Ecolog?a tr?fica de coptodon rendalli en un embalse de los Andes colombianos

58 p. Recurso Electr?nicoCoptodon rendalli es un C?chlido africano que en los a?os 60 ingres? al territorio colombiano colonizando diferentes sistemas de la cuenca del r?o Magdalena y en los embalses se ha convertido en un importante recurso pesquero. Fue introducida en el embalse de Porce II (r?o Porce? Antioquia-Colombia) en el a?o 2000 y aunque sustenta la pesca en este sistema? se conoce poco sobre esta especie. Su dieta se compone de detrito? algas? macr?fitas? macroinvertebrados y peces en menor frecuencia. Dada su importancia como recurso pesquero? se realiz? un estudio de dieta basado en el an?lisis de contenidos estomacales de individuos capturados entre junio y diciembre de 2012. Se analizaron 189 muestras colectadas por Fundaci?n Humedales y EPM encontrando 48 ?tems? siendo las diatomeas el recurso m?s utilizado. La composici?n de la dieta estuvo levemente asociada con el nivel del agua del embalse. La amplitud de recursos usados en la dieta fue baja, concentr?ndose principalmente en microorganismos del plancton. No se encontraron diferencias en la dieta asociadas con la clase de talla (LS). Las condiciones del embalse en t?rminos de oferta de recursos planct?nicos han sido favorables para el crecimiento de la poblaci?n de esta especie. Esta investigaci?n fue realizada dentro del convenio No. 2011000558 entre la Universidad de Antioquia con Empresas P?blicas de Medell?n.Coptodon rendalli is an African C?chlid, in the 60s entered the Colombian territory colonizing different systems of the Magdalena River and reservoirs has become an important fishery resource. It was introduced in the Porce II reservoir (Porce river, Antioquia-Colombia) in 2000 and although fishing based on this system, little is known about this species. Their diet consists of detritus, algae, macrophytes, macroinvertebrates and fish less often. Given its importance as a fishing resort, a diet study based on the analysis of stomach contents of individuals caught between June and December 2012. We analyzed 189 samples collected by Fundacion Humedales and EPM founded 48 items, with more resource diatoms used. The composition of the diet was slightly associated with the water level of the reservoir. The breadth of resources used in the diet was low, focusing mainly on plankton organisms. No differences in diet associated with class size (LS). Reservoir conditions in terms of supply of planktonic resources have been favorable for the growth of the population of this species. This research was conducted under the agreement No. 2011000558 by the Universidad de Antioquia with Empresas P?blicas de Medell?n Key words: Trophic ecology, invasive species, Andean reservoi

Deciphering Adipose Tissue Extracellular Vesicles Protein Cargo and Its Role in Obesity

The extracellular vesicles (EVs) have emerged as key players in metabolic disorders rising as an alternative way of paracrine/endocrine communication. In particular, in relation to adipose tissue (AT) secreted EVs, the current knowledge about its composition and function is still very limited. Nevertheless, those vesicles have been lately suggested as key players in AT communication at local level, and also with other metabolic peripheral and central organs participating in physiological homoeostasis, and also contributing to the metabolic deregulation related to obesity, diabetes, and associated comorbidities. The aim of this review is to summarize the most relevant data around the EVs secreted by adipose tissue, and especially in the context of obesity, focusing in its protein cargo. The description of the most frequent proteins identified in EVs shed by AT and its components, including their changes under pathological status, will give the reader a whole picture about the membrane/antigens, and intracellular proteins known so far, in an attempt to elucidate functional roles, and also suggesting biomarkers and new paths of therapeutic action

Proyecto de automatizaci?n de una planta concentradora de 7,500 TMPD

El proyecto consiste en desarrollar el sistema de automatizaci?n para una planta concentradora de 7500 TMPD en modalidad EPC (Ingenier?a, Procura y Construcci?n), se desarrolla para el sector minero, espec?ficamente para al grupo internacional privado Minera Centuria, el proyecto est? ubicado en la ciudad de Cerro de Pasco. El proyecto contempla automatizar las ?reas de chancado, molienda, flotaci?n y reactivos, las fases de ejecuci?n del proyecto son: Ingenier?a, procura, programaci?n, implementaci?n y puesta en marcha. El proyecto no debe exceder los 3.6 millones de d?lares y el tiempo m?ximo de ejecuci?n no debe ser mayor a 18 meses, iniciando en enero de 2021 y finalizando en junio de 2022. La l?nea base de costos del proyecto asciende a 3.35 millones de d?lares, donde los gastos directos representan el 93.5% de dicho monto, sobre los riesgos analizados se considera una reserva de contingencia que asciende a 72,020 d?lares. Se considera que el montaje el?ctrico y mec?nicos de los equipos en campo, ser?n realizados por una contrata externa, para ello durante la etapa de procura se desarrollan los criterios de selecci?n para la empresa que realizar? los trabajos, as? como el modelo del contrato a implementar

ZNF577 Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet

The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epigenetic mark of breast cancer associated with obesity. The aim of the current study was to investigate differences in methylation levels of ZNF577 depending on obesity, menopausal state and dietary pattern in blood leukocytes, a non-invasive sample. The methylation levels of ZNF577 of two CpG sites (CpGs) located in promoter and island previously identified as differentially methylated according to adiposity and menopausal state by 450 k array (cg10635122, cg03562414) were evaluated by pyrosequencing in DNA from the blood leukocytes of breast cancer patients [n = 90; n = 64 (71.1%) overweight/obesity and n = 26 (28.9%) normal-weight] and paired tumor tissue biopsies (n = 8 breast cancer patients with obesity; n = 3/5 premenopausal/postmenopausal women). Differences in methylation levels were evaluated at each CpGs individually and at the mean of the two evaluated CpGs. Adherence to the Mediterranean diet was evaluated using the MEDAS-validated questionnaire, and the consumption of food groups of interest was also evaluated using the recommended intakes of the Sociedad Espanola de Nutricion Comunitaria. The methylation levels of ZNF577 were correlated between paired leukocytes and breast tumor biopsies (r = 0.62; p = 0.001). Moreover, higher methylation was found in leukocytes from patients with obesity (p = 0.002) and postmenopausal patients (p = 0.022) than patients with normal-weight or premenopausal, respectively. After adjusting for the body mass index and age, higher levels of ZNF577 methylation were also found in women with greater adherence to the Mediterranean diet (p = 0.017) or specific foods. Relevantly, the methylation levels of ZNF577 showed a good ability for fish consumption detection [area under the ROC curve (AUC) = 0.72; p = 0.016]. In conclusion, the association between methylation of ZNF577 and adiposity, menopausal state, and adherence to the Mediterranean diet can be detected in the blood leukocytes. The results guarantee the need of performing further studies in longer longitudinal cohorts in order to elucidate the role of ZNF577 methylation in the association between breast cancer, adiposity and dietary patterns

Desarrollo de la oferta de caf?s de especialidad (Honey) con alta valoraci?n en taza para tostadores de Estados Unidos : plan de negocios para la empresa Peruvian Harvest Agronegocios SAC en joint venture con la CACFEVAM Ltda. en el valle de Alto Mayo (Regi?n San Mart?n)

El presente estudio tiene por objetivo proponer un modelo de negocio para la empresa Peruvian Harvest en Joint Venture con la Cooperativa Agraria Cafetalera Fe y Esperanza Valle del Alto Mayo Ltda., incrementando la calidad mediante la producci?n de caf?s especiales con proceso Honey, que permita a la empresa diversificar la oferta del productor frente al tostador, para ser m?s competitivos y tener la capacidad de negociar con mejores precios. Este plan de negocios est? enfocado en innovaci?n de proceso mediante la producci?n de caf?s especiales con procesos honey, contribuyendo al cuidado del medio ambiente, puesto que en este proceso el grano de caf? se separa del cerezo sin el uso de agua, sin procesos de fermentaci?n y lavado, y se convierte en un caf? ecol?gico; mediante este tipo de proceso el caf? sufre cambios en su composici?n, que permiten incrementar la calidad de taza del producto final que saldr? al mercado. El an?lisis econ?mico nos confirma que el plan de negocio es viable y rentable lo que permitir? el crecimiento de la empresa y la cooperativa, teniendo un VNA financiero positivo de S/1, 170,955 y una TIR de 45.27% y con una Tasa de descuento (CPPC) del 13.88%

Propuesta de un plan de negocio, basado en tecnolog?a, para atenci?n de consultas e incidentes relacionados a dispositivos electr?nicos

El servicio de soporte t?cnico se ha venido prestando de manera tradicional a lo largo del tiempo. Sin embargo, no se ha evidenciado la existencia de alg?n proveedor, que brinde este servicio de manera integral, siendo independiente del dispositivo, marca y plataforma. En ese sentido, la presente tesis, propone un modelo de negocio que, fundament?ndose en tecnolog?a como elemento diferenciador, busca atender las consultas e incidentes de los usuarios de manera integral, eliminando la complejidad de buscar al proveedor que compete un determinado incidente. Asimismo, el uso de tecnolog?a, permitir? brindar un primer nivel de servicio totalmente gratuito, y otro pagado, que ser? el que generar?a ingresos a la empresa. En ambos casos, se buscar? maximizar la eficiencia en cuanto a operaciones y calidad del servicio. Finalmente, se ha contemplado tambi?n el uso de tecnolog?a anal?tica, que permita mejorar las operaciones de la empresa a lo largo del tiempo. Por ejemplo, mediante la consulta a bases de datos de conocimiento, lo cual permitir? una mayor eficiencia en la soluci?n de incidentes

Wage inequality, segregation by skill and the price of capital in an assignment model

Some pieces of empirical evidence suggest that in the U.S., over the last few decades, (i) wage inequality between-plants has risen much more than wage inequality within-plants and (ii) there has been an increase in the segregation of workers by skill into separate plants. This paper presents a frictionless assignment model in which these two features can be explained simultaneously as the result of the decline in the relative price of capital. Additional implications of the model regarding the skill premium and the dispersion in labor productivity across plants are also consistent with the empirical evidence. [resumen de autor

The labor market effects of technology shocks

We analyze the effects of neutral and investment-specific technology shocks on hours worked and unemployment. We characterize the response of unemployment in terms of job separation and job finding rates. We find that job separation rates mainly account for the impact response of unemployment while job finding rates for movements along its adjustment path. Neutral shocks increase unemployment and explain a substantial portion of unemployment and output volatilityinvestment-specific shocks expand employment and hours worked and mostly contribute to hours worked volatility. We show that this evidence is consistent with the view that neutral technological progress prompts Schumpeterian creative destruction, while investment specific technological progress has standard neoclassical feature