DESEMPENHO PRODUTIVO DE CULTIVARES DE CABOTIÁ EM NOVO SÃO JOAQUIM, MATO GROSSO

A escolha de uma cultivar adaptada às características edafoclimáticas da região e às condições de cultivo são fundamentais para o êxito na produção agrícola. O objetivo desse trabalho foi avaliar o desempenho agronômico de cultivares de cabotiá no município de Novo São Joaquim, Mato Grosso. O experimento foi realizado empregando-se o delineamento em blocos casualizados. Foram avaliadas sete cultivares de cabotiá: Takayama; Kyoto, Chikara; Kampai; Kanda; B8A; Atakama. As variáveis analisadas foram: produção por planta, massa fresca, altura e diâmetro transversal dos frutos. A partir desses dados foram obtidas a produtividade total e produtividade por classe de tamanho dos frutos. Não houve diferença estatística para a produtividade e tamanho médio dos frutos, porém, houve variação na distribuição da produção por classe de tamanhos dos frutos. Os valores encontrados para tamanho dos frutos e produtividade ficaram próximos aos citados na literatura. Apesar do trabalho fornecer informações inéditas para a região, não foi possível determinar a cultivar mais adequada para o plantio. Concluiu-se que o município apresenta potencial agronômico para o cultivo comercial de cabotiá

Cysticercosis in free-ranging agoutis (Dasyprocta leporina) in the Eastern Brazilian Amazon

Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Patologia. São Paulo, SP, Brasil / Universidade Paulista. Instituto de Ciências da Saúde. Campinas, SP, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Centro Nacional de Primatas. Ananindeua, PA, Brasil.Universidade de São Paulo. Instituto de Medicina Tropical. Departamento de Gastroenterologia. São Paulo, SP, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Instituto Evandro Chagas. Ananindeua, PA, Brasil.The study describes the occurrence of cysticercosis in liver of 22 wild agoutis (Dasyprocta leporina) in the Brazilian Amazon. The phylogenetic analysis and microscopic characteristics of metacestodes in liver tissue sections, associated with the geographic distribution of the intermediate hosts indicated that a possibly novel Taenia sp. metacestode caused the parasitism. Additionally, two cases of hepatic co-infection by Taenia sp., Calodium sp. and Echinococcus oligarthra were also observed among the analyzed animals. The results point to the need for a better understanding of hepatotropic parasites among wild rodents in the Brazilian Amazon

Squash Kabocha produtivity grown in intercropping and monocrop

Evaluated the productivity of experimental squash kabocha "HC02 IF Goiano" intercropped with different green manures and annual crops. The experimental design was randomized blocks with eight treatments and three replications. The treatments were: (1) Squash hybrid HC02 IFGoiano (monocrop); (2) Squash kabocha HC02 IFGoiano intercropped with maize cv. "BM 3061"; (3) Squash kabocha HC02 IFGoiano intercropped with sunflower cv. "BRS 321"; (4) Squash kabocha HC02 IF Goiano intercropped with peanut cv. "common"; (5) Squash kabocha HC02 IF Goiano intercropped with pigeon pea dwarf cv. "IAPAR 43"; (6) Squash kabocha HC02 IF Goiano intercropped with pigeon pea shrub cv. "Super N"; (7) Squash kabocha HC02 IF Goiano intercropped with Crotalaria spectabilis cv. "common" and (8) Squash kabocha HC02 IF Goiano intercropped with Crotalaria juncea cv. "common". Treatments that exerted more negative effects on productivity squash kabocha was sunflower and pigeon pea shrub, with no significant differences in intercropped with maize, pigeon pea dwarf and C. juncea. The squash kabocha HC02 IFGoiano had positive impacts when in consortium with Peanut and C. spectabilis, resulting in an equivalent yield to the treatment monocrop. We conclude that it is not recommended intercropping with maize, sunflower, C. juncea and pigeon pea evaluated in agronomic conditions. The intercropping can be adopted without prejudice to the productivity of experimental squash kabocha HC02 IFGoiano with C. spectabilis and peanuts.The productivity of experimental squash kabocha “HC02 IF Goiano”, intercropped with different green manures and annual crops, were evaluated. The experimental design was randomized blocks with eight treatments and three replications. The treatments were: (1) Squash hybrid HC02 IFGoiano (monocrop); (2) Squash kabocha HC02 IFGoiano intercropped with maize cv. “BM 3061”; (3) Intercropped with sunflower cv. “BRS 321”; (4) Intercropped with peanut cv. “common”; (5) Intercropped with pigeon pea dwarf cv. “IAPAR 43”; (6) Intercropped with pigeon pea shrub cv. “Super N”; (7) Intercropped with Crotalaria spectabilis cv. “common” and (8) Intercropped with Crotalaria juncea cv. “common”. Treatments that exerted more negative effects on productivity of squash kabocha were sunflower and pigeon pea shrub, with no significant differences in intercropped with maize, pigeon pea dwarf and C. juncea. The squash kabocha HC02 IFGoiano had positive impacts when in consortium with peanut and C. spectabilis, resulting in an equivalent yield to the treatment monocrop. We conclude that it is not recommended intercropping with maize, sunflower, C. juncea and pigeon pea in these agronomic conditions. The intercropping can be adopted without reduction of productivity of experimental squash kabocha HC02 IFGoiano with C. spectabilis and peanuts

SEROLOGICAL DETECTION OF HEPATITIS A VIRUS IN FREE-RANGING NEOTROPICAL PRIMATES (Sapajus spp., Alouatta caraya) FROM THE PARANÁ RIVER BASIN, BRAZIL

Nonhuman primates are considered as the natural hosts of Hepatitis A virus (HAV), as well as other pathogens, and can serve as natural sentinels to investigate epizootics and endemic diseases that are of public health importance. During this study, blood samples were collected from 112 Neotropical primates (NTPs) (Sapajus nigritus and S. cay, n = 75; Alouatta caraya, n = 37) trap-captured at the Paraná River basin, Brazil, located between the States of Paraná and Mato Grosso do Sul. Anti-HAV IgG antibodies were detected in 4.5% (5/112) of NTPs, specifically in 6.7% (5/75) of Sapajus spp. and 0% (0/37) of A. caraya. In addition, all samples were negative for the presence of IgM anti-HAV antibodies. These results suggest that free-ranging NTPs were exposed to HAV within the geographical regions evaluated

SEROLOGICAL DETECTION OF HEPATITIS A VIRUS IN FREE-RANGING NEOTROPICAL PRIMATES (Sapajus spp., Alouatta caraya) FROM THE PARANÁ RIVER BASIN, BRAZIL

Nonhuman primates are considered as the natural hosts of Hepatitis A virus (HAV), as well as other pathogens, and can serve as natural sentinels to investigate epizootics and endemic diseases that are of public health importance. During this study, blood samples were collected from 112 Neotropical primates (NTPs) (Sapajus nigritus and S. cay, n = 75; Alouatta caraya, n = 37) trap-captured at the Paraná River basin, Brazil, located between the States of Paraná and Mato Grosso do Sul. Anti-HAV IgG antibodies were detected in 4.5% (5/112) of NTPs, specifically in 6.7% (5/75) of Sapajus spp. and 0% (0/37) of A. caraya. In addition, all samples were negative for the presence of IgM anti-HAV antibodies. These results suggest that free-ranging NTPs were exposed to HAV within the geographical regions evaluated

SESSÃO 3Rs

BIOINSECTICIDAL ACTION OF ESSENTIAL OIL OF lantanamontevidensis BRIQ. AGAINSTDrosophilamelanogaster. /ETHICAL ASPECTS IN ANIMAL EXPERIMENTATION IN BRAZIL: A REVIEW. /COMPLIANCE WITH THE AROUCA LAW IN TEACHING PHARMACOLOGY IN THE MEDICINE COURSE - UFC SOBRAL. /TOXICOLOGICAL ACTIVITY AGAINST Artemiasalina LEACH FROM Hyptissuaveolens (L.) POIT. /TOXICOLOGICAL ACTIVITY OF THE AQUEOUS EXTRACT OF LEAVES OF Tarenayaspinosa (JACQ.) RAF. AGAINST Artemiasalina LEACH. /ANIMAL CADAVER BANK AS AN ALTERNATIVE TEACHING MODEL FOR HIGHER EDUCATION. /BIOINFORMATICS AS A TOOL FOR REDUCING THE NUMBER OF ANIMALS: DETERMINING THE MOST EFFECTIVE TYPE OF PHYSICAL EXERCISE IN THE THERAPY OF ALZHEIMER'S DISEASE. /CELL CULTURE-GUIDED OOCYTE COLLECTION FOR THE STUDY OF MICROSPORIDIOSIS: A FEASIBLE ALTERNATIVE APPLIED TO THE PRINCIPLE OF THE 3Rs. /ANTIOXIDANT EFFECT OF ANETHOLE IN THE IN VITRO CULTURE OF ISOLATED PREANTRAL FOLLICLES. /THE USE OF SOFTWARE AS AN ALTERNATIVE IN THE EVALUATION OF TOXICITY. /FISH AS EXPERIMENTAL ANIMALS: USE AND LEGISLATION. /REDUCING ANIMAL USE THROUGH BIOINFORMATICS: INS-L-CO TECHNIQUES INDICATE MOLECULAR TARGETS. /ACUTE TOXICITY IN SWISS MICE AND TOXICITY TO Artemiasalina FROM THE ACETATE FRACTION OF Calotropisprocera (AIT.) LATEX (APOCYNACEAE). /TOXICITY OF THE AQUEOUS EXTRACT OF THE LEAVES OF Hyptissuaveolens (L.) POIT. AGAINST Artemiasalina LEACH. /USE OF CELL AND TISSUE CULTURES AS A SUBSTITUTE FOR ANIMAL USE: A REVIEWAÇÃO BIOINSETICIDA DO ÓLEO ESSENCIAL DE lantanamontevidensis BRIQ. CONTRADrosophilamelanogaster. /ASPECTOS ÉTICOS EM EXPERIMENTAÇÃO ANIMAL NO BRASIL: UMA REVISÃO. /ATENDIMENTO À LEI AROUCA NO ENSINO DE FARMACOLOGIA NO CURSO DE MEDICINA - UFC  SOBRAL. /ATIVIDADE TOXICOLÓGICA CONTRA Artemiasalina LEACH DA Hyptissuaveolens (L.) POIT. /ATIVIDADE TOXICOLÓGI CA DO EXTRATO AQUOSO DAS FOLHAS DE Tarenayaspinosa (JACQ.) RAF. CONTRA Artemiasalina LEACH. /BANCO DE CADÁVERES ANIMAL COMO MODELO DIDÁTICO ALTERNATIVO PARA O ENSINO SUPERIOR. /BIOINFORMÁTICA COMO FERRAMENTA PARA REDUÇÃO DO NÚMERO DE ANIMAIS: A DETERMINAÇÃO DO TIPO DE EXERCÍCIO FÍSICO MAIS EFICAZ NA TERAPÊUTICA DA DOENÇA DE ALZHEIMER. /COLHEITA DE OÓCITOS GUIADA POR CULTURA DE CÉLULAS PARA O ESTUDO DA MICROSPORI DIOSE: UMA ALTERNATIVA FACTÍVEL E APLICADA AO PRINCÍPIO DOS 3Rs. /EFEITO ANTIOXIDANTES DO ANETOL NO CULTIVO IN VITRO DE FOLÍCULOS PRÉ-ANTRAIS ISOLADOS. /O USO DE SOFTWARES COMO ALTERNATIVA NA AVALIAÇÃO DE TOXICIDADE. /PEIXES COMO ANIMAIS DE EXPERIMENTAÇÃO: UTILIZAÇÃO E LEGISLAÇÃO. /REDUÇÃO DO USO DE ANIMAIS ATRAVÉS DA BIOINFORMÁTICA: TÉCNICAS INS-L-CO APONTAM ALVOS MOLECULARES. /TOXICIDADE AGUDA EM CAMUNDONGOS SWISS E TOXICIDADE FRENTE À Artemiasalina DA FRAÇÃO ACETATO DO LÁTEX DE Calotropisprocera( AIT.) (APOCYNACEAE). /TOXICIDADE DO EXTRATO AQUOSO DAS FOLHAS DE Hyptissuaveolens (L.) POIT. CONTRA Artemiasalina LEACH. /USO DE CULTURA DE CÉLULAS E TECIDOS COMO SUBSTITUTO À UTILIZAÇÃO DE ANIMAIS: UMA REVISÃ

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

Background: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050. Methods: Using forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. Cause-specific mortality was modelled using mixed-effects models with SDI and time as the main covariates, and the combined impact of causal risk factors as an offset in the model. At the all-cause mortality level, we captured unexplained variation by modelling residuals with an autoregressive integrated moving average model with drift attenuation. These all-cause forecasts constrained the cause-specific forecasts at successively deeper levels of the GBD cause hierarchy using cascading mortality models, thus ensuring a robust estimate of cause-specific mortality. For non-fatal measures (eg, low back pain), incidence and prevalence were forecasted from mixed-effects models with SDI as the main covariate, and YLDs were computed from the resulting prevalence forecasts and average disability weights from GBD. Alternative future scenarios were constructed by replacing appropriate reference trajectories for risk factors with hypothetical trajectories of gradual elimination of risk factor exposure from current levels to 2050. The scenarios were constructed from various sets of risk factors: environmental risks (Safer Environment scenario), risks associated with communicable, maternal, neonatal, and nutritional diseases (CMNNs; Improved Childhood Nutrition and Vaccination scenario), risks associated with major non-communicable diseases (NCDs; Improved Behavioural and Metabolic Risks scenario), and the combined effects of these three scenarios. Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. Life expectancy and healthy life expectancy were computed using standard methods. The forecasting framework includes computing the age-sex-specific future population for each location and separately for each scenario. 95% uncertainty intervals (UIs) for each individual future estimate were derived from the 2·5th and 97·5th percentiles of distributions generated from propagating 500 draws through the multistage computational pipeline. Findings: In the reference scenario forecast, global and super-regional life expectancy increased from 2022 to 2050, but improvement was at a slower pace than in the three decades preceding the COVID-19 pandemic (beginning in 2020). Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. At the super-region level, forecasted healthy life expectancy patterns were similar to those of life expectancies. Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. We also forecasted that both DALY counts and age-standardised DALY rates will continue to shift from CMNNs to NCDs, with the most pronounced shifts occurring in sub-Saharan Africa (60·1% [95% UI 56·8–63·1] of DALYs were from CMNNs in 2022 compared with 35·8% [31·0–45·0] in 2050) and south Asia (31·7% [29·2–34·1] to 15·5% [13·7–17·5]). This shift is reflected in the leading global causes of DALYs, with the top four causes in 2050 being ischaemic heart disease, stroke, diabetes, and chronic obstructive pulmonary disease, compared with 2022, with ischaemic heart disease, neonatal disorders, stroke, and lower respiratory infections at the top. The global proportion of DALYs due to YLDs likewise increased from 33·8% (27·4–40·3) to 41·1% (33·9–48·1) from 2022 to 2050, demonstrating an important shift in overall disease burden towards morbidity and away from premature death. The largest shift of this kind was forecasted for sub-Saharan Africa, from 20·1% (15·6–25·3) of DALYs due to YLDs in 2022 to 35·6% (26·5–43·0) in 2050. In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. The Safer Environment scenario had its largest decrease in sub-Saharan Africa (5·2% [3·5–6·8]), the Improved Behavioural and Metabolic Risks scenario in north Africa and the Middle East (23·2% [20·2–26·5]), and the Improved Nutrition and Vaccination scenario in sub-Saharan Africa (2·0% [–0·6 to 3·6]). Interpretation: Globally, life expectancy and age-standardised disease burden were forecasted to improve between 2022 and 2050, with the majority of the burden continuing to shift from CMNNs to NCDs. That said, continued progress on reducing the CMNN disease burden will be dependent on maintaining investment in and policy emphasis on CMNN disease prevention and treatment. Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions