1,619 research outputs found
Synthetically-focused surface-penetrating radar for operation from a moving vehicle
This paper reports on a research programme, started recently under DERA sponsorship, on applying synthetic focusing to an oblong horizontal stand-off array, where all the voxels in a vertical slice underneath the centre-line of the array are synthesised electronically, with the third dimension provided by the search vehicle's forward movement. This should permit a very high search rate for buried mines, in a wide range of ground conditions
Metastatic melanoma to the pituitary gland
Journal ArticleMetastasis to the pituitary gland is unusual, and occurs most often in patients with carcinomas of the breast or lung. Despite its propensity for spread to the brain, metastatic melanoma has rarely been described within the sella. Methods: We report two cases of malignant melanoma pathologically confirmed within the pituitary, both metastatic from a primary site on the chest wall. In each patient, transsphenoidal resection of the tumor was incomplete and each received local radiotherapy after surgery. Results: One patient recurred quickly and developed brain metastasis as well. He died four months after resection of the pituitary metastasis, but the second patient survived six months without recurrence. As intrasellar metastasis portends widespread systemic disease and may be synchronous with parenchymal brain metastasis, survival in such patients is limited regardless of adjunctive therapy. Conclusions: Such cases are likely to arise more commonly in future due to the increasing incidence of melanoma. Identifying them by imaging alone is difficult due to inconsistent signal characteristics on MRI (as shown by these cases) and the confusion introduced by any associated intratumoral hemorrhage
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