7 research outputs found
Sonographic Image of Solitary Kidney in Wilms Tumour Survivors
Background/Aims: This study presents an analysis of the sonographic and laboratory parameters of solitary kidney in Wilms tumour survivors (TWs) and compares these parameters with those of healthy individuals. Methods: Fifty-three TWs who completed treatment for Wilms tumour and 44 healthy individuals were enrolled. The study protocol consisted of completing a medical history, sonographic examination of the solitary kidney, estimation of glomerular filtration rate (eGFR) by the Schwartz or MDRD formulas, albumin urine excretion and BP measurement. Results: Sonographic signs of kidney damage were observed in 22 (41,5%) TWs. The most frequently detected abnormalities are hyperechoic rings around renal pyramids (28,3% TWs). Hypertrophy of the solitary kidney occurred in 71,7% of cases. The mean volume of the solitary kidney was 77% of the sum of the two kidney volumes in the control group. The median eGFR in the TWs group was 117 with 25Q-105,5, 75Q-130 ml/min/1,73 m2 vs 131,8 with 25Q-124, 75Q-140 ml/min/1,73 m2 in the control group (p=0,000). Six TWs (11,3%) had a value of eGFR below 90 ml/min/1,73 m2. Increased urine albumin excretion (> 30 mg/g) was observed in 7 TWs (13,2%) and in 3 (6,8%) individuals in the control group. Conclusion: Ultrasonographic abnormalities in solitary kidney of TWs are frequent. The most frequently detected abnormalities are hyperechoic rings around renal pyramids. Sonographic examination of TWs ought to be performed not only to detect tumour recurrence but also to assess the signs of kidney damage and their progression
The Use of Handheld Ultrasound Devices-An EFSUMB Position Paper
Publisher Copyright: © 2018 Georg Thieme Verlag KG Stuttgart New York.The miniaturization of ultrasound equipment in the form of tablet-or smartphone-sized ultrasound equipment is a result of the rapid evolution of technology and handheld ultrasound devices (HHUSD). This position paper of the European Federation of Societies in Ultrasound and Medicine (EFSUMB) assesses the current status of HHUSD in abdominal ultrasound, pediatric ultrasound, targeted echocardiography and heart ultrasound, and we will report position comments on the most common clinical applications. Also included is a SWOT (Strength-Weaknesses-Opportunities-Threats) analysis, the use for handheld devices for medical students, educational & training aspects, documentation, storage and safety considerations.Peer reviewe
The prevalence of incidentaloma - asymptomatic thyroid nodules in the Tricity (Gdansk, Sopot, Gdynia) population
Introduction: The increased sensitivity of imaging devices
raised number of incidentally discovered lesions in various
organs of the human body. Thyroid gland is one of them.
Reported prevalence of ultrasonographically detected thyroid
nodules (incidentalomas) in general population ranges
from 5.2 to 67.0%. Our study demonstrated occurrence of
this clinical problem in the general population of the Tricity.
Material and methods: 135 healthy adults (95 women and
40 men) were examined. Neck palpation, ultrasonographic
examinations of thyroid gland and serum tyreotropin (TSH)
level measurement were made.
Results: In 8.9% of examine (12/135) persons nodules were
palpable whereas in 14.8% (20/135) they were detectable only
in ultrasonographic examination. Altogether thyroid ultrasound
and palpation revealed nodules in 23.7% (32/135)
of all cases. Multiple nodules were present in 12.0% of the
cases. The pathology was more common in the elderly and
in women. TSH serum level was within normal range in all
cases of incidentaloma with otherwise normal thyroid gland. Conclusions: Prevalence of thyroid gland nodules (palpation
- 8.9% plus ultrasonography - 14.8%) in healthy population
of Gdansk, Gdynia and Sopot is close to data reported
in southern Finland (27.0%) and Belgium (19.0%),
where iodine deficiency is small, like in the Tricity area. The
revealed lesions were over two times more frequent in the
female population. Most of the nodules were not palpable.Wstęp: Czułość radiologicznych metod obrazowania ma
wpływ na częstość rozpoznawania przypadkowych, niemych
klinicznie zmian ogniskowych w różnych narządach człowieka,
w tym także w gruczole tarczowym. Częstość incydentalnych
guzków tarczycy wykrytych ultrasonograficznie
waha się, w różnych populacjach, w granicach 5,2–67,0%.
W niniejszej pracy przedstawiono ten problem na przykładzie
populacji mieszkańców Trójmiasta (Gdańsk, Sopot, Gdynia).
Materiał i metody: W badaniu uczestniczyło 135 zdrowych
osób (95 kobiet i 40 mężczyzn). U każdego biorącego udział
w badaniu pacjenta wykonano badanie przedmiotowe szyi,
ultrasonografię (USG) gruczołu tarczowego oraz zmierzono
stężenie hormonu tyreotropowego (TSH, thyroid-stimulating
hormone) w surowicy.
Wyniki: U 8,9% wszystkich uczestników badania (12/135)
palpacyjnie stwierdzono guzki tarczycy. Natomiast wyłącznie
ultrasonograficzne występowanie zmian ogniskowych tarczycy
stwierdzono u dalszych 14,8% badanych osób (20/135).
Zatem łącznie zmiany palpacyjne i wykryte w USG stwierdzono
u 23,7% (32/135) badanych. Mnogie guzki w badaniu
USG wykryto w 12,0% przypadków. Zmiany te były
częstsze u kobiet i osób starszych. Stężenie TSH nie wykazywało
istotnych korelacji z prawdopodobieństwem występowania
guzka incydentalnego.
Wnioski: Częstość występowania guzków tarczycy (w badaniu
palpacyjnym - 8,9% po dodatkowym wykonaniu
badania ultrasonograficznego - 14,8%) w populacji zdrowych
mieszkańców Trójmiasta jest zbliżona do wyników
uzyskanych w południowej Finlandii (27,0%) i Belgii
(19,0%), gdzie niedobór jodu w środowisku jest mały, podobnie
jak na Pomorzu. Incydentalne guzki tarczycy prawie
2-krotnie częściej występowały u kobiet niż u mężczyzn.
Większość zmian ogniskowych tarczycy odkrytych ultrasonograficznie
nie była wyczuwalna w badaniu palpacyjnym
Glomerular filtration rate and prevalence of chronic kidney disease in Wilms’ tumour survivors
Glomerular filtration rate (GFR) was evaluated in 32 Wilms’ tumour survivors (WTs) in a cross-sectional study using 99 Tc-diethylene triamine pentaacetic acid (99 Tc-DTPA) clearance, the Schwartz formula, the new Schwartz equation for chronic kidney disease (CKD), cystatin C serum concentration and the Filler formula. Kidney damage was established by beta-2-microglobulin (B-2-M) and albumin urine excretion, urine sediment and ultrasound examination. Blood pressure was measured. No differences were found between the mean GFR in 99 Tc-DTPA and the new Schwartz equation for CKD (91.8 ± 11.3 vs. 94.3 ± 10.2 ml/min/1.73 m2 [p = 0.55] respectively). No differences were observed between estimated glomerular filtration rate (eGFR) using the Schwartz formula and the Filler formula either (122.3 ± 19.9 vs. 129.8 ± 23.9 ml/min/1.73 m2 [p = 0.28] respectively). Increased urine albumin and B-2-M excretion, which are signs of kidney damage, were found in 7 (22%) and 3 (9.4%) WTs respectively. Ultrasound signs of kidney damage were found in 14 patients (43%). Five patients (15.6%) had more than one sign of kidney damage. Eighteen individuals (56.25%) had CKD stage I (10 with signs of kidney damage; 8 without). Fourteen individuals (43.75%) had CKD stage II (6 with signs of kidney damage; 8 without). The new Schwartz equation for CKD better estimated GFR in comparison to the Schwartz formula and the Filler formula. Furthermore, the WT survivors had signs of kidney damage despite the fact that GFR was not decreased below 90 ml/min/1.73 m2 with 99 Tc- DTPA