Personality Subtypes and Attachment Styles in Women Survivors of Breast and Gynecologic Cancer

Introduction: Gynecologic and breast cancers are among the types of cancer that are still highly prevalent with high rates of mortality due to lack of early diagnosis. However, these two types of cancer can be controlled by screening programs and the individual can be survived. Also, both cancers have gained the attention of mental health specialists because of impairing sexual function and issues related to body image, and fertility status among affected individuals in which, have direct effects on their adjustment and quality of life. Consequently, the aim of the current research is identify of personality subtypes and attachment styles in women who have survived from breast and gynecologic cancers.Methods: The current study is a qualitative. The participants were selected through purposive sampling method, which continued until data saturation from January to March 2018. For the data collection, the Shedler-Western Assessment Procedure (SWAP) and the Adult Attachment Interview (AAI), and for the data analysis Q-Sort scaling and comparative content analysis were used.Results: The study’s findings showed that high-functioning depressive traits and dissociation were high. However, 9 of the participants had psychological health. Also, secure attachment and preoccupied attachment patterns were the most frequent ones.Conclusion: These findings can provide clinical implications for mental variables that are involved in the remission process or the advancement of the disease in women with breast and gynecologic cancer.Declaration of Interest: Non

Specific migration of Bisphenol-A Diglycidyl Ether (BADGE) and its derivatives in four different temperatures in epoxy lacquer

      Migration of compounds from packaging materials is one of the most important aspects of food safety. Epoxy resins have been in inner coatings of food cans since the 1960s. These resins can be produced from Bisphenol-A Diglycidyl Ether (BADGE) that is also utilized as a starter. Migration of potentially toxic compounds in epoxy resins used for commercial cans is a very important food safety issue. Residual BADGE from epoxy coating can be hydrolyzed and chlorohydrolysed into two degradation products, which correspond to its first and second hydrolysis and chlorohydrolyse products. Specific migration of these compounds was evaluated in two water-based food stimulants: %3 acetic acid and %15 ethanol at various temperatures (-6, 5, 25 and 40 ̊C) during 10 days. Solid Phase Extraction (SPE) was used to fortify analysts. A flourimetric-detection RP-HPLC was applied to separation and quantification of BADGE, its hydrolysis and chlorohydroxy derivatives. The EU has adjusted the specific migration limit of these compounds in food due to migration from can coatings. Higher levels of migration were found in 15% ethanol than 3% acetic acid. The results illustrated that decreasing of temperature up to –6 ̊C was increased migration. The highest concentration was observed in BADGE.H2O up to 0.9 mg/Kg. Migration of these compounds takes place in food stimulants; the amounts were lower than exceeding EU limits

Surface Modification of Polyethersulfone-Based Nanofiltration Membrane Using Carboxylated Graphene Oxide and Polyethyleneimine

Hypothesis: Carbxylated graghene oxide nanosheets were synthesized and the nanosheets were applied to the surface modification of the polyethersulfonebased nanofiltration membranes for water treatment.Methods: Different concentrations of the synthesized carboxylated graphene oxide nanosheets were used as the surface modifiers to prepare the PES/PEI c-GO nanofiltration membranes. The prepared membranes were analyzed by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), 3D surface images (AFM) and X-ray diffraction (EDX) spectroscopy. The permeability and the separation performance of the constructed membranes were evalueted by the water contact angle, water content, the flow of pure water and the rejection of sodium sulfate salt and heavy metals.Findings: the FTIR analysis showed the formation of favorable bonds in the synthesized carboxylated graphene oxide nanosheets and the fabricated membranes. The membrane surface modification by c-GO nanosheets led to a decrease in membrane roughness and the contact angle decreased from 75° for the neat membrane to 36° for M1 at 0.001 g of carboxylated graphene oxide nanosheets. Moreover, the water content increased and M2 showed the highest water content. The highest pure water flux was obtained at 13.065 L/m2.h for the constructed M2 membrane containing 0.01 g of carboxylated graphene oxide nanosheets. In addition, the highest rejection of sodium sulfate salt (Na2SO4) was observed 67.5 % for the M3 membrane containing 0.1 g of c-GO nanosheets and the highest rejection of copper nitrate (Cu(NO3)2) was obtained 87.21% for the M1 membrane containing 0.001 g of c-GO nanosheets. Furthermore the obtained results indicated the improvement of the anti-fouling properties of the modified membranes containing carboxylated graphene oxide nanosheets compared to the base membrane

Women places and spaces in contemporary American mosque

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 104).There is an ever-present demand for Mosques in American cities to accommodate the more than 8 percent of the American population that are Muslims; the majority of which are American-born Muslims or American converts. However, Muslim-American communities have implemented the same architectural vocabulary of mosques seen in the Middle East into their American neighborhoods. Nevertheless, this architectural transplantation from the Middle East to America does not come without problems. The weaving of Middle Eastern architectural culture with an American application of Islam, which is prominent within Modern American society, gives rise to internal tensions felt within the community, in particular to the issue of Muslim women's' place in community mosques. Through the numerous case studies and investigations of the American Mosques that I documented, it is clear that the community does not provide adequate spaces for their women members. My thesis explores the process of modifying and developing a new architectural vocabulary for the American mosques within the confinements and boundaries in Islam, in particular, creating an adequate space for women. A lack of attention to the needs of American Muslim women in the states has caused a gender conflict over the adequacy of spaces for Muslim women within American mosques. For example, in the 2006 controversial documentary titled the "Mosque of Morgantown"1 , located in West Virginia, a significant dilemma was created dividing the Muslim community residing in the United States. The "Mosque of Morgantown" set the social precedent for some Muslim women to question some of the religious rulings regarding prayers and set the tone for numerous other protests, of which the most recent occurred at the Islamic Center of Washington DC. In early part of 2010, the Islamic Center of Washington D.C.2 had an outburst of escalating tensions between genders. Thirty Washington D.C. women united in protest and refused to pray in the basement of the mosque, which was their designated area of worship. Instead they decided to attend prayers under the same roof as the men during worship. This seemingly simple act of protest was frowned upon. The Imam of the mosque declared that the allocated rows were for men only. The presence of women in the rows resulted in the delay of the obligatory Friday prayer that is mandatory for men in Islam. Through these incidences, it is clear that an investigation of a new architectural expression, within the confinement of the religion, for women-driven spaces needs to be conducted.by Maryam Eskandari.S.M

Yeast-Lactobacillus Co-Cultures as in situ Ethanol Producers for Flavor Ester Synthesis using Lipase in Fermented Milks

Background and objective: Nowadays, novel biotechnological methods are preferred for flavoring productions since traditional methods include disadvantages. The aim of this study was to assess in situ biosynthesis of natural fruity flavors in fermented milks using microbial co-cultures and lipase enzyme. Materials and methods: Trans esterification of milk fats with ethanol was carried out to develop fruity flavors in ultra-high-temperature whole milks using lipase of Palatase coupled with ethanol fermentation. Kluyveromyces marxianus NCYC 1425 was used to produce in situ ethanol in co-cultures with Lactobacillus fermentum PCC or Lactobacillus paracasei L26. Effects of co-culturing on cell viability and fermentation progress were assessed using enumeration of viable cells and measurement of pH in samples at 0, 24 (Palatase addition) and 48 h (end of fermentation). Headspace solid phase microextraction-gas chromatography (SPME)-MS/FID was used for ester, ethanol and free fatty acid analyses at the beginning and end of the fermentation. Standard curve of ethanol was used to assess the products in terms of being Halal. Results and conclusion: Kluyveromyces marxianus included synergistic effects on Lactobacillus paracasei growth as well as antagonistic effects on Lactobacillus fermentum growth. Antimicrobial effects were seen in Kluyveromyces marxianus-Lactobacillus paracasei co-cultures when Palatase was added. Palatase significantly increased ester levels of the fermented samples. The co-cultures did not include significant differences in shorter chain ester levels (esters of 4-7 carbon chain fatty acids); in contrast, Kluyveromyces marxianus- Lactobacillus fermentum resulted in higher levels of longer chain esters. Although the Kluyveromyces marxianus cultures resulted in higher ester levels compared to that its co-cultures did, the cultures can be used as appropriate adjunct cultures with Lactobacillus cultures to boost flavor ester synthesis. This flavor synthesis can be an appropriate alternative for artificial flavoring agents

Antihyperglycemic activity of quince (Cydonia oblonga Mill.) fruit extract and its fractions in the rat model of diabetes

Introduction: Diabetes mellitus is a metabolic disease that has affected approximately 10% of population worldwide. Cydonia oblonga Mill. (C. oblonga), commonly called quince, contains diverse phytochemical constituents with a broad range of pharmacological activities. The current study is aimed to investigate the antihyperglycemic effect of aqueous extract of Cydonia oblonga Mill. fruit (ACO) in streptozotocin-induced diabetic rats and to identify the active fraction. Methods and Results: Diabetes was induced in rats by a single intraperitoneal (i.p.) injection of 60 mg/kg streptozotocin. The antihyperglycemic activity of different concentrations of ACO (80, 160 and 240 mg/kg body weight daily for a period of 28 days) was evaluated in the diabetic rats by measuring their fasting blood glucose (FBG). Furthermore, the antihyperglycemic effects of two major fractions of ACO were evaluated for the identification of active fraction. Finally, the chemical composition of the active fraction, methanolic fraction (MF), was examined by gas chromatography-mass spectrometry (GC-MS) assay. The oral administration of ACO on diabetic rats resulted in a significant collapse in FBG in a dose-dependent manner. In addition, the MF was the active fraction and exhibited antihyperglycemic activity in diabetic rats during the experiment. The main component of MF was identified as 5-hydroxymethylfurfural or 5-HMF (a well-known natural compound) that may be responsible, at least partly, for the antidiabetic and antihyperglycemic effects of quince. Conclusion: Our results have demonstrated for the first time that quince possesses antihyperglycemic effect in diabetic rats and the MF of the aqueous extract is active fraction

A survey on the fatty acid composition of cow’s milk in different production systems in Khorramabad, Iran with respect to ω-6:ω-3 ratio

       The ratio of ω-6: ω-3 is connected to the higher risk of non-communicable diseases, thus this ratio is becoming more important than quantity of ω-6 and ω-3 in human nutrition. In countries like Iran, cow’s milk is mainly produced in rural area and less in conventional systems. The lactating cows reared in rural and conventional farms are different in terms of nutrition, daily yields, and proportion of concentrate to forage that these might affect milk fatty acid profiles. Therefore, the aim of this study was to determine the ratio of ω-6: ω-3 in cow’s milk produced in conventional and rural dairy farms in west of Iran, Khorramabad. Twenty bulk milk samples (rural and conventional) were collected from the conventional dairy farms and local milk collection centers. Fatty acid profiles were determined and results showed that conventional milk had higher ω-6 (2.1± 0.4) and lower ω-3 (0.16 ± 0.03) in comparison with rural milk. The ratio of ω-6:ω-3 in rural milk was significantly lower (8:1) than that in conventional milk (13:1) (p<0.01). In conclusion, milk produced in rural dairy farms had better ratio of ω-6:ω-3, thus rural milk could be healthier for human nutrition in terms of ω-3 fatty acids

Chemopreventive effect of quince (Cydonia oblonga Mill.) fruit extract on hepatocellular carcinoma induced by diethylnitrosamine in rats

Introduction: Hepatocellular carcinoma (HCC) or primary liver cancer is one of the most prevalent and deadliest cancers, which has been increasing greatly worldwide. Diethylnitrosamine (DEN) is a well-known environmental toxin and potent hepatocarcinogenic dialkylnitrosoamine present in air, water, and in a number of foodstuffs. In the present study, we evaluated preventive effect of aqueous extract of quince (Cydonia oblonga Mill.) fruit (ACO) against DEN-induced hepatocellular carcinoma (HCC) in rats. Methods and Results: The model of hepatocellular carcinoma was induced by a single intraperitoneal injection of DEN (200 mg/kg) as an initiator that after two weeks followed by daily oral administration of 2-acetylaminofluorene (30 mg/kg) as a promoter for two weeks. Quince-treated rats were pretreated with ACO intragastrically at three different doses two weeks prior to DEN injection. The marked reduction of serum biomarkers of liver damage and cancer, including alfa-fetoprotein (AFP), gamma glutamyl transpeptidase (GGT), alanine transaminase (ALT), and aspartate transaminase (AST) were observed in ACO supplemented animals as compared with HCC rats at the end of the experiment. Moreover, the quince extract exhibited in vivo antioxidant activity by elevating glutathione (GSH) contents as well as preventing lipid peroxidation in the liver tissues of DEN-treated rats. The relative weight of liver was also reduced in quince-treaded rats as a prognostic marker in HCC. Conclusions: Our results clearly demonstrated that quince has a chemopreventive effect against HCC in rats and can be proposed as a promising candidate for the prevention of DEN-induced hepatocarcinogenesis. &nbsp

Prevention of liver cancer by standardized extract of Melissa officinalis L. in a rat model of hepatocellular carcinoma: Its potential role as a chemopreventive agent

Introduction: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver and the third most common cause of cancer-related death worldwide. Melissa officinalis L. (M. officinalis L.), known as lemon balm is a medicinal plant, which has a wide range of pharmacological properties. This study was aimed to assess the chemopreventive effect of aqueous extract of M. officinalis (AMO) against diethyl nitrosamine (DEN)-induced hepatocellular carcinoma (HCC) in rats. Methods and Results: The model of hepatocellular carcinoma was induced by a single intraperitoneal injection of DEN (200 mg/kg) as an initiator and after two weeks was followed by daily oral administration of 2-acetylaminofluorene (30 mg/kg) as a promoter for two weeks. Lemon balm-treated rats were pretreated with AMO intragastrically at three different doses two weeks prior to DEN injection. At the end of the experiment, the marked reduction of serum biomarkers of liver damage and cancer, including alfa-fetoprotein (AFP), gamma glutamyl transpeptidase (GGT), alanine transaminase (ALT), and aspartate transaminase (AST) were observed in AMO complemented rats compared to DEN-treated animals. Furthermore, the extract exhibited in vivo antioxidant activity by elevating GSH concentration and preventing lipid peroxidation in the liver tissues of HCC rats. The relative weight of liver was also reduced in lemon balm-treated rats as a prognostic marker in HCC. Conclusion: Our findings demonstrated that M. officinalis has a chemopreventive effect against HCC in rats and can be suggested as a potential agent for the prevention of primary liver cancer. &nbsp

Cancer chemoprevention by oleaster (Elaeagnus angustifoli L.) fruit extract in a model of hepatocellular carcinoma induced by diethylnitrosamine in rats

Hepatocellular carcinoma (HCC) is a frequent and fatal human cancer with poor diagnosis that accounts for over half a million deaths each year worldwide. Elaeagnus angustifolia L. known as oleaster has a wide range of pharmacological activities. This study aimed to investigate the chemopreventive effect of aqueous extract of E. angustifolia fruit (AEA) against diethylnitrosamine (DEN)-induced HCC in rats. HCC was induced in rats by a single injection of DEN (200 mg/kg) as an initiator. After two weeks, rats were orally administered 2-acetylaminofluorene or 2-AAF (30 mg/kg) as a promoter for two weeks. Oleaster-treated rats were orally pretreated with the increasing doses of AEA two weeks prior to DEN injection that continued until the end of the experiment. In the current study, a significant decrease in serum biomarkers of liver damage and cancer, including alfa-fetoprotein (AFP), gamma glutamyl transpeptidase (GGT), alanine transaminase (ALT), and aspartate transaminase (AST) was observed in AEA-treated rats when compared to HCC rats. Furthermore, the oleaster extract exhibited in vivo antioxidant activity by elevating reduced glutathione (GSH) contents as well as preventing lipid peroxidation in the liver tissues of DEN-treated rats. The relative weight of liver, a prognostic marker of HCC, was also reduced in oleaster-treated rats. To conclude, our results clearly demonstrated that oleaster fruit possesses a significant chemopreventive effect against primary liver cancer induced by DEN in rats. It can be suggested that the preventive activity of oleaster against hepatocarcinogenesis may be mediated through the antioxidant, anti-inflammation, and antimutagenic effects of the fruit