10 research outputs found

    A telehealth application for adequate hospital visit advice by physicians affected users’ subsequent hospital visit behavior: a historical cohort study with machine learning

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    IntroductionThe effectiveness of telehealth strategies toward support for adequate hospital visits is vital. We examined whether individuals who received advice from a physician via an online application subsequently visited hospitals. Further, we examined the background factors associated with their hospital visit behavior.MethodsWe used machine learning to examine whether chief complaint, medical advice, and user background characteristics could be used to predict their subsequent hospital visit.ResultsAmong 7,152 participants, those in their 30s were the most frequent users. The proportion of each medical advice was significantly different between the group that did and the one that did not follow physicians’ advice. We further performed supervised machine learning using random forest modeling to categorize those who (1) followed physicians’ advice or (2) did not follow physicians’ advice. The area under the receiver operating characteristic curve was 0.677. Consequently, the aforementioned model soundly categorized whether users followed physicians’ advice. Chief complaint and medical advice were the most important variables to predict whether users followed the advice.DiscussionThe telehealth system to provide support for adequate hospital visits influenced patients’ subsequent hospital visit behavior. Patients’ chief complaint was the most important variable in discriminating whether users followed physicians’ advice

    SARS-CoV-2 suppression and early closure of bars and restaurants: a longitudinal natural experiment

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    Abstract Despite severe economic damage, full-service restaurants and bars have been closed in hopes of suppressing the spread of SARS-CoV-2 worldwide. This paper explores whether the early closure of restaurants and bars in February 2021 reduced symptoms of SARS-CoV-2 in Japan. Using a large-scale nationally representative longitudinal survey, we found that the early closure of restaurants and bars decreased the utilization rate among young persons (OR 0.688; CI95 0.515–0.918) and those who visited these places before the pandemic (OR 0.754; CI95 0.594–0.957). However, symptoms of SARS-CoV-2 did not decrease in these active and high-risk subpopulations. Among the more inactive and low-risk subpopulations, such as elderly persons, no discernible impacts are observed in both the utilization of restaurants and bars and the symptoms of SARS-CoV-2. These results suggest that the early closure of restaurants and bars without any other concurrent measures does not contribute to the suppression of SARS-CoV-2

    Protective effect of estrogen combined with aspirin against re-stenosis of vein graft

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    Catalytic Asymmetric Organozinc Additions to Carbonyl Compounds

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    Chiral Tertiary Diamines in Asymmetric Synthesis

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