An analysis of Leadership and proactivity to face the challenges of industry 5.0

Industry 5.0 is a new technological revolution accompanied by a process of changes as it aims to enhance the transformation of the industrial sector into intelligent spaces based on the Internet of Things, artificial intelligence, and robotics, among others. For this reason, industry 5.0 involves challenges, one of them is the knowledge of people in the fields of robotics and artificial intelligence to achieve adequate interaction between machines and operators. Therefore, the organization’s responsibility is based on training employees in virtual education, in addition to safe training that can prevent employees from going through unnecessary problems during training sessions, in addition to enhancing communication and motivation of employees to obtain interactive knowledge environments [1] and thus can better adapt to these changes; which is why the need arises to find an appropriate leadership style that develops self-initiated behaviors in employees to carry out processes, autonomy to make decisions and confidence to face challenges. This article is important because it analyzes a perspective that has not been analyzed before and is an appropriate leadership style that develops proactive behavior of employees to overcome the challenges of Industry 5.0

Carcinoma renal de células claras. A propósito de un caso y revisión de la literatura

Renal cell cancer (RCC) is the most common solid lesion in the kidney and accounts for approximately 90% of malignant renal tumors. There is a 1.5:1 male predominance and the highest incidence occurs between 60 and 70 years of age. RCC represents 2%-3% of all cancers and its highest incidence occurs in western countries. We report a rare case of a female patient of 35 years of age who has had pain free hematuria for two days. A contrasted abdominal/pelvic CT revealed a lesion of approximately 15 x 12 x 10 cm with neoproliferative appearance and heterogeneous features of hypo and hyperdensity of 40 uH, with neovascularization and contrast enhancement, compromising the middle and lower calyx of the left kidney extensive to renal pelvis. A left radical nephrectomy was performed. Histopathological study revealed a well-differentiated low grade clear cell carcinoma, with free margins and lymph nodes without metastasis. The patient has a satisfactory evolution and is awaiting adjuvant treatment. Due to the fact that the patient is a young adult, the urologist should be able to make the diagnosis as soon as possible.El carcinoma de células renales (CCR) es la lesión sólida más frecuente en el riñón y representa aproximadamente el 90% de los tumores renales malignos. Hay un predominio 1,5:1 de varones sobre las mujeres y su incidencia máxima tiene lugar entre los 60 y 70 años de edad. Este tipo de cáncer representa el 2%-3% de todos los cánceres y su incidencia máxima ocurre en los países occidentales. Se reporta un caso poco frecuente de CCR en una paciente femenina de 35 años de edad con una hematuria total, sin dolor, de 2 días de duración. El TAC abdomino-pélvico reveló una lesión ocupante de espacio de 15 x 12 x 10 cm aproximadamente, de aspecto neoproliferativo, con características heterogéneas de hipo e hiperdensidad, de 40 uH, neovascularización y realce al contraste, que compromete cáliz medio e inferior de riñón izquierdo, extensivo hasta pelvis renal. Se practicó nefrectomía radical izquierda. El estudio histopatológico reporta un carcinoma de células claras bien diferenciado de bajo grado, con márgenes libres y ganglios linfáticos sin MT. Paciente quien evoluciona satisfactoriamente en planificación de terapia adyuvante. Por el hecho de ser una presentación en un adulto joven, lo ideal es que el urólogo este en la capacidad de realizar el diagnóstico a la brevedad posible

El club conversacional: una estrategia interaccional de aprendizaje para estudiantes de inglés como lengua extranjera

The main purpose of this study was to determine the importance of an English conversational club as a leaming interactional strategy for students of English as a Foreign Language. The participants were students of Education from the course English 11 at the Universidad Simón Rodriguez in Caracas. This descriptive investigation helped reviewing the conception of conversational clubs as communicative spaces that allow students to be in contact with the target language in a genuine way. The results revealed that there are not communicative spaces for these apprentices, and that all the surveyed students consider a conversational club as a necessary leaming intera.:tional strategy.El presente estudío tuvo como propósito principal determinar la importancia del uso del club conversacional de inglés como estrategia interaccional de aprendizaje para un grupo de estudiantes de Inglés 11 del programa de educación en La Universidad "Simón Rodriguez" en Caracas. A través de los lineamientos del diseño descriptivo, se revisó la concepción de los clubes de conversación como espacios comunicativos que le permiten al estudiante estar en contacto con el idioma meta de manera genuina. Los resultados obtenidos revelaron 'que no existen espacios comunicativos para dichos aprendices, y que los encuestados en su totalidad consideran necesaria la implementación de un club de conversación como estrategia interaccional de aprendizaje

Familias jurídicas y disciplinas en el estudio del derecho

Fil: Walter, Gustavo R. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Basanta, Alicia. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Barrionuevo, Daniel. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Leiva, Patricia. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Marcial, Adriana. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Chalhub Frau, Silvana. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Assandri, Mónica. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Rinaldi, Sandra. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Robledo, Federico. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.El presente cuadernillo desarrolla ejercicios que presentan a las familias jurídicas en tanto categorías generales en el campo del derecho; sobresaliendo por sobre la gran variedad de ordenamientos jurídicos particulares. Las familias jurídicas son presentadas aquí en función de tradiciones filosóficas, culturales, políticas, geográficas e históricas distintas.Fil: Walter, Gustavo R. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Basanta, Alicia. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Barrionuevo, Daniel. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Leiva, Patricia. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Marcial, Adriana. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Chalhub Frau, Silvana. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Assandri, Mónica. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Rinaldi, Sandra. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Fil: Robledo, Federico. Universidad Nacional de Córdoba. Facultad de Derecho; Argentina.Otras Derech

Mice Deficient in T-bet Form Inducible NO Synthase-Positive Granulomas That Fail to Constrain Salmonella.

Clearance of intracellular infections caused by Salmonella Typhimurium (STm) requires IFN-γ and the Th1-associated transcription factor T-bet. Nevertheless, whereas IFN-γ-/- mice succumb rapidly to STm infections, T-bet-/- mice do not. In this study, we assess the anatomy of immune responses and the relationship with bacterial localization in the spleens and livers of STm-infected IFN-γ-/- and T-bet-/- mice. In IFN-γ-/- mice, there is deficient granuloma formation and inducible NO synthase (iNOS) induction, increased dissemination of bacteria throughout the organs, and rapid death. The provision of a source of IFN-γ reverses this, coincident with subsequent granuloma formation and substantially extends survival when compared with mice deficient in all sources of IFN-γ. T-bet-/- mice induce significant levels of IFN-γ- after challenge. Moreover, T-bet-/- mice have augmented IL-17 and neutrophil numbers, and neutralizing IL-17 reduces the neutrophilia but does not affect numbers of bacteria detected. Surprisingly, T-bet-/- mice exhibit surprisingly wild-type-like immune cell organization postinfection, including extensive iNOS+ granuloma formation. In wild-type mice, most bacteria are within iNOS+ granulomas, but in T-bet-/- mice, most bacteria are outside these sites. Therefore, Th1 cells act to restrict bacteria within IFN-γ-dependent iNOS+ granulomas and prevent dissemination

Diapause as escape strategy to exposure to toxicants: response of Brachionus calyciforus to arsenic

Invertebrate organisms commonly respond to environmental fluctuation by entering diapause. Production of diapause in monogonont rotifers involves a previous switch from asexual to partial sexual reproduction. Although zooplankton have been used in ecotoxicological assays, often their true vulnerability to toxicants is underestimated by not incorporating the sexual phase. We experimentally analyzed traits involved in sexual reproduction and diapause in the cyclically parthenogenetic freshwater rotifer, Brachionus calyciflorus, exposed to arsenic, a metalloid naturally found in high concentrations in desert zones, focusing on the effectiveness of diapause as an escape response in the face of an adverse condition. Addition of sublethal concentrations of arsenic modified the pattern of diapause observed in the rotifer: investment in diapause with arsenic addition peaked earlier and higher than in non-toxicant conditions, which suggests that sexual investment could be enhanced in highly stressed environmental conditions by increased responsiveness to stimulation. Nevertheless, eggs produced in large amount with arsenic, were mostly low quality, and healthy-looking eggs had lower hatching success, therefore it is unclear whether this pattern is optimum in an environment with arsenic, or if rather arsenic presence in water bodies disturbs the optimal allocation of offspring entering diapause. We observed high accumulation of arsenic in organisms exposed to constant concentration after several generations, which suggests that arsenic may be accumulated transgenerationally. The sexual phase in rotifers may be more sensitive to environmental conditions than the asexual one, therefore diapause attributes should be considered in ecotoxicological assessment because of its ecological and evolutionary implications on lakes biodiversity

Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

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