A systematic review of lesbian, gay, bisexual and transgender health in the West Midlands region of the UK compared to published UK research

It is estimated that approximately 3-8% of the UK population identify as lesbian, gay, bisexual or trans (LGBT). Until now, most health research on gay and bisexual men has been around HIV, AIDS and sexually transmitted diseases and for trans people has been on the transitioning process only. However, it has been apparent to the LGBT community that that there are a wide variety of other physical and mental health issues that are also important and that the proportion of gay and bisexual men who have HIV/AIDS is relatively small. Very little general LGBT health research has been published so far and there are very few health services that specifically address the general health concerns of the LGBT community. This systematic review presents all available research conducted in the West Midlands on LGBT health since 2000. Local health research is compared to UK national, peer reviewed and published LGBT health research in order to determine whether the local results are unusual compared to national LGBT data, and to routinely collected data on the UK population, where appropriate, in order to determine whether and where the LGBT population differ from the general population. Only UK research has been included because there was no previous UK specific systematic review so it was unclear how generalisable foreign research would be to the UK

A model balancing cooperation and competition explains our right-handed world and the dominance of left-handed athletes

An overwhelming majority of humans are right-handed. Numerous explanations for individual handedness have been proposed, but this population-level handedness remains puzzling. Here we use a minimal mathematical model to explain this population-level hand preference as an evolved balance between cooperative and competitive pressures in human evolutionary history. We use selection of elite athletes as a test-bed for our evolutionary model and account for the surprising distribution of handedness in many professional sports. Our model predicts strong lateralization in social species with limited combative interaction, and elucidates the rarity of compelling evidence for "pawedness" in the animal world.Comment: 5 pages of text and 3 figures in manuscript, 8 pages of text and two figures in supplementary materia

Rotorcraft digital advanced avionics system (RODAAS) functional description

A functional design of a rotorcraft digital advanced avionics system (RODAAS) to transfer the technology developed for general aviation in the Demonstration Advanced Avionics System (DAAS) program to rotorcraft operation was undertaken. The objective was to develop an integrated avionics system design that enhances rotorcraft single pilot IFR operations without increasing the required pilot training/experience by exploiting advanced technology in computers, busing, displays and integrated systems design. A key element of the avionics system is the functionally distributed architecture that has the potential for high reliability with low weight, power and cost. A functional description of the RODAAS hardware and software functions is presented

Multilocus genetic models of handedness closely resemble single-locus models in explaining family data and are compatible with genome-wide association studies.

Right- and left-handedness run in families, show greater concordance in monozygotic than dizygotic twins, and are well described by single-locus Mendelian models. Here we summarize a large genome-wide association study (GWAS) that finds no significant associations with handedness and is consistent with a meta-analysis of GWASs. The GWAS had 99% power to detect a single locus using the conventional criterion of P < 5 × 10(-8) for the single locus models of McManus and Annett. The strong conclusion is that handedness is not controlled by a single genetic locus. A consideration of the genetic architecture of height, primary ciliary dyskinesia, and intelligence suggests that handedness inheritance can be explained by a multilocus variant of the McManus DC model, classical effects on family and twins being barely distinguishable from the single locus model. Based on the ENGAGE meta-analysis of GWASs, we estimate at least 40 loci are involved in determining handedness

Cross-comparison of MRCGP & MRCP(UK) in a database linkage study of 2,284 candidates taking both examinations: assessment of validity and differential performance by ethnicity.

MRCGP and MRCP(UK) are the main entry qualifications for UK doctors entering general [family] practice or hospital [internal] medicine. The performance of MRCP(UK) candidates who subsequently take MRCGP allows validation of each assessment. In the UK, underperformance of ethnic minority doctors taking MRCGP has had a high political profile, with a Judicial Review in the High Court in April 2014 for alleged racial discrimination. Although the legal challenge was dismissed, substantial performance differences between white and BME (Black and Minority Ethnic) doctors undoubtedly exist. Understanding ethnic differences can be helped by comparing the performance of doctors who take both MRCGP and MRCP(UK)

How Efficient is Market Pricing: Can Investors Beat the Market? Further, are Prices Always Right as Stated in the Efficient Market Hypothesis?

The Efficient Market Hypothesis is a widely accepted economic theory developed by economist Eugene Fama. The theory states that at any given time, an asset’s price reflects all available public information and will always trade at fair value. The motivation for this research is derived from the content taught in undergraduate finance courses. In undergraduate academia finance students are introduced to the idea of market efficiency, as it is a building block for future theory and application. However, this theory is rarely questioned in the world of undergraduate academia, rather just taken as fact by students. The underlying research in this paper attempts to answer a key question in the investment world of “are asset prices always right as stated in the EMH?”. If asset prices are always trading at fair value, individuals cannot achieve a return on investment that is higher than the market average, rendering active management useless. This research has concluded that there are times where assets are not priced to fair value. This is not to say that the EMH is wrong, but rather ‘not right’ 100% of the time. Market inefficiency is driven by three main factors that will be mentioned in this paper: (1) Investor cognitive error (2) Market disruptions and illiquidity (3) Investor emotions (fear & greed). Throughout the paper there will be examples of both extremely efficient & inefficient market pricing. This paper will prove useful for any finance student or recreational investor who has never challenged the EMH and is attempting to form their own opinion on market efficiency

The Characterization of a New Metabolite from a Trichodesmium Bloom

Our laboratory has been investigating blooms of Trichodesmium, a genus of ecologically important, nitrogen-fixing cyanobacteria, collected from Padre Island in the Gulf of Mexico. Trichodesmium species are an underexplored biological source of cyanobacteria – a taxa that has been shown to produce chemically diverse secondary metabolites. With our focus on the isolation and structure characterization of new bioactive marine natural products, our research group has discovered over 25 new-to-science compounds over the past three years from these blooms. UV and mass spectrometry-guided isolation of Trichodesmium chromatography fractions were utilized to isolate a new metabolite. Isolation of this metabolite was carried out by means of silica gel vacuum liquid chromatography, solid phase extraction chromatography, and high-performance liquid chromatography. The structure of this molecule was determined using high-resolution mass spectrometry along with 1D and 2D NMR analysis. The molecule contains interesting structural features such as a lactone ring and an aldehyde functional group. This molecule is similar to 11 others isolated by the Bertin laboratory in a group named the trichophycins. However, this new metabolite does not feature a chlorovinylidene moiety, which is a hallmark of the trichophycins. The isolation and characterization of this molecule adds to our laboratory’s pure compound library and provides a new entity to screen for biological activity. Furthermore, inspection of the structure of this new metabolite provokes questions as to its biosynthesis

A study of the opinions of seventy-one classroom teachers and twelve public health nurses about the activities the nurse should perform in a school health program

Thesis (M.S.)--Boston Universit