Una panoramica generale dell'approccio svedese all’educazione inclusiva

This article is set to inform about the Swedish school system, parts of the Swedish teacher education, didactical considerations using co-teaching for inclusion and some ongoing Swedishresearch about simulation training within teacher education for special needs teachers and ways to improve pupils reading skills. The work has been done as literature studies of earlier researchand regulatory documents as well as case studies of teacher education at Linköping University where they use simulation training and ongoing research in a municipality in Sweden where theyuse response to intervention (RTI) to support pupils to become faster and more confident at coming up with answers to addition and subtraction problems. The case study about simulation training showed how simulations could be used to train the ability for teacher for special needs training and teachers for special educational needs ability to observe, a skill that is of great importance in taking stock of a situation and carrying out an investigation in school practices. The influence of the instructor/teacher when using different ways of teaching such as simulation was also showed. The case study about RTI showed that fewer pupils than expected have automatic recall of number combinations, which has the consequence that a larger group than expected will carry on practice with help of adapted computer program

Pathfinders or Explorers : Student teachers’ ways of handling the challenges of classroom management in a simulation

Acknowledgements This research has been supported by the Swedish Research Council [reference number 721-2011-4741]Peer reviewedPublisher PD

Tracing patterns of sloyd teachers' efficacy beliefs at different stages of their professional careers

Peer reviewe

Förändring på tapeten

The purpose of this study is to describe and analyze conditions SMEs face to use the business model to communicate and implement strategic change. We wish to compare these factors to the current literature on business models and explain differences between SME and bigger companies conditions. The purpose has been examined through a qualitative study. A case study has been conducted on one company meeting our criteria. To strengthen our finding a benchmark has been made through an interview with a consultant with great experience and knowledge on the area. Theories on strategy, strategic change and business models, along with studies in these areas specifically regarding SMEs, have been examined to create a theoretical framework for our study. Primary data was gathered through six semi-structured interview with the employees of Audio Pro. An interview with a consultant with broad practical experience was also conducted. Based on our study we have observed that SMEs often work with strategy as a part of their daily routines, which leads to a more implicit strategy. This makes the strategy hard to describe and therefore impede strategic change. Through the use of a simple and graphical business model SME can improve the communication of strategic change both internally and externally.Syftet med denna uppsats är att beskriva och analysera SMF:s förutsättningar för att använda affärsmodellen som hjälpmedel för att kommunicera och driva strategisk förändring. Vi vill kontrastera dessa mot den befintliga forskningen om affärsmodeller och se om det finns skillnader mellan SMF och stora företag i förutsättningarna för användandet av affärsmodell som hjälpmedel. Uppsatsen är en kvalitativ undersökning gjord genom en fallstudie där ett företag har djupanalyserats. För att testa de funna fenomenen har en benchmarking skett genom en intervju med person med stor kunskap och erfarenhet av SMF och strategi.Litteratur och teorier kring strategi, strategisk förändring och affärsmodeller har undersökts för att konstruera en teoretiskt referensram för vår studie. Det empiriska materialet består av sex semi-strukturerade intervjuer med medarbetare hos Audio Pro samt en intervju med en sakkunnig individ inom området på ett praktiskt plan. Utifrån vår studie har vi sett att SMF arbetar med strategi som en del av sitt löpande arbete och att det ofta bildar en underförstådd strategi. Detta leder till en svårighet att uttrycka strategin vilket försvårar strategisk förändring. Genom att använda en enkel grafisk affärsmodell kan SMF lättare kommunicera sin strategi både internt och extern vilket kan förenkla implementeringen av förändrad strategi

Strategy for improved NH2 detection in combustion environments using an Alexandrite laser

A new scheme for NH2 detection by means of laser-induced fluorescence (LIF) with excitation around wavelength 385 nm, accessible using the second harmonic of a solid-state Alexandrite laser, is presented. Detection of NH2 was confirmed by identification of corresponding lines in fluorescence excitation spectra measured in premixed NH3-air flames and on NH2 radicals generated through NH3 photolysis in a nonreactive flow at ambient conditions. Moreover, spectral simulations allow for tentative NH2 line identification. Dispersed fluorescence emission spectra measured in flames and photolysis experiments showed lines attributed to vibrational bands of the NH2 A2A1 ← X2B1 transition but also a continuous structure, which in flame was observed to be dependent on nitrogen added to the fuel, apparently also generated by NH2. A general conclusion was that fluorescence interferences need to be carefully considered for NH2 diagnostics in this spectral region. Excitation for laser irradiances up to 0.2 GW/cm2 did not result in NH2 fluorescence saturation and allowed for efficient utilization of the available laser power without indication of laser-induced photochemistry. Compared with a previously employed excitation/detection scheme for NH2 at around 630 nm, excitation at 385.7 nm showed a factor of ~ 15 higher NH2 signal. The improved signal allowed for single-shot NH2 LIF imaging on centimeter scale in flame with signal-to-noise ratio of 3 for concentrations around 1000 ppm, suggesting a detection limit around 700 ppm. Thus, the presented approach for NH2 detection provides enhanced possibilities for characterization of fuel-nitrogen combustion chemistry

Improved Pairwise Measurement-Based Surface Code

We devise a new realization of the surface code on a rectangular lattice of qubits utilizing single-qubit and nearest-neighbor two-qubit Pauli measurements and three auxiliary qubits per plaquette. This realization gains substantial advantages over prior pairwise measurement-based realizations of the surface code. It has a short operation period of 4 steps and our performance analysis for a standard circuit noise model yields a high fault-tolerance threshold of approximately $0.66\%$. The syndrome extraction circuits avoid bidirectional hook errors, so we can achieve full code distance by choosing appropriate boundary conditions. We also construct variants of the syndrome extraction circuits that entirely prevent hook errors, at the cost of larger circuit depth. This achieves full distance regardless of boundary conditions, with only a modest decrease in the threshold. Furthermore, we propose an efficient strategy for dealing with dead components (qubits and measurements) in our surface code realization, which can be adopted more generally for other surface code realizations. This new surface code realization is highly optimized for Majorana-based hardware, accounting for constraints imposed by layouts and the implementation of measurements, making it competitive with the recently proposed Floquet codes.Comment: 38 pages, 32 figure

A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer

Primate-specific NBL2 macrosatellite is hypomethylated in several types of tumors, yet the consequences of this DNA hypomethylation remain unknown. We show that NBL2 conserved repeats are close to the centromeres of most acrocentric chromosomes. NBL2 associates with the perinucleolar region and undergoes severe demethylation in a subset of colorectal cancer (CRC). Upon DNA hypomethylation and histone acetylation, NBL2 repeats are transcribed in tumor cell lines and primary CRCs. NBL2 monomers exhibit promoter activity, and are contained within novel, non-polyA antisense lncRNAs, which we designated TNBL (Tumor-associated NBL2 transcript). TNBL is stable throughout the mitotic cycle, and in interphase nuclei preferentially forms a perinucleolar aggregate in the proximity of a subset of NBL2 loci. TNBL aggregates interact with the SAM68 perinucleolar body in a mirror-image cancer specific perinucleolar structure. TNBL binds with high affinity to several proteins involved in nuclear functions and RNA metabolism, such as CELF1 and NPM1. Our data unveil novel DNA and RNA structural features of a non-coding macrosatellite frequently altered in cancer

Microalbuminuria and retinopathy in adolescents and young adults with type 1 and type 2 diabetes.

AIM: To estimate the occurrence of complications related to early-onset type 2 diabetes compared with type 1 diabetes. METHODS: All individuals registered in the Swedish Pediatric Quality Diabetes Register and the Swedish National Diabetes Register with type 2 diabetes diagnosis at 10 to 25?years of age between 1996 and 2014 (n = 1413) were included. As controls, individuals with type 1 diabetes were randomly selected from the same registers and were matched for age, sex, and year-of-onset (n = 3748). RESULTS: Of the adolescents with type 2 diabetes in the pediatric register, 7.7% had microalbuminuria and 24.6% had signs of retinopathy 5?years after diagnosis, whereas the adolescents with type 1 diabetes 3.8% had microalbuminuria and 19.2% had retinopathy. Among the young adults with type 2 diabetes from the adult diabetes register 10?years after diagnosis 15.2% had microalbuminuria and 39.7% retinopathy, whereas the young adults with type 1 diabetes 4.8% had microalbuminuria and 43.8% retinopathy. After adjustment for established risk factors measured over time in the whole combined cohort, individuals with type 2 diabetes had significantly higher risk of microalbuminuria with a hazard ratio (HR) of 3.32 (95% confidence interval, CI 2.86-3.85, P?< .001), and retinopathy with a HR of 1.17 (95% CI 1.06-1.30, P 0.04). CONCLUSIONS: The prevalence of complications and comorbidities was higher among those with type 2 diabetes compared with type 1 diabetes, although prevalent in both groups. Early monitoring and more active treatment of type 2 diabetes in young individuals is required