54 research outputs found
Functional K ATP channels in the rat retinal microvasculature: topographical distribution, redox regulation, spermine modulation and diabetic alteration
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66207/1/jphysiol.2009.169003.pd
Variation of Rumen Bacterial Diversity in Steers after the Beginning of Grazing
Holstein heifers before or after puberty often are herded on public pastures in Japan. The herbage intake and rumen fermentation of grazing heifers that are not adapted for fresh herbage decreases due to a change of feed from stall-fed dried forage to fresh herbage. This limits their performance during the first several weeks on pasture. Thus, the feeding program such as supplementation before and after the beginning of grazing is important. An increase in ammonia concentration and a decline in fibre degradation in the rumen of a heifer (both of which occur simultaneously with low herbage intake and rumen fermentation) would be caused by the reduced capacity of various bacteria to produce peptides and degrade fibre (Oshio and Tahata 1981). This suggests that variation in rumen bacterial diversity plays an important role in herbage intake and rumen fermentation. However, less information is available on how bacterial diversity in heifers varies during the first few weeks of grazing. This information will provide the basis for designing nutritional management programs for heifers before and after the beginning of grazing. The objective of this study was to determine how herbage intake, digestibility, and rumen bacterial diversity vary in steers that have started grazing without adaptation for fresh herbage during the first 4 weeks after the beginning of grazing
Small airway disease associated with Sjögren’s syndrome: Clinico-pathological correlations
SummaryBackgroundRelationships among clinical, physiological, imaging and pathological findings of small airway disease associated with Sjögren’s syndrome have remained unclear.Subjects and methods: We retrospectively studied 14 patients who underwent surgical lung biopsy and who were diagnosed with small airway disease associated with primary or secondary Sjögren’s syndrome. We compared clinical, bronchoalveolar lavage, physiological, imaging and pathological findings between primary and secondary Sjögren’s syndrome. We scored HRCT and pathological abnormalities and investigated correlations among physiological, HRCT and pathological data, changes in physiological parameters and in HRCT scores after two years of treatment, as well as correlations between these values and pathological scores.ResultsBronchoalveolar lavage fluid, physiological, imaging and pathological findings of the airways did not significantly differ between primary and secondary Sjögren’s syndrome. Air trapping on HRCT negatively correlated with MEF50 and MEF25. Although lymphoid cell infiltration and peribronchiolar fibrosis were the most common pathologies, constrictive change scores correlated negatively with MEF50 and MEF25, positively with air trapping scores and negatively with improvements after therapy in MEF50, MEF25 and air trapping.ConclusionsConstrictive change was the most significant determinant of physiological and imaging presentations and of changes in these factors after therapy for small airway disease associated with Sjögren’s syndrome
Behavior of Latent Vector of Trivariate Wishart Matrix
This paper is concerned with the probability density function of the latent vector corresponding to the largest latent root of Wishart matrix. The latent vector may be expressed by the polar coordinates. Sugiyama (1966) give the exact expression of the probability density function of the polar coordinates. The function contained the alternating series, thus the function may not be converged on the domain of definition, numerically. In this paper we derived an improved expression of the function to be the positive series, for which we provide graphs of a population latent vector and latent roots.【査読有
Completing the Census of Ly-alpha Emitters at the Reionization Epoch
We carried out extended spectroscopic confirmations of Ly-alpha emitters
(LAEs) at z=6.5 and 5.7 in the Subaru Deep Field. Now, the total number of
spectroscopically confirmed LAEs is 45 and 54 at z=6.5 and 5.7, respectively,
and at least 81% (70%) of our photometric candidates at z=6.5 (5.7) have been
spectroscopically identified as real LAEs. We made careful measurements of the
Ly-alpha luminosity, both photometrically and spectroscopically, to accurately
determine the Ly-alpha and rest-UV luminosity functions (LFs). The
substantially improved evaluation of the Ly-alpha LF at z=6.5 shows an apparent
deficit from z=5.7 at least at the bright end, and a possible decline even at
the faint end, though small uncertainties remain. The rest-UV LFs at z=6.5 and
5.7 are in good agreement, at least at the bright end, in clear contrast to the
differences seen in the Ly-alpha LF. These results imply an increase in the
neutral fraction of the intergalactic medium from z=5.7 to 6.5. The rest-frame
equivalent width (EW_0) distribution at z=6.5 seems to be systematically
smaller than z=5.7, and it shows an extended tail toward larger EW_0. The
bright end of the rest-UV LF can be reproduced from the observed Ly-alpha LF
and a reasonable EW_0-UV luminosity relation. Integrating this rest-UV LF
provides the first measurement of the contribution of LAEs to the photon budget
required for reionization. The derived UV LF suggests that the fractional
contribution of LAEs to the photon budget among Lyman break galaxies
significantly increases towards faint magnitudes. Low-luminosity LAEs could
dominate the ionizing photon budget, though this inference depends strongly on
the uncertain faint-end slope of the Ly-alpha LF.Comment: 19 pages, 14 figures. Accepted for publication in Ap
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