar fasciitis” and “platelet rich plasma”. Inclusion criteria included publication within 10 years, randomized control trial, human study, and containing the American Orthopedic Foot and Ankle Society (AOFAS) hindfoot scoring system. Results: Our literature search resulted in the review of three randomized- control trials. Mahindra et al. showed that PRP was superior to corticosteroid injections in the treatment of chronic plantar fasciitis at 3 months. Acosto-Olivo et al. found both treatments were equally effective at reducing symptoms of plantar fasciitis over a 16- week period. Similar to Mahindra et al., Monto found that PRP was a more effective treatment for maintaining remission of chronic plantar fasciitis over a 24- month period. Conclusion: PRP injections are shown to be as effective or more effective than corticosteroid injections in the treatment of chronic plantar fasciitis that has failed conservative treatment

Fabrication of prepackaged superalloy honeycomb Thermal Protection System (TPS) panels

High temperature materials were surveyed, and Inconel 617 and titanium were selected for application to a honeycomb TPS configuration designed to withstand 2000 F. The configuration was analyzed both thermally and structurally. Component and full-sized panels were fabricated and tested to obtain data for comparison with analysis. Results verified the panel design. Twenty five panels were delivered to NASA Langley Research Center for additional evaluation

Design and fabrication of titanium multi-wall Thermal Protection System (TPS) test panels

A titanium multiwall thermal protection system panel was designed. The panel is a nine sheet sandwich structure consisting of an upper and lower face sheet; four dimpled sheets, three septum sheets, and clips for attachment to a vehicle structure. An acceptable fabrication process was developed, and the panel design was verified through mechanical and thermal testing of component specimens. A design was completed which takes into consideration fabrication techniques, thermal properties, mechanical properties, and materials availability

Effect of omitting post-milking teat disinfection on the mastitis infection rate of dairy cows over a full lactation

Abstract Fifty-six autumn calving Holstein-Friesian dairy cows were milked as one herd over a complete lactation. Right-sided teats were disinfected post-milking by submersing teats in a chlorohexadine solution, while teat disinfectant was omitted on left-sided teats. Milk samples were taken from individual quarters to measure SCC on thirteen occasions during the lactation. Mean somatic cell count was lower (P<0.01) in milk from disinfected compared to non-disinfected quarters over the full lactation. The number of clinical infections was also significantly lower (P<0.001) in disinfected compared to nondisinfected quarters. Omitting teat disinfection also resulted in a higher (P<0.01) number of non-haemolytic staphylococci and Staphylococcus aureus pathogens in those quarters compared to disinfected quarters

Fibromuscular Arterial Disease

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75604/1/j.1440-1673.1970.tb01633.x.pd

Prenatal maternal depression alters amygdala functional connectivity in 6-month-old infants

10.1038/tp.2015.3Translational Psychiatry52GUSTO (Growing up towards Healthy Outcomes

A long term self-managed handwriting intervention for people with Parkinson’s: Results from the control group of a phase II randomised controlled trial

Objective: To report on the control group of a trial primarily designed to investigate exercise for improving mobility in people with Parkinson’s Disease (pwP). The control group undertook a handwriting intervention to control for attention and time spent practising a specific activity. Design: Secondary analysis of a two arm parallel phase II randomised controlled trial with blind assessment. Setting: Community Participants: PwP able to walk ≥100meters and with no contraindication to exercise recruited from the Thames valley, UK and randomised (1:1) to exercise or handwriting, via a concealed computer-generated list. Intervention: Handwriting was undertaken at home and exercise in community facilities, both were delivered through workbooks with monthly support visits and involved practice for one hour, twice weekly, over six months. Main measures: Handwriting was assessed, at baseline, 3, 6 and 12months, using a pangram giving writing speed, amplitude (area) and progressive reduction in amplitude (ratio). The MSD-UPDRS item 2.7 (UPDRS-2.7) measured self-reported handwriting deficits. Results: 105 pwP were recruited (analysed: n=51 handwriting, n=54 exercise). Forty pwP adhered to the handwriting program most completing ≥1 session/week. Moderate effects were found for amplitude (total area: d=0.32 95%CI -0.11:0.7, p=0.13) in favour of handwriting over 12months, effects for writing speed and ratio parameters were small ≤0.11. Self-reported handwriting difficulties also favoured handwriting (UPDRS-2.7: OR= 0.55 95%CI 0.34:0.91, p=0.02). No adverse effects were reported Conclusion PwP generally adhere to self-directed home handwriting which may provide benefit with minimal risk. Encouraging effects were found in writing amplitude and, moreover, perceived ability. (ClinicalTrials.Gov:NCT01439022)