485 research outputs found
One-dimensional multicomponent Fermi gas in a trap: quantum Monte Carlo study
One-dimensional world is very unusual as there is an interplay between
quantum statistics and geometry, and a strong short-range repulsion between
atoms mimics Fermi exclusion principle, fermionizing the system. Instead, a
system with a large number of components with a single atom in each, on the
opposite acquires many bosonic properties. We study the ground-state properties
a multi-component Fermi gas trapped in a harmonic trap by fixed-node diffusion
Monte Carlo method. We investigate how the energetic properties (energy,
contact) and correlation functions (density profile and momentum distribution)
evolve as the number of components is changed. It is shown that the system
fermionizes in the limit of strong interactions. Analytical expression are
derived in the limit of weak interactions within the local density
approximation for arbitrary number of components and for one plus one particle
using an exact solution.Comment: 15 pages, 5 figure
Soluble triggering receptor expressed on myeloid cells as a marker of non-infectious systemic inflammatory response syndrome
Comparative characteristics of biochemical composition of synovial fluid of knee and elbow human joints
The purpose of this study was comparative analysis of normal biochemical composition of synovial fluid of knee and elbow human joints. Studies were performed on synovial fluid samples of 33 cadavers of suddenly dead people of both sexes (26 men and. 7 women) at the age of 23 to 79 years, without articular pathology registered by expert. We didn't reveal reliable differences of albumen-globulin coefficient, but there were differences in contents of albumen fractions, products of oxide peroxidation of albumens. At the developement of pathological process cast of albumen in synovial fluid is possibly the compensatory reaction in providing of synovia viscosity, because albumen component provides this function on level with hyaluronic acid. Knee joint is an hinge joint, that is meant to bend only in one plane. Biomechanics of elbow joint is much more complicated and. is described as "ginglymoid hinge" with abduction-adduction besides the joint is much smaller. Obtained results can be used as normative values of biochemical synovial fluid indexes in orthopaedic and. trauma practic
Erosion yields of carbon under various plasma conditions in Pilot-PSI
Fine-grain graphite targets have been exposed to ITER divertor relevant
plasmas in Pilot-PSI to address material migration issues in fusion devices.
Optical emission spectroscopy and mass loss measurements have been employed to
quantify gross chemical erosion and net erosion yields, respectively. Effects
of the ion impact energy and target geometry on carbon erosion yields have been
studied. It is concluded that temporal evolution of gross chemical erosion is
strongly connected with changes in morphology of plasma exposed surfaces. The
net carbon erosion yield is increased when the targets are partly covered by
insulating boron-nitride rings.Comment: 14 pages, 4 figures, Contribution to the 19th International
Conference on Plasma Surface Interaction
The pedagogical potential of socio-cultural creativity in shaping the culture of interethnic communication of student's youth
© 2017 Serials Publications.The article is devoted to the interconnections and relationships, during which young people belong to different ethnic communities and different religious views, exchange experiences, spiritual values, thoughts, feelings. The value of building a culture of inter-ethnic communication is that it stimulates the activity of the youth social sphere, provides the formation of a multicultural mentality, sociocultural identity binds the individual to the social, creative and spiritual life. The stages of development of culture of international youth dialogue analysis are presented. The article presents the results of the body of research the formation of culture of international dialogue of youth by means of social and cultural creativity. Materials of article can be recommended for the development of culture of interethnic communication in the context of social and cultural creativity in a variety of leisure and social and cultural centers for youth work
IMMUNOSUPPRESSION AS A COMPONENT OF MULTIPLE ORGAN DYSFUNCTION SYNDROME FOLLOWING CARDIAC SURGERY
Aim. To defne the role of myeloid-derived suppressor cells in the development of persistent multiple organ dysfunction followed cardiac surgeries with cardiopulmonary bypass.Methods. 40 patients who have undergone cardiac surgery were included in the study. Granulocyte myeloid-derived suppressor cells (G-MDSC) were defned as cells with the HLA-DR– / CD11β+ / CD15+ / CD33+ phenotype, and monocytic MDSC (M-MDSC) as cells with the HLA-DR– / CD11β+ / CD14+ / CD33+ phenotype using flow cytometry. Levels of cytokines, IL-1β, IL-6, TNF-α, and IL-10 were measured with an enzyme immunoassay. All patients were assigned to three groups: Group 1 – patients with the uncomplicated postoperative period (n = 14), Group 2 – patients with non-persistent MODS and its early resolution (n = 16), and Group 3 – patients with persistent MODS at day 7.Results. We observed an increase in M-MDSCs and G-MDSC at day 1 following cardiac surgery. The most pronounced increase was found in monocytic-myeloid derived suppressor cells, i.e. an 8-fold increase in M-MDSCs in all study groups at day 1 after surgery. The number of M-MDSCs remained high in patients with persistent MODS at day 7 after cardiac surgery. Levels of IL-6 and IL-10 increased at day 1 after surgery. IL-6 reached its peak level, signifcantly exceeding baseline levels. By day 7, blood levels of all cytokines have decreased, except IL-10 levels, which remained above the baseline in patients with persistent MODS.Conclusion. An increase in M-MDSCs and elevated serum levels of the anti-inflammatory cytokine IL-10 have been found in patients regardless of the presence or absence of the complications in the early postoperative period after cardiac surgery with cardiopulmonary bypass. Persistent MODS with the SOFA scoring > 5 scores at day 7 after cardiac surgery, is associated with an increase in M-MDSCs and elevated levels of the anti-inflammatory cytokine IL-10, related to higher rate of hospital infections, prolonged intensive care unit stay and higher mortality.Aim. To defne the role of myeloid-derived suppressor cells in the development of persistent multiple organ dysfunction followed cardiac surgeries with cardiopulmonary bypass.Methods. 40 patients who have undergone cardiac surgery were included in the study. Granulocyte myeloid-derived suppressor cells (G-MDSC) were defned as cells with the HLA-DR– / CD11β+ / CD15+ / CD33+ phenotype, and monocytic MDSC (M-MDSC) as cells with the HLA-DR– / CD11β+ / CD14+ / CD33+ phenotype using flow cytometry. Levels of cytokines, IL-1β, IL-6, TNF-α, and IL-10 were measured with an enzyme immunoassay. All patients were assigned to three groups: Group 1 – patients with the uncomplicated postoperative period (n = 14), Group 2 – patients with non-persistent MODS and its early resolution (n = 16), and Group 3 – patients with persistent MODS at day 7.Results. We observed an increase in M-MDSCs and G-MDSC at day 1 following cardiac surgery. The most pronounced increase was found in monocytic-myeloid derived suppressor cells, i.e. an 8-fold increase in M-MDSCs in all study groups at day 1 after surgery. The number of M-MDSCs remained high in patients with persistent MODS at day 7 after cardiac surgery. Levels of IL-6 and IL-10 increased at day 1 after surgery. IL-6 reached its peak level, signifcantly exceeding baseline levels. By day 7, blood levels of all cytokines have decreased, except IL-10 levels, which remained above the baseline in patients with persistent MODS.Conclusion. An increase in M-MDSCs and elevated serum levels of the anti-inflammatory cytokine IL-10 have been found in patients regardless of the presence or absence of the complications in the early postoperative period after cardiac surgery with cardiopulmonary bypass. Persistent MODS with the SOFA scoring > 5 scores at day 7 after cardiac surgery, is associated with an increase in M-MDSCs and elevated levels of the anti-inflammatory cytokine IL-10, related to higher rate of hospital infections, prolonged intensive care unit stay and higher mortality
The role of the quality production process of the business entitles in volatile environment
© 2015, Canadian Center of Science and Education. All rights reserved. The purpose of the article is to develop the conditions to improve innovation activity of the business entities and find the source of the macroeconomic dynamics. The presented article determines coordination between the positions of general and strategic management in the field of total quality management of a business entity to achieve continuous improvement in all areas of business. The foundation of the submitted work serves the idea of total quality management spread over the strategic planning inside a business structure in terms of institutional transformation of the national economy. This article describes the effects of the company’s financial improvement resulting from implementation of the quality tools into the strategic planning system of the industrial business structures. The article is intended for chief managers, executives, researchers dealing with quality management and strategic planning of the business structures
Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production
This paper reviews basic modern trends in obtainment of anti-rabies immunoglobulin with enhanced properties. One of these trends is associated with the substitution of organ-tissue antigen by cultural antigen at the stage of producer immunization. Analyzed are the results of research connected with the use of the cell-cultures grown Rabies virus in production of heterologous anti-rabies immunoglobulin. The study testifies of applicability of the transferred Vero cell culture as a substrate for rabies antigen preparation. In addition to this, specified are the advantages of the rabies cultural antigen usage over the organ-tissue one at the stage of hyper-immune serum production
Callus formation ability in cultivated peanuts (<i>Arachis hypogaea</i> L.)
Background: Russia is one of the largest peanut importing countries. At the same time, in the south of the country, several zones meet the requirements for peanut cultivation. It is possible to increase the yield of the existing peanut varieties by using modern biotechnology methods, in particular agrobacterial transformation. It is known from the literature data that different peanut genotypes and explants from various sources react differently to in vitro regeneration. Successful regeneration depends on the correct protocol, including both the type of regeneration and the composition of media promoting growth and in vitro induction.Objectives: a technique for obtaining peanut regenerants in in vitro culture.Materials and methods: Eight peanut accessions from the VIR collection of different origin were used in the work. Embryonic explants were grown on Murashige-Skoog medium supplemented with the hormone 2,4-dichlorophenoxyacetic acid (2,4-D).Results and conclusions: As a result of assessing the regenerative ability of peanuts grown on Murashige-Skoog medium with the hormone 2,4-D at a concentration of 2 g/L, differences in the callus formation ability were revealed in different accessions. Those with catalog numbers k-793, k-2054 and k-2055 did not form organogenic calli, while accessions k-698 and k-1987 showed the highest percentage of callus formation from embryonic explants
Comparison of American mink embryonic stem and induced pluripotent stem cell transcriptomes
BACKGROUND: Recently fibroblasts of many mammalian species have been reprogrammed to pluripotent state using overexpression of several transcription factors. This technology allows production of induced pluripotent stem (iPS) cells with properties similar to embryonic stem (ES) cells. The completeness of reprogramming process is well studied in such species as mouse and human but there is not enough data on other species. We produced American mink (Neovison vison) ES and iPS cells and compared these cells using transcriptome analysis. RESULTS: We report the generation of 10 mink ES and 22 iPS cell lines. The majority of the analyzed cell lines had normal diploid chromosome number. The only ES cell line with XX chromosome set had both X-chromosomes in active state that is characteristic of pluripotent cells. The pluripotency of ES and iPS cell lines was confirmed by formation of teratomas with cell types representing all three germ layers. Transcriptome analysis of mink embryonic fibroblasts (EF), two ES and two iPS cell lines allowed us to identify 11831 assembled contigs which were annotated. These led to a number of 6891 unique genes. Of these 3201 were differentially expressed between mink EF and ES cells. We analyzed expression levels of these genes in iPS cell lines. This allowed us to show that 80% of genes were correctly reprogrammed in iPS cells, whereas approximately 6% had an intermediate expression pattern, about 7% were not reprogrammed and about 5% had a "novel" expression pattern. We observed expression of pluripotency marker genes such as Oct4, Sox2 and Rex1 in ES and iPS cell lines with notable exception of Nanog. CONCLUSIONS: We had produced and characterized American mink ES and iPS cells. These cells were pluripotent by a number of criteria and iPS cells exhibited effective reprogramming. Interestingly, we had showed lack of Nanog expression and consider it as a species-specific feature
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