1,392 research outputs found
Parvovirus B19 infection in pediatric transplant patients
Evidence of recent parvovirus virus infection (as determined by the presence of a positive IgM antibody titer) without other identified causes of anemia was found in 5 of 26 pediatric solid-organ transplant recipients evaluated for moderate-to-severe anemia between June 1990 and July 1991. Anemia tended to be chronic (median duration of anemia at the time of diagnosis was 12 weeks) and was associated with normal red blood cell indices in the absence of reticulocytes. The median age of the children at the time of presentation with anemia due to parvovirus was 1.8 years at a median time of 8 months after transplantation. Four of the 5 children were treated with i.v. immunoglobulin because of persistance of anemia requiring blood transfusions. A response characterized by an increase in reticulocyte count and normalization of hemoglobin was seen in each of these patients 2-4 weeks after treatment. The remaining patient experienced a spontaneous recovery from her anemia. Parvovirus infection should be included in the differential diagnosis of solid-organ transplant recipients presenting with severe anemia associated with low or absent reticulocytes
Light-cone gauge Hamiltonian for AdS_4 x CP^3 superstring
It is developed the phase-space formulation for the Type IIA superstring on
the AdS_4 x CP^3 background in the kappa-symmetry light-cone gauge for which
the light-like directions are taken from the D=3 Minkowski boundary of AdS_4.
After fixing bosonic light-cone gauge the superstring Hamiltonian is expressed
as a function of the transverse physical variables and in the quadratic
approximation corresponds to the light-cone gauge-fixed IIA superstring in flat
space.Comment: 12 pages, LaTeX; v2 minor improvements of the text, misprints
corrected, reference added; v3: missing terms in Eqs.(8),(53) and (56) adde
Alpha oscillatory activity during attentional control in children with Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), and ASD+ADHD
BACKGROUND:
Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) share impairments in top-down and bottom-up modulation of attention. However, it is not yet well understood if co-occurrence of ASD and ADHD reflects a distinct or additive profile of attention deficits. We aimed to characterise alpha oscillatory activity (stimulus-locked alpha desynchronisation and prestimulus alpha) as an index of integration of top-down and bottom-up attentional processes in ASD and ADHD.
METHODS:
Children with ASD, ADHD, comorbid ASD+ADHD, and typically-developing children completed a fixed-choice reaction-time task (‘Fast task’) while neurophysiological activity was recorded. Outcome measures were derived from source-decomposed neurophysiological data. Main measures of interest were prestimulus alpha power and alpha desynchronisation (difference between poststimulus and prestimulus alpha). Poststimulus activity linked to attention allocation (P1, P3), attentional control (N2), and cognitive control (theta synchronisation, 100–600 ms) was also examined. ANOVA was used to test differences across diagnostics groups on these measures. Spearman’s correlations were used to investigate the relationship between attentional control processes (alpha oscillations), central executive functions (theta synchronisation), early visual processing (P1), and behavioural performance.
RESULTS:
Children with ADHD (ADHD and ASD+ADHD) showed attenuated alpha desynchronisation, indicating poor integration of top-down and bottom-up attentional processes. Children with ADHD showed reduced N2 and P3 amplitudes, while children with ASD (ASD and ASD+ADHD) showed greater N2 amplitude, indicating atypical attentional control and attention allocation across ASD and ADHD. In the ASD group, prestimulus alpha and theta synchronisation were negatively correlated, and alpha desynchronisation and theta synchronisation were positively correlated, suggesting an atypical association between attentional control processes and executive functions.
CONCLUSIONS:
ASD and ADHD are associated with disorder-specific impairments, while children with ASD+ADHD overall presented an additive profile with attentional deficits of both disorders. Importantly, these findings may inform the improvement of transdiagnostic procedures and optimisation of personalised intervention approaches
Two-loop Integrability of Planar N=6 Superconformal Chern-Simons Theory
Bethe ansatz equations have been proposed for the asymptotic spectral problem
of AdS_4/CFT_3. This proposal assumes integrability, but the previous
verification of weak-coupling integrability covered only the su(4) sector of
the ABJM gauge theory. Here we derive the complete planar two-loop dilatation
generator of N=6 superconformal Chern-Simons theory from osp(6|4)
superconformal symmetry. For the osp(4|2) sector, we prove integrability
through a Yangian construction. We argue that integrability extends to the full
planar two-loop dilatation generator, confirming the applicability of the Bethe
equations at weak coupling. Further confirmation follows from an analytic
computation of the two-loop twist-one spectrum.Comment: 45 pages, v2: typos in (D.9) fixed, reference added, many small
change
Spelling in adolescents with dyslexia: errors and modes of assessment
In this study we focused on the spelling of high-functioning students with dyslexia. We made a detailed classification of the errors in a word and sentence dictation task made by 100 students with dyslexia and 100 matched control students. All participants were in the first year of their bachelor’s studies and had Dutch as mother tongue. Three main error categories were distinguished: phonological, orthographic, and grammatical errors (on the basis of morphology and language-specific spelling rules). The results indicated that higher-education students with dyslexia made on average twice as many spelling errors as the controls, with effect sizes of d ≥ 2. When the errors were classified as phonological, orthographic, or grammatical, we found a slight dominance of phonological errors in students with dyslexia. Sentence dictation did not provide more information than word dictation in the correct classification of students with and without dyslexia
Smart Cities: Towards a New Citizenship Regime? A Discourse Analysis of the British Smart City Standard
Growing practice interest in smart cities has led to calls for a less technology-oriented and more citizen-centric approach. In response, this articles investigates the citizenship mode promulgated by the smart city standard of the British Standards Institution. The analysis uses the concept of citizenship regime and a mixture of quantitative and qualitative methods to discern key discursive frames defining the smart city and the particular citizenship dimensions brought into play. The results confirm an explicit citizenship rationale guiding the smart city (standard), although this displays some substantive shortcomings and contradictions. The article concludes with recommendations for both further theory and practice development
Finite size giant magnons in the SU(2) x SU(2) sector of AdS_4 x CP^3
We use the algebraic curve and Luscher's mu-term to calculate the leading
order finite size corrections to the dispersion relation of giant magnons in
the SU(2) x SU(2) sector of AdS_4 x CP^3. We consider a single magnon as well
as one magnon in each SU(2). In addition the algebraic curve computation is
generalized to give the leading order correction for an arbitrary multi-magnon
state in the SU(2) x SU(2) sector.Comment: 19 pages; v2, v3: references added, typos fixe
Optogalvanic Spectroscopy of Metastable States in Yb^{+}
The metastable ^{2}F_{7/2} and ^{2}D_{3/2} states of Yb^{+} are of interest
for applications in metrology and quantum information and also act as dark
states in laser cooling. These metastable states are commonly repumped to the
ground state via the 638.6 nm ^{2}F_{7/2} -- ^{1}D[5/2]_{5/2} and 935.2 nm
^{2}D_{3/2} -- ^{3}D[3/2]_{1/2} transitions. We have performed optogalvanic
spectroscopy of these transitions in Yb^{+} ions generated in a discharge. We
measure the pressure broadening coefficient for the 638.6 nm transition to be
70 \pm 10 MHz mbar^{-1}. We place an upper bound of 375 MHz/nucleon on the
638.6 nm isotope splitting and show that our observations are consistent with
theory for the hyperfine splitting. Our measurements of the 935.2 nm transition
extend those made by Sugiyama et al, showing well-resolved isotope and
hyperfine splitting. We obtain high signal to noise, sufficient for laser
stabilisation applications.Comment: 8 pages, 5 figure
Simplifying superstring and D-brane actions in AdS(4) x CP(3) superbackground
By making an appropriate choice for gauge fixing kappa-symmetry we obtain a
relatively simple form of the actions for a D=11 superparticle in AdS(4) x
S(7)/Z_k, and for a D0-brane, fundamental string and D2-branes in the AdS(4) x
CP(3) superbackground. They can be used to study various problems of string
theory and the AdS4/CFT3 correspondence, especially in regions of the theory
which are not reachable by the OSp(6|4)/U(3) x SO(1,3) supercoset sigma-model.
In particular, we present a simple form of the gauge-fixed superstring action
in AdS(4) x CP(3) and briefly discuss issues of its T-dualization.Comment: 1+36 pages, v2,v3 clarifications and references adde
The AdS(4) x CP(3) string and its Bethe equations in the near plane wave limit
We perform a detailed study of bosonic type IIA string theory in a large
light-cone momentum / near plane wave limit of . In order to
attain this we derive the Hamiltonian up to cubic and quartic order in number
of fields and calculate the energies for string excitations in a subspace. The computation for the string energies is performed for
arbitrary length excitations utilizing an unitary transformation which allows
us to remove the cubic terms in the Hamiltonian. We then rewrite a recent set
of proposed all loop Bethe equations in a light-cone language and compare their
predictions with the obtained string energies. We find perfect agreement.Comment: 28 pages, references and footnote adde
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