Negotiating urban change. Strategies and tactics of patrimonialization in Hackney Wick, East London

The heritage category function of building collective identity, condensing in specific goods, tangible or intangible, a set of locally significant values and practices, has been often pointed out to show its use in managing relations between the authorities and local communities (Simonicca 2015). This happens nowadays with a particularly conscious approach in urban planning, not only in the practices and rhetorics of institutions, but also in the quotidian experience of people who develop their own informal planning. In this discussion, the heritage arguments become an appropriate tool to handle and shape the change, especially when these processes have a deep impact in the everyday lives of communities and territories, like in cases of gentrification

Static and dynamic properties of synaptic transmission at the cyto-neural junction of frog labyrinth posterior canal

The properties of synaptic transmission have been studied at the cyto-neural junction of the frog labyrinth posterior canal by examining excitatory postsynaptic potential (EPSP) activity recorded intraaxonally from the afferent nerve after abolishing spike firing by tetrodotoxin. The waveform, amplitude, and rate of occurrence of the EPSPs have been evaluated by means of a procedure of fluctuation analysis devised to continuously monitor these parameters, at rest as well as during stimulation of the semicircular canal by sinusoidal rotation at 0.1 Hz, with peak accelerations ranging from 8 to 87 deg.s-2. Responses to excitatory and inhibitory accelerations were quantified in terms of maximum and minimum EPSP rates, respectively, as well as total numbers of EPSPs occurring during the excitatory and inhibitory half cycles. Excitatory responses were systematically larger than inhibitory ones (asymmetry). Excitatory responses were linearly related either to peak acceleration or to its logarithm, and the same occurred for inhibitory responses. In all units examined, the asymmetry of the response yielded nonlinear two-sided input-output intensity functions. Silencing of EPSPs during inhibition (rectification) was never observed. Comparison of activity during the first cycle of rotation with the average response over several cycles indicated that variable degrees of adaptation (up to 48%) characterize the excitatory response, whereas no consistent adaptation was observed in the inhibitory response. All fibers appeared to give responses nearly in phase with angular velocity, at 0.1 Hz, although the peak rates generally anticipated by a few degrees the peak angular velocity. From the data presented it appears that asymmetry, adaptation, and at least part of the phase lead in afferent nerve response are of presynaptic origin, whereas rectification and possible further phase lead arise at the encoder. To confirm these conclusions a simultaneous though limited study of spike firing and EPSP activity has been attempted in a few fibers

Introduction : political subjectivity in times of crisis

Modernity is often understood as a time of crisis. Health, humanitarian, economic, and environmental crises are just some crises characterizing the present. This special issue investigates these interwoven crises by investigating the subject in crisis, as making sense of how our worlds are changing requires interrogating how we ourselves are changing. How can we apprehend the subject and forms of subjectivities implied when evoking specific crises responses? In this introduction, we suggest reading current crises as expressions, effects, and accelerations of a longstanding epistemological crisis sustaining the modern articulation of subjectivity. To trace the subjectivity/crisis link we mobilize Derrida's notion of aporia, which exposes the unresolvable tension(s) at the foundation of concepts, to survey how subjectivity has been examined in political theory and international relations (IR) and to posit the continued necessity of immanent critiques of modern subjectivity. We conclude by setting out the individual contributions to this special issue.Publisher PDFPeer reviewe

Parents, schools and human capital differences across countries

Results from international standardized tests show large cross-country differences in students’ performances. Where do these gaps come from? This paper argues that differences in cultural environments and parental inputs may be of great importance. We show that the school performance of second generation immigrants is closely related with the one of native students in their parents’ countries of origin. This holds true even after accounting for different family background characteristics, schools attended and selection into immigration. We quantify the overall contribution of various parental inputs to the observed cross-country differences in the PISA test performance, and show that they account for about 40% of the gap between East Asia and other regions. This pattern questions whether PISA scores should be interpreted only as a quality measure for a country’s educational system. They actually contain an important intergenerational and cultural component

Chemotherapy-induced alopecia management: Clinical experience and practical advice

Background: Chemotherapy-induced alopecia (CIA) is probably one of the most shocking aspects for oncological patients and underestimated by physicians. Among hair loss risk factors, there are treatment-related aspects such as drug dose, admin- istration regimen, and exposure to X-rays, but also patient-related characteristics. To the best of our knowledge, no guidelines are available about CIA management. Aims and methods: With this study, based on literature background and our clinical experience, we would like to propose a list of actions in order to estimate the risk of hair loss before starting chemotherapy and to manage this condition before, dur- ing, and after drug administration and to create a sort of practical guide for derma- tologists and oncologists. Results and conclusion: There is an urgent need for prospective studies to clarify the mechanistic basis of alopecia associated with these drugs and consequently to design evidence-based management strategies

Multi-therapies in androgenetic alopecia: review and clinical experiences.

Androgenetic alopecia (AGA) is a genetically determined progressive hair-loss condition which represents the most common cause of hair loss in men. The use of the medical term androgenetic alopecia reflects current knowledge about the important role of androgens and genetic factors in its etiology. In addition to androgen-dependent changes in the hair cycle, sustained microscopic follicular inflammation contributes to its onset. Furthermore, Prostaglandins have been demonstrated to have the ability in modulating hair follicle cycle; in particular, PGD2 inhibits hair growth while PGE2/F2a promote growth. Due to the progressive nature of AGA, the treatment should be started early and continued indefinitely, since the benefit will not be maintained upon ceasing therapy. To date, only two therapeutic agents have been approved by the Food and Drug Administration and European Medicines Agency for the treatment of AGA: topical minoxidil and oral finasteride. Considering the many pathogenetic mechanisms involved in AGA, various treatment options are available: topical and systemic drugs may be used and the choice depends on various factors including grading of AGA, patients’ pathological conditions, practicability, costs and risks. So, the treatment for AGA should be based on personalized therapy and targeted at the different pathophysiological aspects of AG

A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options

Rosacea is a common chronic inflammatory disorder showing a wide range of clinical features such as telangiectasia, erythema, papules, and pustules primarily involving the central part of face (forehead, cheeks and nose) although extra facial manifestation have been described. We describe a case of rosacea with predominant scalp involvement successfully treated with a 8-week-course of doxycycline 40 mg once a day and probiotic therapy twice a day (Bifidobacterium breve BR03, Lactobacillus salivarius LS01 1 × 10(9) UFC/dose)

PELATIHAN CARA PENGOLAHAN PANGAN YANG BAIK (CPPB) PADA KELOMPOK UKM OLAHAN PANGAN DI DESA CILEUNYI KULON, JAWA BARAT

Desa Cileunyi Kulon memiliki beberapa usaha kecil menengah (UKM) yang bergerak di bidang pengolahan pangan, diantaranya memproduksi keripik singkong, keripik pisang, baso goreng (basreng), roti, kerupuk, dan lain-lain. Namun demikian proses pengolahannya masih banyak yang belum menerapkan cara pengolahan pangan yang baik (CPPB). Oleh sebab itu, kegiatan ini bertujuan untuk memberikan pelatihan pada kelompok UKM tersebut untuk memperbaiki proses produksi yang diharapkan dapat memperbaiki kualitas produk dan daya saing UKM. Kegiatan dilakukan melalui skema pengabdian kepada masyarakat (PKM) yang terintegrasi dengan kuliah kerja nyata (KKN) mahasiswa Universitas Padjadjaran. Kegiatan dimulai dengan survey pada para pelaku UKM, pemaparan materi pelatihan dan diskusi interaktif, dan pendampingan pada para pelaku UKM. Kegiatan ini telah meningkatkan pengetahuan para pelaku UKM terkait dengan Cara pengolahan pangan yang baik, kerusakan dan bahaya penggunaan minyak goreng bekas, sanitasi dan keamanan pangan, serta manajemen dan pemasaran. Kegiatan ini juga bermanfaat bagi mahasiswa KKN dalam pembelajaran bermasyarakat, dan meotivasi pelaku UKM pengolahan pangan di Desa Cileunyi Kulon untuk terus bangkit, tumbuh, dan berkembang

Quantitative and differential analysis of ciliate protozoa in rumen content samples filtered before and after fixation

The objective of this study was to assess whether the straining of rumen content samples influences the estimation of protozoal density. Ninety rumen samples were obtained from 30 cattle (three samples per animal). The samples were subjected to one of three treatments at the moment of collection: 1) fixation informalin without straining(control treatment), 2) straining before fixation informalin, or 3)straining after fixation informalin.To test the hypothesis of the variation in the protozoa composition in the samples, multivariate analyses with non-metric multidimensional scaling (NMDS) were carried out. The diversity and density of rumen protozoa were negatively affected by straining before fixation.In the pre-filtered sample, the number of ciliates from the genus Entodinium was reduced, and no individuals from the Diploplastron, Elytroplastron and Eudiplodinium genera were detected; these effects were not observed in the other two treatments. Straining after fixation did not interfere with the diversity of the ruminal community, but the abundance of protozoa was greater thanin the control treatment and significantly greater than in the samples filtered before fixation. These factors suggest that post-fixation straining is the recommended technique to analyze rumen protozoa.