Experimental assembly of structures in EVA: Hardware morphology and development issues

A large body of data was obtained by MIT during neutral boyancy testing at Marshall Space Flight Center from 1980 to the present. These efforts, and the most significant results are summarized. The Experimental Assembly of Structure in EVA (EASE) flight experiment was undertaken to validate these results and flown on the STS 61-B in November 1985. The EASE experiment hardware is discussed and how the experiment goals dictate its size, shape, and operational characteristics, are illustrated

A Phenomenological Study of Mania and Depression

In this thesis I develop a cohesive phenomenological account of mania and depression. Whilst phenomenological insights have been applied to a number of psychiatric disorders – most notably schizophrenia – mania, depression, and bipolar disorder have been neglected. In developing my account I challenge the common understanding of mania and depression as opposed. Through an examination of bodily and temporal experiences in mania and depression I unearth deeper structural commonalities. This allows for greater insight into the relationship between the two states and casts light on ‘mixed episodes’, where features of mania and depression co-occur. In my exploration of bodily experience I argue for an understanding of the depressed body as ‘corporealized’. I show how this helps us to understand common descriptions of the body and the world found in first person accounts. I challenge the intuitive distinction between the body as $\textit{active and invisible}$ and $\textit{inactive and conspicuous}$ by showing that the manic body is both conspicuous and active. I argue that we can enhance our understanding of this bodily experience through an appreciation of the associated temporal experience. Turning to the topic of time, I reveal the inadequacies of accounts that suggest that alterations in experiences of time in mania and depression are restricted to changes in temporal velocity. Using the Husserlian concepts of ‘retention’ and ‘protention’ I develop a new model of temporal experience in mania and depression, arguing that in addition to changes in temporal $\textit{velocity}$ we also find changes in temporal structure. This account allows us to understand common experiences in mania, including feelings of grandiosity, a loss of reflection, and the active yet conspicuous body. Likewise, it casts light on experiences common in depression, including guilt, a perception of recovery as impossible, and feelings of separation from others

Structural Assembly Demonstration Experiment (SADE)

The purpose of the Structural Assembly Demonstration Experiment (SADE) was to create a near-term Shuttle flight experiment focusing on the deployment and erection of structural truss elements. The activities of the MIT Space Systems Laboratory consist of three major areas: preparing and conducting neutral buoyancy simulation test series; producing a formal SADE Experiment plan; and studying the structural dynamics issues of the truss structure. Each of these areas is summarized

Faith Integration in the Higher Education Online Classroom: Perspectives and Practice

Online instruction in higher education has grown dramatically in recent years, and more faith-based colleges and universities are including online courses as a part of their educational offerings. The integration of faith in learning is an important goal in many of these faith-based institutions; however, the practice of faith integration in online settings presents unique challenges for faculty members. The purpose of this article is to provide support for faculty members teaching online in Christian colleges and universities with faith integration by presenting a series of strategies for their use. Approaches to faith integration are grouped utilizing a model presented by Dulaney et al. (2015) and adapted here for online contexts. Recommendations for working with students of differing faith backgrounds are also provided

Girls' education in the late sixteenth and early seventeenth centuries in England and Wales : a study of attitudes and practice

This thesis provides a study of attitudes and practice in respect of female education in England and Wales in the late sixteenth and early seventeenth centuries. It begins with a review of primary and secondary sources, and throughout draws substantially upon personal documents consulted in collections of family papers covering a wide geographical area. These documents, it is argued are broadly representative of gentry families. Chapter Two examines the education of daughters; Chapter Three the role of women in marriage; Chapter Four motherhood. Each of these chapters examines the links between education and the roles girls and women fulfilled. Throughout these three chapters, contrasts and comparisons are drawn between prescriptive advice and practice. Chapter Five considers the difficult issue of standards in the education of girls and women, while the final chapter examines some of the outcomes of education in terms of women as intermediaries in informal power networks, estate and farm managers and educational benefactors and founders. The thesis draws conclusions in respect of the importance of education in permitting the developing role of women in both private and public spheres and examines the reasons for such changes. It also challenges existing theories regarding the differences between Catholic and Protestant attitudes to girls' education. A substantial appendix listing some 870 educated and literate women of the period is provided, both to demonstrate the major sources for this study and to provide a basis for future research

Structural assembly demonstration experiment, phase 1

The goal of this phase of the structural assembly and demonstration experiment (SADE) program was to begin to define a shuttle flight experiment that would yield data to compare on-orbit assembly operations of large space structures with neutral buoyancy simulations. In addition, the experiment would be an early demonstration of structural hardware and human capabilities in extravehicular activity (EVA). The objectives of the MIT study, as listed in the statement of work, were: to provide support in establishing a baseline neutral buoyancy testing data base, to develop a correlation technique between neutral buoyancy test results and on-orbit operations, and to prepare the SADE experiment plan (MSFC-PLAN-913)

Registration of hard white winter wheat germplasms KS14U6380R5, KS16U6380R10, and KS16U6380R11 with adult plant resistance to stem rust

Resistance to the Ug99 group of races of the stem rust fungus Puccinia graminis f. sp. tritici is limited in winter wheat (Triticum aestivum L.) germplasm adapted to the Great Plains of the United States. Our objective was to generate regionally adapted hard winter wheat germplasm with combinations of adult plant resistance genes that are expected to provide durable resistance. KS14U6380R5 (Reg. no. GP-1043, PI 689115), KS16U6380R10 (Reg. no. GP-1044, PI 689116), and KS16U6380R11 (Reg. no. GP-1045, PI 689117) were derived from backcrosses of the hard white winter wheat germplasm KS05HW14 to the stem rust-resistant Kenyan spring wheat cultivar ‘Kingbird’. KS14U6380R5, KS16U6380R11, and KS16U6380R10 were developed by pedigree selection and were initially evaluated as U6380-11-2R-0A, U6380-210-2R-0A, and U6380-148-4R-2T, respectively. The germplasms were developed by the USDA-ARS and jointly released with the Kansas State University Agricultural Experiment Station. These germplasms provide parents for development of hard winter wheat cultivars with durable resistance to stem rust

Space Environmental Effects on the Optical Properties of Selected Transparent Polymers

Transparent polymer films are currently considered for use as solar concentrating lenses for spacecraft power and propulsion systems. These polymer films concentrate solar energy onto energy conversion devices such as solar cells and thermal energy systems. Conversion efficiency is directly related to the polymer transmission. Space environmental effects will decrease the transmission and thus reduce the conversion efficiency. This investigation focuses on the effects of ultraviolet and charged particle radiation on the transmission of selected transparent polymers. Multiple candidate polymer samples were exposed to near ultraviolet (NUV) radiation to screen the materials and select optimum materials for further study. All materials experienced transmission degradation of varying degree. A method was developed to normalize the transmission loss and thus rank the materials according to their tolerance of NUV. Teflon(Tm) FEP and Teflon(Tm) PFA were selected for further study. These materials were subjected to a combined charged particle dose equivalent to 5 years in a typical geosynchronous Earth orbit (GEO). Results from these NUV screening tests and the 5 year GEO equivalent dose are presented

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.

Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine SNPs associated with the extent of abdominal aortic calcification (n = 9,417) or descending thoracic aortic calcification (n = 8,422). Two genetic loci, HDAC9 and RAP1GAP, were associated with abdominal aortic calcification at a genome-wide level (P < 5.0 × 10-8). No SNPs were associated with thoracic aortic calcification at the genome-wide threshold. Increased expression of HDAC9 in human aortic smooth muscle cells promoted calcification and reduced contractility, while inhibition of HDAC9 in human aortic smooth muscle cells inhibited calcification and enhanced cell contractility. In matrix Gla protein-deficient mice, a model of human vascular calcification, mice lacking HDAC9 had a 40% reduction in aortic calcification and improved survival. This translational genomic study identifies the first genetic risk locus associated with calcification of the abdominal aorta and describes a previously unknown role for HDAC9 in the development of vascular calcification