462 research outputs found
Flight investigation of approach and flare from simulated breakout altitude of a subsonic jet transport and comparison with analytical models
Satisfactory and optimum flare windows are defined from pilot ratings and comments. Maximum flare normal accelerations, touchdown rates of sink, and total landing maneuver time increments are summarized as a function of approach airspeed margin (with respect to reference airspeed) and flare initiation altitude. The effects of two thrust management techniques are investigated. Comparisons are made with predictions from three analytical models and the results of a simulator study. The approach speed margin was found to have a greater influence on the flare initiation altitude than the absolute airspeed. The optimum airspeed was between the reference airspeed and the reference airspeed plus 10 knots. The optimum flare initiation altitude range for unrestricted landings was from 11 meters to 20 meters (36 feet to 66 feet), and the landing time in the optimum window was 8 seconds. The duration of the landing maneuver increased with increasing flare initiation altitude and with increasing speed margins on the approach
Flight evaluation of the transonic stability and control characteristics of an airplane incorporating a supercritical wing
A TF-8A airplane was equipped with a transport type supercritical wing and fuselage fairings to evaluate predicted performance improvements for cruise at transonic speeds. A comparison of aerodynamic derivatives extracted from flight and wind tunnel data showed that static longitudinal stability, effective dihedral, and aileron effectiveness, were higher than predicted. The static directional stability derivative was slower than predicted. The airplane's handling qualities were acceptable with the stability augmentation system on. The unaugmented airplane exhibited some adverse lateral directional characteristics that involved low Dutch roll damping and low roll control power at high angles of attack and roll control power that was greater than satisfactory for transport aircraft at cruise conditions. Longitudinally, the aircraft exhibited a mild pitchup tendency. Leading edge vortex generators delayed the onset of flow separation, moving the pitchup point to a higher lift coefficient and reducing its severity
Precision controllability of the F-15 airplane
A flying qualities evaluation conducted on a preproduction F-15 airplane permitted an assessment to be made of its precision controllability in the high subsonic and low transonic flight regime over the allowable angle of attack range. Precision controllability, or gunsight tracking, studies were conducted in windup turn maneuvers with the gunsight in the caged pipper mode and depressed 70 mils. This evaluation showed the F-15 airplane to experience severe buffet and mild-to-moderate wing rock at the higher angles of attack. It showed the F-15 airplane radial tracking precision to vary from approximately 6 to 20 mils over the load factor range tested. Tracking in the presence of wing rock essentially doubled the radial tracking error generated at the lower angles of attack. The stability augmentation system affected the tracking precision of the F-15 airplane more than it did that of previous aircraft studied
Intrinsic Fano factor of nuclear recoils for dark matter searches
Nuclear recoils in germanium and silicon are shown to have much larger
variance in electron-hole production than their electron-recoil counterparts
for recoil energies between 10 and 200\,keV. This effect--owing primarily to
deviations in the amount of energy given to the crystal lattice in response to
a nuclear recoil of a given energy--has been predicted by the Lindhard model.
We parameterize the variance in terms of an intrinsic nuclear recoil Fano
factor which is 24.30.2 and 268 at around 25\,keV for silicon and
germanium respectively. The variance has important effects on the expected
signal shapes for experiments utilizing low-energy nuclear recoils such as
direct dark matter searches and coherent neutrino-nucleus scattering
measurements.Comment: 9 pages, 6 figure
Patient access to complex chronic disease records on the internet
Background: Access to medical records on the Internet has been reported to be acceptable and popular with patients, although most published evaluations have been of primary care or office-based practice. We tested the feasibility and acceptability of making unscreened results and data from a complex chronic disease pathway (renal medicine) available to patients over the Internet in a project involving more than half of renal units in the UK.
Methods: Content and presentation of the Renal PatientView (RPV) system was developed with patient groups. It was designed to receive information from multiple local information systems and to require minimal extra work in units. After piloting in 4 centres in 2005 it was made available more widely. Opinions were sought from both patients who enrolled and from those who did not in a paper survey, and from staff in an electronic survey. Anonymous data on enrolments and usage were extracted from the webserver.
Results: By mid 2011 over 17,000 patients from 47 of the 75 renal units in the UK had registered. Users had a wide age range (<10 to >90 yrs) but were younger and had more years of education than non-users. They were enthusiastic about the concept, found it easy to use, and 80% felt it gave them a better understanding of their disease. The most common reason for not enrolling was being unaware of the system. A minority of patients had security concerns, and these were reduced after enrolling.
Staff responses were also strongly positive. They reported that it aided patient concordance and disease management, and increased the quality of consultations with a neutral effect on consultation length. Neither patient nor staff responses suggested that RPV led to an overall increase in patient anxiety or to an increased burden on renal units beyond the time required to enrol each patient.
Conclusions: Patient Internet access to secondary care records concerning a complex chronic disease is feasible and popular, providing an increased sense of empowerment and understanding, with no serious identified negative consequences. Security concerns were present but rarely prevented participation. These are powerful reasons to make this type of access more widely available
The Green Bank Northern Celestial Cap Pulsar Survey II: The Discovery and Timing of Ten Pulsars
We present timing solutions for ten pulsars discovered in 350 MHz searches
with the Green Bank Telescope. Nine of these were discovered in the Green Bank
Northern Celestial Cap survey and one was discovered by students in the Pulsar
Search Collaboratory program in analysis of drift-scan data. Following
discovery and confirmation with the Green Bank Telescope, timing has yielded
phase-connected solutions with high precision measurements of rotational and
astrometric parameters. Eight of the pulsars are slow and isolated, including
PSR J09302301, a pulsar with nulling fraction lower limit of 30\% and
nulling timescale of seconds to minutes. This pulsar also shows evidence of
mode changing. The remaining two pulsars have undergone recycling, accreting
material from binary companions, resulting in higher spin frequencies. PSR
J05572948 is an isolated, 44 \rm{ms} pulsar that has been partially recycled
and is likely a former member of a binary system which was disrupted by a
second supernova. The paucity of such so-called `disrupted binary pulsars'
(DRPs) compared to double neutron star (DNS) binaries can be used to test
current evolutionary scenarios, especially the kicks imparted on the neutron
stars in the second supernova. There is some evidence that DRPs have larger
space velocities, which could explain their small numbers. PSR J1806+2819 is a
15 \rm{ms} pulsar in a 44 day orbit with a low mass white dwarf companion. We
did not detect the companion in archival optical data, indicating that it must
be older than 1200 Myr.Comment: 9 pages, 5 figure
A Case of Cushing’s Syndrome due to Ectopic Adrenocorticotropic Hormone Secretion from Esthesioneuroblastoma with Long Term Follow-Up after Resection
We present a case of a 52-year-old male who developed Cushing’s Syndrome due to ectopic adrenocorticotrophic hormone (ACTH) secretion from a large esthesioneuroblastoma (ENB) of the nasal sinuses. The patient initially presented with polyuria, polydipsia, weakness, and confusion. Computed tomography scan of the head and magnetic resonance imaging showed a 7 cm skull base mass centered in the right cribriform plate without sella involvement. Work-up revealed ACTH-dependent hypercortisolemia, which did not suppress appropriately after high-dose dexamethasone. Subsequent imaging of the chest, abdomen, and pelvis did not reveal other possible ectopic sources of ACTH secretion besides the ENB. His hospital course was complicated by severe hypokalemia and hyperglycemia before successful surgical resection of the tumor, the biopsy of which showed ENB. Postoperatively, his ACTH level dropped below the limit of detection. In the ensuing 4 months, he underwent adjuvant chemoradiation with carboplatin and docetaxel with good response and resolution of hypokalemia and hyperglycemia, with no sign of recurrence as of 30 months postoperatively. His endogenous cortisol production is rising but has not completely recovered
Clinical Manifestations of an Outbreak of Monkeypox Virus in Captive Chimpanzees in Cameroon, 2016
Monkeypox virus (MPXV) is a re-emerging virus of global concern. An outbreak of Clade I MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak. Clinical signs included exanthema, facial swelling, peri-laryngeal swelling, and eschar. Mpox can be lethal in captive chimpanzees with death likely resulting from respiratory complications. We advise avoiding anesthesia in animals with respiratory signs to reduce the likelihood of death. This outbreak presented a risk to animal care staff. There is a need for increased awareness and a One Health approach to preparation for outbreaks in wildlife rescue centers in primate range states where MPXV occurs. Control measures should include quarantining affected animals, limiting human contacts, surveillance of humans and animals, use of personal protective equipment, and regular decontamination of enclosures.</p
The increasing importance of atmospheric demand for ecosystem water and carbon fluxes
Soil moisture supply and atmospheric demand for water independently limit—and profoundly affect—vegetation productivity and water use during periods of hydrologic stress1, 2, 3, 4. Disentangling the impact of these two drivers on ecosystem carbon and water cycling is difficult because they are often correlated, and experimental tools for manipulating atmospheric demand in the field are lacking. Consequently, the role of atmospheric demand is often not adequately factored into experiments or represented in models5, 6, 7. Here we show that atmospheric demand limits surface conductance and evapotranspiration to a greater extent than soil moisture in many biomes, including mesic forests that are of particular importance to the terrestrial carbon sink8, 9. Further, using projections from ten general circulation models, we show that climate change will increase the importance of atmospheric constraints to carbon and water fluxes in all ecosystems. Consequently, atmospheric demand will become increasingly important for vegetation function, accounting for >70% of growing season limitation to surface conductance in mesic temperate forests. Our results suggest that failure to consider the limiting role of atmospheric demand in experimental designs, simulation models and land management strategies will lead to incorrect projections of ecosystem responses to future climate conditions
- …