4,803 research outputs found
Implementation and Outcome Evaluation of the Intensive Aftercare Program: Final Report
This Report presents the findings from a 5-year, multisite evaluation of the implementation and outcomes of the Intensive Aftercare Program (IAP), which was sponsored by the Office of Juvenile Justice and Delinquency Prevention (OJJDP). IAP was a major initiative in aftercare programming during the 1990s and has received considerable national attention. It addresses a critical problem facing the nation's juvenile justice system: how to effectively intervene with high-risk, incarcerated juvenile offenders who have demonstrated high recidivism rates and continue to offend as adults
Evaluation of techniques for removal of spacecraft contaminants from activated carbon
Alternative techniques for the regeneration of carbon contaminated with various spacecraft contaminants were evaluated. Four different modes of regeneration were evaluated: (1) thermal desorption via vacuum, (2) thermal desorption via nitrogen purge, (3) in-situ catalytic oxidation of adsorbed contaminants, and (4) in-situ non-catalytic oxidation of adsorbed contaminants
Weak charge form factor and radius of 208Pb through parity violation in electron scattering
We use distorted wave electron scattering calculations to extract the weak
charge form factor F_W(q), the weak charge radius R_W, and the point neutron
radius R_n, of 208Pb from the PREX parity violating asymmetry measurement. The
form factor is the Fourier transform of the weak charge density at the average
momentum transfer q=0.475 fm. We find F_W(q) =0.204 \pm 0.028 (exp) \pm
0.001 (model). We use the Helm model to infer the weak radius from F_W(q). We
find R_W= 5.826 \pm 0.181 (exp) \pm 0.027 (model) fm. Here the exp error
includes PREX statistical and systematic errors, while the model error
describes the uncertainty in R_W from uncertainties in the surface thickness
\sigma of the weak charge density. The weak radius is larger than the charge
radius, implying a "weak charge skin" where the surface region is relatively
enriched in weak charges compared to (electromagnetic) charges. We extract the
point neutron radius R_n=5.751 \pm 0.175 (exp) \pm 0.026 (model) \pm 0.005
(strange) fm$, from R_W. Here there is only a very small error (strange) from
possible strange quark contributions. We find R_n to be slightly smaller than
R_W because of the nucleon's size. Finally, we find a neutron skin thickness of
R_n-R_p=0.302\pm 0.175 (exp) \pm 0.026 (model) \pm 0.005 (strange) fm, where
R_p is the point proton radius.Comment: 5 pages, 1 figure, published in Phys Rev. C. Only one change in this
version: we have added one author, also to metadat
Soil fertility limits carbon sequestration by forest ecosystems in a CO2-enriched atmosphere
Northern mid-latitude forests are a large terrestrial carbon sink(1-4). Ignoring nutrient limitations, large increases in carbon sequestration from carbon dioxide (CO2) fertilization are expected in these forests(5). Yet, forests are usually relegated to sites of moderate to poor fertility, where tree growth is often limited by nutrient supply, in particular nitrogen(6,7). Here we present evidence that estimates of increases in carbon sequestration of forests, which is expected to partially compensate for increasing CO2 in the atmosphere, are unduly optimistic(8). In two forest experiments on maturing pines exposed to elevated atmospheric CO2, the CO2-induced biomass carbon increment without added nutrients was undetectable at a nutritionally poor site, and the stimulation at a nutritionally moderate site was transient, stabilizing at a marginal gain after three years. However, a large synergistic gain from higher CO2 and nutrients was detected with nutrients added. This gain was even larger at the poor site (threefold higher than the expected additive effect) than at the moderate site (twofold higher). Thus, fertility can restrain the response of wood carbon sequestration to increased atmospheric CO2. Assessment of future carbon sequestration should consider the limitations imposed by soil fertility, as well as interactions with nitrogen deposition.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62517/1/411469a0.pd
Identifying cardiac surgery operations in hospital episode statistics administrative database, with an OPCS-based classification of procedures, validated against clinical data
OBJECTIVES: Administrative databases with dedicated coding systems in healthcare systems where providers are funded based on services recorded have been shown to be useful for clinical research, although their reliability is still questioned. We devised a custom classification of procedures and algorithms based on OPCS, enabling us to identify open heart surgeries from the English administrative database, Hospital Episode Statistics, with the objective of comparing the incidence of cardiac procedures in administrative and clinical databases. DESIGN: A comparative study of the incidence of cardiac procedures in administrative and clinical databases. SETTING: Data from all National Health Service Trusts in England, performing cardiac surgery. PARTICIPANTS: Patients classified as having cardiac surgery across England between 2004 and 2015, using a combination of procedure codes, age >18 and consultant specialty, where the classification was validated against internal and external benchmarks. RESULTS: We identified a total of 296 426 cardiac surgery procedures, of which majority of the procedures were coronary artery bypass grafting (CABG), aortic valve replacement (AVR), mitral repair and aortic surgery. The matching at local level was 100% for CABG and transplant, >90% for aortic valve and major aortic procedures and >80% for mitral. At national level, results were similar for CABG (IQR 98.6%-104%), AVR (IQR 105%-118%) and mitral valve replacement (IQR 86.2%-111%). CONCLUSIONS: We set up a process which can identify cardiac surgeries in England from administrative data. This will lead to the development of a risk model to predict early and late postoperative mortality, useful for risk stratification, risk prediction, benchmarking and real-time monitoring. Once appropriately adjusted, the system can be applied to other specialties, proving especially useful in those areas where clinical databases are not fully established
The role of TcdB and TccC subunits in secretion of the photorhabdus Tcd toxin complex
The Toxin Complex (TC) is a large multi-subunit toxin encoded by a range of bacterial pathogens. The best-characterized examples are from the insect pathogens Photorhabdus, Xenorhabdus and Yersinia. They consist of three large protein subunits, designated A, B and C that assemble in a 5:1:1 stoichiometry. Oral toxicity to a range of insects means that some have the potential to be developed as pest control technology. The three subunit proteins do not encode any recognisable export sequences and as such little progress has been made in understanding their secretion. We have developed heterologous TC production and secretion models in E. coli and used them to ascribe functions to different domains of the crucial B+C sub-complex. We have determined that the B and C subunits use a secretion mechanism that is either encoded by the proteins themselves or employ an as yet undefined system common to laboratory strains of E. coli. We demonstrate that both the N-terminal domains of the B and C subunits are required for secretion of the whole complex. We propose a model whereby the N-terminus of the C-subunit toxin exports the B+C sub-complex across the inner membrane while that of the B-subunit allows passage across the outer membrane. We also demonstrate that even in the absence of the B-subunit, that the C-subunit can also facilitate secretion of the larger A-subunit. The recognition of this novel export system is likely to be of importance to future protein secretion studies. Finally, the identification of homologues of B and C subunits in diverse bacterial pathogens, including Burkholderia and Pseudomonas, suggests that these toxins are likely to be important in a range of different hosts, including man
A High Statistics Search for Electron-Neutrino --> Tau-Neutrino Oscillations
We present new limits on nu_e to nu_tau and nu_e to nu_sterile oscillations
by searching for electron neutrino dissappearance in the high-energy wide-band
CCFR neutrino beam. Sensitivity to nu_tau appearance comes from tau decay modes
in which a large fraction of the energy deposited is electromagnetic. The beam
is composed primarily of muon neutrinos but this analysis uses the 2.3%
electron neutrino component of the beam. Electron neutrino energies range from
30 to 600 GeV and flight lengths vary from 0.9 to 1.4 km. This limit improves
the sensitivity of existing limits and obtains a lowest 90% confidence upper
limit in sin**2(2*alpha) of 9.9 x 10**(-2) at delta-m**2 of 125 eV**2.Comment: submitted to Phys. Rev. D. Rapid Com
Teaching young consumers in Europe: a multicentre qualitative needs assessment with educators on food hygiene and food safety
Aim: Foodborne illnesses have a significant global burden and can be life-threatening, with higher risk in vulnerable groups such as children. SafeConsume is an EU-funded, transdisciplinary project aiming to improve consumers’ food safety behaviour. Developing educational resources on food safety for use in schools has potential to improve teaching of our young consumers. The aim of this study was to explore school educators’ attitudes, behaviours and knowledge towards food hygiene, safety and education. Methods: Focus groups and interviews in England, France, Portugal and Hungary explored educator knowledge, skills, intentions and beliefs around educating young people (11–18 years) about food safety. Data were analysed using NVivo and emerging themes were applied to the Theoretical Domains Framework. Results: A total of 48 educators participated. Knowledge, confidence and skills to teach food safety to young people varied depending on background and training. Educators reported they had a role to teach food safety to young people, were positive about delivering education and optimistic they could improve students’ food safety behaviour. Barriers to teaching included lack of national curriculum coverage, limited time and money, and lack of facilities. Educators reported that social influences (family, celebrity chefs, public health campaigns and social media) were important opportunities to improve young peoples’ awareness of food safety and consequences of foodborne illness. Conclusion: Educator food safety expertise varied; training could help to optimise educator knowledge, confidence and skills. Ministries of Health and Education need encouragement to get food safety incorporated further into school curricula across Europe, so schools will be motivated to prioritise these topics.info:eu-repo/semantics/publishedVersio
New Measurements of Nucleon Structure Functions from CCFR/NuTeV
We report on the extraction of the structure functions F_2 and Delta xF_3 =
xF_3nu-xF_3nub from CCFR neutrino-Fe and antineutrino-Fe differential cross
sections. The extraction is performed in a physics model independent (PMI) way.
This first measurement for Delta xF_3, which is useful in testing models of
heavy charm production, is higher than current theoretical predictions. Within
5% the F_2 (PMI) values measured in neutrino and muon scattering are in
agreement with the predictions of Next-to-Leading-Order PDFs (using massive
charm production schemes), thus resolving the long-standing discrepancy between
the two measurements.Comment: 3 pages, Presented by Arie Bodek at DPF2000 Conference, Columbus,
Ohio, Aug. 200
Teaching young consumers in Europe: a multicentre qualitative needs assessment with educators on food hygiene and food safety
Aim: Foodborne illnesses have a significant global burden and can be life-threatening, with higher risk in vulnerable groups such as children. SafeConsume is an EU-funded, transdisciplinary project aiming to improve consumers’ food safety behaviour. Developing educational resources on food safety for use in schools has potential to improve teaching of our young consumers. The aim of this study was to explore school educators’ attitudes, behaviours and knowledge towards food hygiene, safety and education. Methods: Focus groups and interviews in England, France, Portugal and Hungary explored educator knowledge, skills, intentions and beliefs around educating young people (11–18 years) about food safety. Data were analysed using NVivo and emerging themes were applied to the Theoretical Domains Framework. Results: A total of 48 educators participated. Knowledge, confidence and skills to teach food safety to young people varied depending on background and training. Educators reported they had a role to teach food safety to young people, were positive about delivering education and optimistic they could improve students’ food safety behaviour. Barriers to teaching included lack of national curriculum coverage, limited time and money, and lack of facilities. Educators reported that social influences (family, celebrity chefs, public health campaigns and social media) were important opportunities to improve young peoples’ awareness of food safety and consequences of foodborne illness. Conclusion: Educator food safety expertise varied; training could help to optimise educator knowledge, confidence and skills. Ministries of Health and Education need encouragement to get food safety incorporated further into school curricula across Europe, so schools will be motivated to prioritise these topics.N/
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