2,827 research outputs found

    Fuel cycles in nuclear reactors

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    Series numbering from publisher's list"61"--stamped on cover"Unclassified. NYO-2131."Originally issued by the first author as an Sc. D. thesis, Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1959Contract AT(30-1)-207

    SpxA1 and SpxA2 act coordinately to fine-tune stress responses and virulence in Streptococcus pyogenes

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    SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an antiactivator. Why some Firmicutes members have two highly similar SpxA paralogs is not understood. Here, we show that the SpxA paralogs of the pathogen Streptococcus pyogenes, SpxA1 and SpxA2, act coordinately to regulate virulence by fine-tuning toxin expression and stress resistance. Construction and analysis of mutants revealed that SpxA1− mutants were defective for growth under aerobic conditions, while SpxA2− mutants had severely attenuated responses to multiple stresses, including thermal and oxidative stresses. SpxA1− mutants had enhanced resistance to the cationic antimicrobial molecule polymyxin B, while SpxA2− mutants were more sensitive. In a murine model of soft tissue infection, a SpxA1− mutant was highly attenuated. In contrast, the highly stress-sensitive SpxA2− mutant was hypervirulent, exhibiting more extensive tissue damage and a greater bacterial burden than the wild-type strain. SpxA1− attenuation was associated with reduced expression of several toxins, including the SpeB cysteine protease. In contrast, SpxA2− hypervirulence correlated with toxin overexpression and could be suppressed to wild-type levels by deletion of speB. These data show that SpxA1 and SpxA2 have opposing roles in virulence and stress resistance, suggesting that they act coordinately to fine-tune toxin expression in response to stress. SpxA2− hypervirulence also shows that stress resistance is not always essential for S. pyogenes pathogenesis in soft tissue

    Distinguishing high-mass binary neutron stars from binary black holes with second- and third-generation gravitational wave observatories

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    (Abridged) While the gravitational-wave (GW) signal GW170817 was accompanied by a variety of electromagnetic (EM) counterparts, sufficiently high-mass binary neutron star (BNS) mergers are expected to be unable to power bright EM counterparts. The putative high-mass binary BNS merger GW190425, for which no confirmed EM counterpart has been identified, may be an example of such a system. It is thus important to understand how well we will be able to distinguish high-mass BNSs and low-mass binary black holes (BBHs) solely from their GW signals. To do this, we consider the imprint of the tidal deformability of the neutron stars on the GW signal for systems undergoing prompt black hole formation after merger. We model the BNS signals using hybrid numerical relativity -- tidal effective-one-body waveforms. Specifically, we consider a set of five nonspinning equal-mass BNS signals with masses of 2.7, 3.0, 3.2 Msun and with three different equations of state, as well as the analogous BBH signals. We perform parameter estimation on these signals in three networks: Advanced LIGO-Advanced Virgo and Advanced LIGO-Advanced Virgo-KAGRA with sensitivities similar to O3 and O4, respectively, and a 3G network of two Cosmic Explorers (CEs) and one Einstein Telescope, with a CE sensitivity similar to Stage 2. Our analysis suggests that we cannot distinguish the signals from high-mass BNSs and BBHs at a 90% credible level with the O3-like network even at 40 Mpc. However, we can distinguish all but the most compact BNSs that we consider in our study from BBHs at 40 Mpc at a >= 95% credible level using the O4-like network, and can even distinguish them at a > 99.2% (>= 97%) credible level at 369 (835) Mpc using the 3G network. Additionally, we present a simple method to compute the leading effect of the Earth's rotation on the response of a gravitational wave detector in the frequency domain

    Inverse-kinematics one-neutron pickup with fast rare-isotope beams

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    New measurements and reaction model calculations are reported for single neutron pickup reactions onto a fast \nuc{22}{Mg} secondary beam at 84 MeV per nucleon. Measurements were made on both carbon and beryllium targets, having very different structures, allowing a first investigation of the likely nature of the pickup reaction mechanism. The measurements involve thick reaction targets and γ\gamma-ray spectroscopy of the projectile-like reaction residue for final-state resolution, that permit experiments with low incident beam rates compared to traditional low-energy transfer reactions. From measured longitudinal momentum distributions we show that the \nuc{12}{C} (\nuc{22}{Mg},\nuc{23}{Mg}+\gamma)X reaction largely proceeds as a direct two-body reaction, the neutron transfer producing bound \nuc{11}{C} target residues. The corresponding reaction on the \nuc{9}{Be} target seems to largely leave the \nuc{8}{Be} residual nucleus unbound at excitation energies high in the continuum. We discuss the possible use of such fast-beam one-neutron pickup reactions to track single-particle strength in exotic nuclei, and also their expected sensitivity to neutron high-ℓ\ell (intruder) states which are often direct indicators of shell evolution and the disappearance of magic numbers in the exotic regime.Comment: 8 pages, 5 figure

    In-beam gamma-ray spectroscopy of 35Mg and 33Na

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    Excited states in the very neutron-rich nuclei 35Mg and 33Na were populated in the fragmentation of a 38Si projectile beam on a Be target at 83 MeV/u beam energy. We report on the first observation of gamma-ray transitions in 35Mg, the odd-N neighbor of 34Mg and 36Mg, which are known to be part of the "Island of Inversion" around N = 20. The results are discussed in the framework of large- scale shell-model calculations. For the A = 3Z nucleus 33Na, a new gamma-ray transition was observed that is suggested to complete the gamma-ray cascade 7/2+ --> 5/2+ --> 3/2+ gs connecting three neutron 2p-2h intruder states that are predicted to form a close-to-ideal K = 3/2 rotational band in the strong-coupling limit.Comment: Accepted for publication Phys. Rev. C. March 16, 2011: Replaced figures 3 and 5. We thank Alfredo Poves for pointing out a problem with the two figure

    Temperature dependence of binary and ternary recombination of H3+ ions with electron

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    We study binary and the recently discovered process of ternary He-assisted recombination of H3+ ions with electrons in a low temperature afterglow plasma. The experiments are carried out over a broad range of pressures and temperatures of an afterglow plasma in a helium buffer gas. Binary and He-assisted ternary recombination are observed and the corresponding recombination rate coefficients are extracted for temperatures from 77 K to 330 K. We describe the observed ternary recombination as a two-step mechanism: First, a rotationally-excited long-lived neutral molecule H3* is formed in electron-H3+ collisions. Second, the H3* molecule collides with a helium atom that leads to the formation of a very long-lived Rydberg state with high orbital momentum. We present calculations of the lifetimes of H3* and of the ternary recombination rate coefficients for para and ortho-H3+. The calculations show a large difference between the ternary recombination rate coefficients of ortho- and para-H3+ at temperatures below 300 K. The measured binary and ternary rate coefficients are in reasonable agreement with the calculated values.Comment: 15 page

    Regulated Emissions from Biodiesel Tested in Heavy-Duty Engines Meeting 2004 Emission Standards

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    Biodiesel produced from soybean oil, canola oil, yellow grease, and beef tallow was tested in two heavy-duty engines. The biodiesels were tested neat and as 20% by volume blends with a 15 ppm sulfur petroleum-derived diesel fuel. The test engines were the following: 2002 Cummins ISB and 2003 DDC Series 60. Both engines met the 2004 U.S. emission standard of 2.5 g/bhp-h NO{sub x}+HC (3.35 g/kW-h) and utilized exhaust gas recirculation (EGR). All emission tests employed the heavy-duty transient procedure as specified in the U.S. Code of Federal Regulations. Reduction in PM emissions and increase in NO{sub x} emissions were observed for all biodiesels in all engines, confirming observations made in older engines. On average PM was reduced by 25% and NO{sub x} increased by 3% for the two engines tested for a variety of B20 blends. These changes are slightly larger in magnitude, but in the same range as observed in older engines. The cetane improver 2-ethyl hexyl nitrate was shown to have no measurable effect on NO{sub x} emissions from B20 in these engines, in contrast to observations reported for older engines. The effect of intake air humidity on NO{sub x} emissions from the Cummins ISB was quantified. The CFR NO{sub x}/humidity correction factor was shown to be valid for an engine equipped with EGR, operating at 1700 m above sea level, and operating on conventional or biodiesel
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